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Fibromyalgia Syndrome: Presentation, Diagnosis, Differential Diagnosis, and Vulnerability

Published online by Cambridge University Press:  07 November 2014

I. Jon Russell  and
Karen G. Raphael
I. Jon Russell*
Affiliation:
Dr. Russell is associate professor of medicine and director of the University Clinical Research Center at the, University of Texas Health Science Center in San Antonio
Karen G. Raphael
Affiliation:
Dr. Raphael is associate professor in the Departments of Psychiatry and Diagnostic Sciences at the, University of Medicine and Dentistry of New Jersey in Newark
*
Department of Medicine, Mail Code 7868, University of Texas Health Center, 7703 Floyd Curl Dr, San Antonio, TX 78229-3900; Tel: 201-567-4661; E-mail: russell@uthscsa.dcci.com
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Abstract

Fibromyalgia syndrome (FMS) presents with widespread soft tissue pain. Common comorbidities include severe insomnia, body stiffness, affective symptoms, irritable bowels, and urethral syndrome. A 1990 research classification depends on a history of widespread pain and prominent tenderness to palpation at 11 or more of 18 specific tender points. It is a criteria-based diagnosis rather than one by exclusion and can accompany other medical conditions. FMS occurs worldwide, and can present any age, but is most common in adult females. Although numerous studies and reviews contend that FMS may be caused by psychological stress such as sexual abuse, a critical epidemiological review fails to support that concept. Existing data suggest that some individuals with FMS may have a dysregulated physiological stress response system that predates the onset of symptoms.

Type
Research Article
Information
CNS Spectrums , Volume 13 , Issue S5 , March 2008 , pp. 6 - 11
Copyright
Copyright © Cambridge University Press 2008

