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Tetralogy of Fallot in men: quality of life, family, education, and employment

Published online by Cambridge University Press:  14 December 2011

Elisabeth Bygstad ,
Lia C. V. M. Pedersen ,
Thais A. L. Pedersen  and
Vibeke E. Hjortdal
Elisabeth Bygstad
Affiliation:
Department of Cardiothoracic and Vascular Surgery, Aarhus University Hospital, Aarhus, Denmark
Lia C. V. M. Pedersen
Affiliation:
Department of Paediatrics, Aarhus University Hospital, Aalborg, Denmark
Thais A. L. Pedersen*
Affiliation:
Department of Cardiothoracic and Vascular Surgery, Aarhus University Hospital, Aarhus, Denmark
Vibeke E. Hjortdal
Affiliation:
Department of Cardiothoracic and Vascular Surgery, Aarhus University Hospital, Aarhus, Denmark
*
Correspondence to: Thais A. L. Pedersen, Department of Cardiothoracic and Vascular Surgery, Aarhus University Hospital, 8200 Aarhus, Denmark. Tel: +45 8949 5481; Fax: +45 8949 6016; E-mail: thais.a.pedersen@ki.au.dk
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Abstract

Introduction

Little is known about the quality of life, health, family, education, and employment status among adult men with repaired tetralogy of Fallot.

Material and methods

A total of 68 men who underwent repair of tetralogy of Fallot between 1971 and 1991 were studied. Fifty-three patients answered the SF-36 health survey and additional questions regarding offspring, education, and employment status. The men with repaired tetralogy of Fallot were compared with 32 healthy men and 40 women who also underwent repair of tetralogy of Fallot in the same period.

Results

The patients scored lower than healthy men in the SF-36 categories physical functioning, general health, and physical component summary. There were no statistically significant differences in the scores from male and female patients except a lower score in bodily pain among women. Educational level for men operated for tetralogy of Fallot was similar to the general male population, whereas fewer were employed and more were retired, undergoing rehabilitation or receiving social benefits. The reproduction rate was lower compared with the general population (0.65 versus 1.02 children per man) but relatively higher than the rate among women with tetralogy of Fallot (0.88 versus 1.84 children per woman). The risk of having a child with congenital heart disease was 8.3%.

Conclusion

Men operated for tetralogy of Fallot have good quality of life and educational status. They start a family, although their reproduction rate is two-thirds that of the general population. The risk of having a child with congenital heart disease is higher compared with the background population. The overall quality of life is similar for men and women operated for tetralogy of Fallot.

Keywords

Congenital heart diseasegrown-up congenital heartreproduction
Type
Original Article
Information
Cardiology in the Young , Volume 22 , Issue 4 , August 2012 , pp. 417 - 423
Copyright
Copyright © Cambridge University Press 2012

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References

1. Apitz, C, Webb, GD, Redington, AN. Tetralogy of Fallot. Lancet 2009; 374: 1462–1471.Google Scholar
2. Pradat, P, Francannet, C, Harris, JA, Robert, E. The epidemiology of cardiovascular defects, part I: a study based on data from three large registries of congenital malformations. Pediatr Cardiol 2003; 24: 195–221.CrossRefGoogle Scholar
3. Hickey, EJ, Veldtman, G, Bradley, TJ, et al. Late risk of outcomes for adults with repaired tetralogy of Fallot from an inception cohort spanning four decades. Eur J Cardiothorac Surg 2009; 35: 156–164.CrossRefGoogle ScholarPubMed
4. Larsen, SH, McCrindle, BW, Jacobsen, EB, Johnsen, SP, Emmertsen, K, Hjortdal, VE. Functional health status in children following surgery for congenital heart disease: a population-based cohort study. Cardiol Young 2010: 1–10.Google Scholar
5. Pedersen, LM, Pedersen, TA, Ravn, HB, Hjortdal, VE. Outcomes of pregnancy in women with tetralogy of Fallot. Cardiol Young 2008; 18: 423–429.CrossRefGoogle ScholarPubMed
6. Garratt, A, Schmidt, L, Mackintosh, A, Fitzpatrick, R. Quality of life measurement: bibliographic study of patient assessed health outcome measures. BMJ 2002; 324: 1417.CrossRefGoogle ScholarPubMed
7. Ware, JE Jr, Sherbourne, CD. The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Med Care 1992; 30: 473–483.CrossRefGoogle ScholarPubMed
8. Danmarks Statistik. Befolkningens udvikling 2008. Vital statistics 2008, 2009.Google Scholar
9. Burn, J, Brennan, P, Little, J, et al. Recurrence risks in offspring of adults with major heart defects: results from first cohort of British collaborative study. Lancet 1998; 351: 311–316.CrossRefGoogle ScholarPubMed
10. Hargrove, A, Penny, DJ, Sawyer, SM. Sexual and reproductive health in young people with congenital heart disease: a systematic review of the literature. Pediatr Cardiol 2005; 26: 805–811.Google Scholar
11. Vigl, M, Hager, A, Bauer, U, et al. Sexuality and subjective wellbeing in male patients with congenital heart disease. Heart 2009; 95: 1179–1183.Google Scholar
12. Wray, J, Sensky, T. Congenital heart disease and cardiac surgery in childhood: effects on cognitive function and academic ability. Heart 2001; 85: 687–691.Google Scholar
13. Murphy, JG, Gersh, BJ, Mair, DD, et al. Long-term outcome in patients undergoing surgical repair of tetralogy of Fallot. N Engl J Med 1993; 329: 593–599.CrossRefGoogle ScholarPubMed
14. Gatzoulis, MA, Balaji, S, Webber, SA, et al. Risk factors for arrhythmia and sudden cardiac death late after repair of tetralogy of Fallot: a multicentre study. Lancet 2000; 356: 975–981.CrossRefGoogle ScholarPubMed
15. Bailliard, F, Anderson, RH. Tetralogy of Fallot. Orphanet J Rare Dis 2009; 4: 2.CrossRefGoogle ScholarPubMed
16. Moons, P, Van, DK, De, GS, Gewillig, M, Budts, W. Is the severity of congenital heart disease associated with the quality of life and perceived health of adult patients? Heart 2005; 91: 1193–1198.Google Scholar
17. van Rijen, EH, Utens, EM, Roos-Hesselink, JW, et al. Current subjective state of health, and longitudinal psychological well-being over a period of 10 years, in a cohort of adults with congenital cardiac disease. Cardiol Young 2005; 15: 168–175.Google Scholar
18. Ternestedt, BM, Wall, K, Oddsson, H, Riesenfeld, T, Groth, I, Schollin, J. Quality of life 20 and 30 years after surgery in patients operated on for tetralogy of Fallot and for atrial septal defect. Pediatr Cardiol 2001; 22: 128–132.CrossRefGoogle ScholarPubMed
19. Moons, P, Van, DK, De, BL, et al. Quality of life and health status in adults with congenital heart disease: a direct comparison with healthy counterparts. Eur J Cardiovasc Prev Rehabil 2006; 13: 407–413.Google Scholar
20. Gratz, A, Hess, J, Hager, A. Self-estimated physical functioning poorly predicts actual exercise capacity in adolescents and adults with congenital heart disease. Eur Heart J 2009; 30: 497–504.Google Scholar