Hostname: page-component-84b7d79bbc-c654p Total loading time: 0 Render date: 2024-07-27T18:15:43.778Z Has data issue: false hasContentIssue false

Health Care System Changes to Improve Adherence and Long-Term Outcomes for Depressed Patients

Published online by Cambridge University Press:  07 November 2014

Extract

Depression, which is increasingly regarded as a chronic condition, is associated with significant suffering, social and functional impairment, and an estimated $44 billion in direct and indirect costs annually in the United States. Despite this severe burden on the health care system, the management of depression remains suboptimal in primary care, where many depressed patients fail to receive adequate dosage and duration of treatment. Adherence to evidence-based guidelines, essential to improving outcomes, requires key structural changes to the US health care delivery system. Several health care models aimed at improving treatment adherence in patients with chronic illnesses have been evaluated in primary care settings with promising results. Those approaches that have been found to be effective advocate multifaceted collaborative interventions that target patients, families, physicians, and the organization of the health care system to improve adherence and depression outcomes. Enhancing education and the active participation of patients and their families are now considered important elements of interventions to improve adherence to the treatment of chronic illnesses, including depression.

Type
Clinical Information Supplement
Copyright
Copyright © Cambridge University Press 2007

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Boland, RJ, Keller, MB. The course of depression. In: Davis, KL, Charney, D, Coyle, JT, Nemeroff, C, eds. Neuropsychopharmacology: The Fifth Generation of Progress. Lippincott Williams & Wilkins; 2002.Google Scholar
2.Badamgarav, E, Weingarten, SR, Henning, JM et al. , Effectiveness of disease management programs in depression: a systematic review. Am J Psychiatry. 2003;160:20802090.Google Scholar
3.Young, AS, Klap, R, Sherbourne, CD, Wells, KB. The quality of care for depressive and anxiety disorders in the United States. Arch Gen Psychiatry. 2001;58:5561.CrossRefGoogle ScholarPubMed
4.Simon, GE, Von Korff, M.Recognition, management, and outcomes of depression in primary care. Arch Fam Med. 1995;4:99105.CrossRefGoogle ScholarPubMed
5.Katon, W, Von Korff, M, Lin, E et al. , Collaborative management to achieve treatment guidelines. Impact on depression in primary care. JAMA. 1995;273:10261031.CrossRefGoogle ScholarPubMed
6.Berwick, DM. A user's manual for the IOM's ‘Quality Chasm’ report. Health Aff (Millwood). 2002;21:8090.CrossRefGoogle ScholarPubMed
7.Institute of Medicine. Crossing the Quality Chasm: A New Health System for the 21st Century. Washington DC: National Academy Press; 2001.Google Scholar
8.Von Korff, M, Gruman, J, Schaefer, J, Curry, SJ, Wagner, EH. Collaborative management of chronic illness. Ann Intern Med. 1997;127:10971102.CrossRefGoogle ScholarPubMed
9.Katon, W, Robinson, P, Von Korff, M et al. , A multifaceted intervention to improve treatment of depression in primary care. Arch Gen Psychiatry. 1996;53:924932.CrossRefGoogle ScholarPubMed
10.Frank, E, Kupfer, DJ, Siegel, LR. Alliance not compliance: a philosophy of outpatient care. J Clin Psychiatry. 1995;56(Suppl 1):1116.Google Scholar
11.Partnership for Solutions: Better Lives for People with Chronic Conditions. Available at: http://www.partnershipforsolutions.org/statistics/prevalence.html. Accessed December 19, 2006.Google Scholar
12.Hoyert, DL, Heron, MP, Murphy, SL, Kung, HC. Deaths: final data for 2003. Natl Vital Stat Rep. 2006;54:1120.Google ScholarPubMed
13.Druss, BG, Rosenheck, RA, Sledge, WH. Health and disability costs of depressive illness in a major U.S. corporation. Am J Psychiatry. 2000;157:12741278.CrossRefGoogle Scholar
14.Ustun, TB, Ayuso-Mateos, JL, Chatterji, S, Mathers, C, Murray, CJ. Global burden of depressive disorders in the year 2000. Br J Psychiatry. 2004;184:386392.CrossRefGoogle ScholarPubMed
15.Patten, SB. Long-term medical conditions and major depression in the Canadian population. Can J Psychiatry. 1999;44:151157.CrossRefGoogle ScholarPubMed
16.Iosifescu, DV, Bankier, B, Fava, M. Impact of medical comorbid disease on antidepressant treatment of major depressive disorder. Curr Psychiatry Rep. 2004;6:193201.CrossRefGoogle ScholarPubMed
17.Lustman, PJ, Clouse, RE. Depression in diabetic patients: the relationship between mood and glycemic control. J Diabetes Complications. 2005;19:113122.Google Scholar
18.Rubin, RR, Ciechanowski, P, Egede, LE, Lin, EH, Lustman, PJ. Recognizing and treating depression in patients with diabetes. Curr Diab Rep. 2004;4:119125.CrossRefGoogle ScholarPubMed
19.Lustman, PJ, Griffith, LS, Clouse, RE. Depression in adults with diabetes. Results of 5-yr follow-up study. Diabetes Care. 1988;11:605612.CrossRefGoogle ScholarPubMed
20.Katon, WJ. Clinical and health services relationships between major depression, depressive symptoms, and general medical illness. Biol Psychiatry. 2003;54:216226.CrossRefGoogle ScholarPubMed