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References

1.Russell, IJ, Bieber, C. Myofascial pain and fibromyalgia syndrome. In: McMahon, SB, Koltzenburg, M, eds. Wall and Melzack’s Textbook of Pain. London, England: Elsevier; 2005: Chapter 44.Google Scholar
2.Wolfe, F, Smythe, HA, Yunus, MB, et al.The American College of Rheumatology 1990 criteria for the classification of fibromyalgia. Arthritis Rheum. 1990;33(2):160–172.Google Scholar
3.Jain, AK, Carruthers, BM, van de Sande, MI, et al.Fibromyalgia syndrome: Canadian clinical working case definition, diagnostic, and treatment protocols—a consensus document. J Musculoske Pain. 2003;11(4):3–118.Google Scholar
4.Russell, IJ. A new journal. J Musculoske Pain. 1993;1(1):1–7.Google Scholar
5.Harden, RN, Bruehl, SP, Gass, S, Niemiec, C, Barbick, B. Signs and symptoms of the myofascial pain syndrome: a national survey of pain management providers. Clin J Pain. 2000;16(1):64–72.Google Scholar
6.Simons, DG, Travell, JG, Simons, LS. Myofascial Pain and Dysfunction: The Trigger Point Manual, Vol 1. Upper Half of Body. 2nd ed. Baltimore, MD: Williams & Wilkins; 1999.Google Scholar
7.Park, DC, Glass, JM, Minear, M, Crofford, LJ. Cognitive function in fibromyalgia patients. Arthritis Rheum. 2001;44(9):2125–2133.Google Scholar
8.Buckelew, SP, Huyser, B, Hewett, JE, et al.Self-efficacy predicting outcome among fibromyalgia subjects. Arthritis Care Res. 1996;9(2):97–104.Google Scholar
9.Tunks, E, McCain, GA, Hart, LE, et al.The reliability of examination for tenderness in patients with myofascial pain, chronic fibromyalgia and controls. J Rheumatol. 1995;22(5):944–952.Google Scholar
10.White, KP, McCain, GA, Tunks, E. The effects of changing the painful stimulus upon dolorimetry scores in patients with fibromyalgia. J Musculoske Pain. 1993;1(1):43–58.Google Scholar
11.Wolfe, F, Ross, K, Anderson, J, Russell, IJ, Hebert, L. The prevalence and characteristics of fibromyalgia in the general population. Arthritis Rheum. 1995;38(1):19–28.Google Scholar
12.Buskila, D. Fibromyalgia in children—lessons from assessing nonarticular tenderness. J Rheumatol. 1996;23(12):2017–2019.Google Scholar
13.Wolfe, F, Anderson, J, Harkness, D, et al.A prospective,longitudinal, multicenter study of service utilization and costs in fibromyalgia. Arthritis Rheum. 1997;40(9):1560–1570.Google Scholar
14.Buskila, D, Neumann, L, Vaisberg, G, Alkalay, D, Wolfe, F. Increased rates of fibromyalgia following cervical spine injury. A controlled study of 161 cases of traumatic injury. Arthritis Rheum. 1997;40(3):446–452.CrossRefGoogle ScholarPubMed
15.Pettersson, K, Karrholm, J, Toolanen, G, Hildingsson, C. Decreased width of the spinal canal in patients with chronic symptoms after whiplash injury. Spine. 1995; 20(15):1664–1667.CrossRefGoogle ScholarPubMed
16.Giovengo, SL, Russell, IJ, Larson, AA. Increased concentrations of nerve growth factor (NGF. in cerebrospinal fluid of patients with fibromyalgia. J Rheumatol. 1999; 26(7):1564–1569.Google Scholar
17.Boisset-Pioro, MH, Esdaile, JM, Fitzcharles, MA. Sexual and physical abuse in women with fibromyalgia syndrome. Arthritis Rheum. 1995;38(2):235–241.Google Scholar
18.Walker, EA, Keegan, D, Gardner, G, Sullivan, M, Bernstein, D, Katon, WJ. Psychosocial factors in fibromyalgia compared with rheumatoid arthritis: II. Sexual, physical, and emotional abuse and neglect. Psychosom Med. 1997;59(6):572–577.Google Scholar
19.Imbierowicz, K, Egle, UT. Childhood adversities in patients with fibromyalgia and somatoform pain disorder. European J Pain. 2003;7(2):113–119.Google Scholar
20.Taylor, ML, Trotter, DR, Csuka, ME. The prevalence of sexual abuse in women with fibromyalgia. Arthritis Rheum. 1995;38(2):229–234.Google Scholar
21.Castro, I, Barrantes, F, Tuna, M, et al.Prevalence of abuse in fibromyalgia and other rheumatic disorders at a specialized clinic in rheumatic diseases in Guatemala City. J Clin Rheumatol. 2005;11(3):140–145.Google Scholar
22.Goldberg, RT, Pachas, WN, Keith, D. Relationship between traumatic events in childhood and chronic pain. Disabil Rehabil. 1999;21(1):23–30.Google Scholar
23.Raphael, KG, Chandler, HK, Ciccone, DS. Is childhood abuse a risk factor for chronic pain in adulthood? Curr Pain Headache Rep. 2004;8(2):99–110.CrossRefGoogle ScholarPubMed
