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Ventricular tachycardia secondary to prolongation of the QT interval in a fetus with autoimmune mediated congenital complete heart block

Published online by Cambridge University Press:  03 May 2005

Christopher Duke ,
Graham Stuart  and
John M. Simpson
Christopher Duke
Affiliation:
Department of Paediatric Cardiology, Glenfield Hospital, Leicester, United Kingdom
Graham Stuart
Affiliation:
Congenital Heart Unit, Bristol Royal Hospital for Children, Bristol, United Kingdom
John M. Simpson
Affiliation:
Fetal Cardiology Unit, Department of Congenital Heart Disease, Guy's Hospital, London, United Kingdom
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Abstract

We report a case where fetal echocardiography identified both complete heart block and ventricular tachycardia. The mother tested positive for anti-Ro antibodies. Prenatal detection of this unusual combination of arrhythmias prompted early postnatal evaluation, which revealed prolongation of the QT interval. Autoimmune mediated congenitally complete heart block associated with such prolongation of the QT interval has a poor prognosis. The child was successfully treated with beta blockers and implantation of a pacemaker.

Keywords

Long QT syndromefetal heartanti-Ro antibodyechocardiographyprenatal diagnosisarrhythmia
Type
Brief Report
Information
Cardiology in the Young , Volume 15 , Issue 3 , June 2005 , pp. 319 - 321
Copyright
© 2005 Cambridge University Press

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References

Schleich JM, Bernard Du Haut Cilly F, Laurent MC, Almange C. Early prenatal management of a fetal ventricular tachycardia treated in utero by amiodarone with long-term follow-up. Prenat Diagn 2000; 20: 449–452.Google Scholar
Wu MH, Hsieh FJ, Wang JK, Kau ML. A variant of long QT syndrome manifested as fetal tachycardia and associated with ventricular septal defect. Heart 1999; 82: 386–388.Google Scholar
Rosenbaum MB, Acunzo RS. Pseudo 2:1 atrioventricular block and T wave alternans in the long QT syndromes. J Am Coll Cardiol 1991; 18: 1363–1366.Google Scholar
Esscher E, Michaelsson M. Q-T interval in congenital complete heart block. Pediatr Cardiol 1983; 4: 121–124.Google Scholar
Sholler GF, Walsh EP. Congenital complete heart block on patients without anatomic cardiac defects. Am Heart J 1989; 118: 1193–1198.Google Scholar
Solti F, Szatmary L, Vecsey T, Renyi-Vamos F Jr, Bodor E. Congenital complete heart block associated with QT prolongation. Eur Heart J 1992; 13: 1080–1083.Google Scholar
Kocak G, Atalay S, Tutar E, Imamoglu A, Uysalel A, Guldal M. Congenital complete atrioventricular block in an infant with long QT syndrome. Acta Cardiologica 1998; 53: 153–155.Google Scholar
Groves AMM, Allan LD, Rosenthal E. Outcome of isolated congenital complete heart block diagnosed in utero. Heart 1996; 75: 190–194.Google Scholar
Cimaz R, Stramba-Badiale M, Brucato A, Catelli L, Panzeri P, Meroni PL. QT Interval prolongation in asymptomatic anti-SSA/Ro-positive infants without congenital heart block. Arthritis Rheum 2000; 43: 1049–1053.Google Scholar
Gordon AP, Khamashta MA, Hughes GRV, Rosenthal E. Increase in the heart-rate-corrected QT interval in children of anti-Ro-positive mothers, with a further increase in those with siblings with congenital heart block: comment on the article by Cimaz et al. Arthritis Rheum 2001; 44: 242–243.Google Scholar