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Clinical and therapeutic role of mentalization in schizophrenia—a review

Published online by Cambridge University Press:  21 February 2017

Trisevgeni Dimopoulou ,
Frank I. Tarazi  and
Evangelia M. Tsapakis
Trisevgeni Dimopoulou
Affiliation:
’Aghios Charalambos’ Mental Health Center, Heraklion, Crete, Greece
Frank I. Tarazi
Affiliation:
Department of Psychiatry and Neuroscience Program, Harvard Medical School and McLean Hospital, Boston, Massachusetts, USA
Evangelia M. Tsapakis*
Affiliation:
’Aghios Charalambos’ Mental Health Center, Heraklion, Crete, Greece Department of Psychiatry and Neuroscience Program, Harvard Medical School and McLean Hospital, Boston, Massachusetts, USA
*
*Address for correspondence: Dr. Evangelia M. Tsapakis, ‘Aghios Charalambos’ Mental Health Center, 82, M. Alexandrou Street, 71305 Heraklion, Crete, Greece. (Email: emtsapakis@doctors.org.uk)
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Abstract

Recent empirical findings from clinical and genetic studies suggest that mentalization, a key area of social cognition, is a distinct construct, although it is closely related to the neurocognitive deficits and symptoms of schizophrenia. Mentalization contributes a great deal to impaired social functioning. Current measures often display methodological problems, and many aspects should be taken into account when assessing mentalization. Moreover, advances in cognitive and affective neurosciences have led to the development of more advanced behavioral methods to assess the relationship between cognitive functions, symptoms, and social cognition based on their underlying neural mechanisms. The development of assessment tools that better examine the neural circuitry of such relationships may lead to the development of new psychosocial and pharmacological treatments.

Keywords

First episode patientsmentalizationneurocognitive deficitspharmacotherapyschizophreniasocial functioningtheory of mind
Type
Review Articles
Information
CNS Spectrums , Volume 22 , Issue 6 , December 2017 , pp. 450 - 462
Copyright
© Cambridge University Press 2017 

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