24.Finestone, HM, Stenn, P, Davies, F, Stalker, C, Fry, R, Koumanis, J. Chronic pain and health care utilization in women with a history of childhood sexual abuse. Child Abuse Negl. 2000;24(4):547–556.Google Scholar
25.Gamez-Nava, JI, Gonzalez-Lopez, L, Davis, P, Suarez-Almazor, ME. Referral and diagnosis of common rheumatic diseases by primary care physicians. Brit J Rheumatol. 1998;37(11):1215–1219.Google Scholar
26.Cohen, P, Cohen, J. The clinician’s illusion. Arch Gen Psychiatry. 1984;41(12):1178–1182.Google Scholar
27.Ciccone, DS, Elliott, DK, Chandler, HK, Nayak, S, Raphael, KG. Sexual and physical abuse in women with fibromyalgia syndrome: a test of the trauma hypothesis. Clin J Pain. 2005;21(5):378–386.Google Scholar
28.Alexander, RW, Bradley, LA, Alarcon, GS, et al.Sexual and physical abuse in women with fibromyalgia: association with outpatient health care utilization and pain medication usage. Arthritis Care Res. 1998;11(2):102–115.Google Scholar
29.Williams, LM. Recall of childhood trauma: a prospective study of women’s memories of child sexual abuse. J Consult Clin Psychol. 1994;62(6):1167–1176.Google Scholar
30.Widom, CS, Morris, S. Accuracy of adult recollections of childhood victimization, Part 2: Childhood sexual abuse. Psychol Assessment. 1997;9(1):34–46.CrossRefGoogle Scholar
31.Fergusson, DM, Horwood, LJ, Woodward, LJ. The stability of child abuse reports: a longitudinal study of the reporting behaviour of young adults. Psychol Med. 2000;30(3):529–544.Google Scholar
32.Hepp, U, Gamma, A, Milos, G, et al.Inconsistency in reporting potentially traumatic events. Brit J Psychiatry. 2006;188:278–283.Google Scholar
33.Raphael, KG, Cloitre, M, Dohrenwend, BP. Problems of recall and misclassification with checklist methods of measuring stressful life events. Health Psychol. 1991;10(1):62–74.Google Scholar
34.Raphael, K. Recall bias: a proposal for assessment and control. Int J Epidemiol. 1987;16(2):167–170.Google Scholar
35.Raphael, KG, Cloitre, M. Does mood-congruence or causal search govern recall bias? A test of life event recall. J Clin Epidemiol. 1994;47(5):555–564.Google Scholar
36.Raphael, KG, Widom, CS, Lange, G. Childhood victimization and pain in adulthood: a prospective investigation. Pain. 2001;92(1-2):283–293.Google Scholar
37.Brown, J, Berenson, K, Cohen, P. Documented and self-reported child abuse and adult pain in a community sample. Clin J Pain. 2005;21(5):374–377.Google Scholar
38.Widom, CS. Posttraumatic stress disorder in abused and neglected children grown up. Am J Psychiatry. 1999;156(8):1223–1229.Google Scholar
39.Raphael, KG, Janal, MN, Nayak, S. Comorbidity of fibromyalgia and posttraumatic stress disorder symptoms in a community sample of women. Pain Medicine. 2004;5(1):33–41.Google Scholar
40.Raphael, KG, Natelson, BH, Janal, MN, Nayak, S. A community-based survey of fibromyalgia-like pain complaints following the World Trade Center terrorist attacks. Pain. 2002;100(1-2):131–139.CrossRefGoogle ScholarPubMed
41.Yehuda, R, McFarlane, AC. Conflict between current knowledge about posttraumatic stress disorder and its original conceptual basis. Am J Psychiatry. 1995;152(12):1705–1713.Google Scholar
42.Buskila, D, Neumann, L. Genetics of fibromyalgia. Curr Pain Headache Rep. 2005;9(5):313–315.Google Scholar
43.Ebstein, RP, Buskila, D, Cohen, H, Neumann, L. An association between FMS and the serotonin transporter promoter region (5-HTTLPR)polymorphism and relationship to anxiety-related personality traits. Am J Med Genet. 2001;627:105.Google Scholar
44.Offenbaecher, M, Bondy, B, de Jonge, S, et al.Possible association of fibromyalgia with a polymorphism in the serotonin transporter gene regulatory region. Arthritis Rheum. 1999;42(11):2482–2488.Google Scholar
45.Caspi, A, Sugden, K, Moffitt, TE, et al.Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science. 2003;301(5631):386–389.Google Scholar
46.Arnold, LM, Hudson, JI, Hess, EV, et al.Family study of fibromyalgia. Arthritis Rheum. 2004;50(3):944–952.Google Scholar
47.Raphael, KG, Janal, MN, Nayak, S, Gallagher, RM, Schwartz, JE. Familial aggregation of depression in fibromyalgia: a community-based test of alternate hypotheses. Pain. 2004;110:449–460.Google Scholar