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P wave dispersion, Tpeak–Tend interval, and Tp-e/QT ratio in children with psoriasis

Published online by Cambridge University Press:  08 January 2020

Mecnun Çetin Open the ORCID record for Mecnun Çetin [Opens in a new window] ,
İbrahim H. Yavuz ,
Mehmet Gümüştaş  and
Göknur Ö. Yavuz
Mecnun Çetin*
Affiliation:
Department of Pediatric Cardiology, Van Yuzuncu Yil Universitiy, Van, Turkey
İbrahim H. Yavuz
Affiliation:
Department of Dermatology, Van Yuzuncu Yil Universitiy, Van, Turkey
Mehmet Gümüştaş
Affiliation:
Department of Pediatric Cardiology, Ağrı State Hospital, Ağrı, Turkey
Göknur Ö. Yavuz
Affiliation:
Department of Dermatology, Van Yuzuncu Yil Universitiy, Van, Turkey
*
Author for correspondence: M. Çetin, Department of Pediatric Cardiology, Van Yuzuncu Yil University, Van, Turkey. Tel: +90 4322177600; Fax: +90 4322121954; E-mail: drmecnun@hotmail.com
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Abstract

Background:

Psoriasis is a chronic inflammatory, multi-system disease that often begins in childhood and characterised by inflammatory skin, nails, scalp, and joint manifestations. The inflammation in psoriasis may promote some effect on the cardiac conduction system.

Objective:

The aim of this study is to investigate myocardial repolarisation anomaly on the conducting system in the paediatric psoriasis using P wave dispersion, Tpeak–Tend interval, and Tp-e/QT ratio.

Methods:

Forty-two patients diagnosed with psoriasis and 37 age- and sex-matched healthy children were enrolled in the study. Electrocardiographic parameters in psoriasis and control group were recorded from an electrocardiogram for each patient.

Results:

The results indicated that the parameters including Pdis, QTc dis, Tp-e dis interval, and Tp-e max/QTmax ratios, which are known to be key indicators for the prediction of severe atrial or ventricular arrhythmia and sudden cardiac death and also important parameters used as the indicators for the non-invasive evaluation of the transmural heterogeneity were significantly longer in the study group compared to the control group (p < 0.05).

Conclusions:

This study includes the evidence linking psoriasis with increased myocardial repolarisation heterogeneity. These findings suggest that this patient population may be at an increased risk for arrhythmias. Our findings may be a basis for further studies.

Keywords

ChildrenpsoriasisTp-e disTp-e/QT ratio
Type
Original Article
Information
Cardiology in the Young , Volume 30 , Issue 3 , March 2020 , pp. 318 - 322
Copyright
© Cambridge University Press 2020

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