21.Katon, W, Ciechanowski, P. Impact of major depression on chronic medical illness. J Psychosom Res. 2002;53:859863.CrossRefGoogle ScholarPubMed
22.Katon, WJ, Rutter, C, Simon, G et al. , The association of comorbid depression with mortality in patients with type 2 diabetes. Diabetes Care. 2005;28:26682672.Google Scholar
23.DiMatteo, MR, Lepper, HS, Croghan, TW. Depression is a risk factor for non-compliance with medical treatment: meta-analysis of the effects of anxiety and depression on patient adherence. Arch Intern Med. 2000;160:2101–7.Google Scholar
24.Katon, WJ, Lin, E, Russo, J, Unutzer, J. Increased medical costs of a population-based sample of depressed elderly patients. Arch Gen Psychiatry. 2003;60:897903.Google Scholar
25.Simon, GE, Katon, WJ, Lin, EH et al. Diabetes complications and depression as predictors of health service costs. Gen Hosp Psychiatry. 2005;27:344351.Google Scholar
26.Ferketich, AK, Schwartzbaum, JA, Frid, DJ, Moeschberger, ML. Depression as an antecedent to heart disease among women and men in the NHANES I study. National Health and Nutrition Examination Survey. Arch Intern Med. 2000;160:12611268.CrossRefGoogle ScholarPubMed
27.Frank, RG, Huskamp, HA, Pincus, HA. Aligning incentives in the treatment of depression in primary care with evidence-based practice. Psychiatr Serv. 2003;54:682687.CrossRefGoogle ScholarPubMed
28.Katon, W, Von Korff, M, Lin, E, Bush, T, Ormel, J. Adequacy and duration of anti-depressant treatment in primary care. Med Care. 1992;30:6776.CrossRefGoogle Scholar
29.Simon, GE, Von Korff, M, Wagner, EH, Barlow, W. Patterns of antidepressant use in community practice. Gen Hosp Psychiatry. 1993;15:399408.CrossRefGoogle ScholarPubMed
30.Lin, EH, Von Korff, M, Katon, W et al. The role of the primary care physician in patients’ adherence to antidepressant therapy. Med Care. 1995;33:6774.Google Scholar
31.Wells, KB, Katon, W, Rogers, B, Camp, P. Use of minor tranquilizers and anti-depressant medications by depressed outpatients: results from the medical outcomes study. Am J Psychiatry. 1994;151:694700.Google Scholar
32.Katon, W, Von Korff, M, Lin, E et al. Population-based care of depression: effective disease management strategies to decrease prevalence. Gen Hosp Psychiatry. 1997;19:169178.Google Scholar
33.Callahan, CM, Hendrie, HC, Dittus, RS, Brater, DC, Hui, SL, Tierney, WM. Improving treatment of late life depression in primary care: a randomized clinical trial. J Am Geriatr Soc. 1994;42:839846.CrossRefGoogle ScholarPubMed
34.Von Korff, M, Katon, W, Bush, T et al. Treatment costs, cost offset, and cost-effectiveness of collaborative management of depression. Psychosom Med. 1998;60:143149.CrossRefGoogle ScholarPubMed
35.Lin, EH, Katon, WJ, Von Korff, M et al. Relapse of depression in primary care. Rate and clinical predictors. Arch Fam Med. 1998;7:443449.CrossRefGoogle ScholarPubMed
36.Wagner, EH, Austin, BT, Von Korff, M. Improving outcomes in chronic illness. Manag Care Q. 1996;4:1225.Google ScholarPubMed
37.Katon, W, Von Korff, M, Lin, E, Simon, G. Rethinking practitioner roles in chronic illness: the specialist, primary care physician, and the practice nurse. Gen Hosp Psychiatry. 2001;23:138144.Google Scholar
38.Katon, WJ. The Institute of Medicine “Chasm” report: implications for depression collaborative care models. Gen Hosp Psychiatry. 2003;25:222229.CrossRefGoogle ScholarPubMed
39.Von Korff, M, Katon, W, Unutzer, J, Wells, K, Wagner, EH. Improving depression care: barriers, solutions, and research needs. J Fam Pract. 2001;50:E1.Google Scholar
40.Kobak, KA, Taylor, L, Katzelnick, DJ, Olson, N, Clagnaz, P, Henk, HJ. Antidepressant medication management and Health Plan Employer Data Information Set (HEDIS) criteria: reasons for nonadherence. J Clin Psychiatry. 2002;63:727732.CrossRefGoogle ScholarPubMed
41.Clinical Practice Guideline No. 5: Depression in Primary Care, 2: Treatment of Major Depression. Rockville, Md: Agency for Health Care and Policy Research, US Depart of Health and Human Services, 1993. AHCPR publication 93–0551.Google Scholar
42.Katon, W, Von Korff, M, Lin, E et al. , Stepped collaborative care for primary care patients with persistent symptoms of depression: a randomized trial. Arch Gen Psychiatry. 1999;56:11091115.CrossRefGoogle ScholarPubMed
43.Peveler, R, George, C, Kinmonth, AL, Campbell, M, Thompson, C. Effect of anti-depressant drug counselling and information leaflets on adherence to drug treatment in primary care: randomised controlled trial. BMJ. 1999;319:612615.CrossRefGoogle Scholar
44.Hunkeler, EM, Meresman, JF, Hargreaves, WA et al. , Efficacy of nurse tele-health care and peer support in augmenting treatment of depression in primary care. Arch Fam Med. 2000;9:700708.CrossRefGoogle Scholar
45.Katzelnick, DJ, Simon, GE, Pearson, SD et al. , Randomized trial of a depression management program in high utilizers of medical care. Arch Fam Med. 2000;9:345351.CrossRefGoogle ScholarPubMed
46.Wells, KB, Sherbourne, C, Schoenbaum, M et al. , Impact of disseminating quality improvement programs for depression in managed primary care: a randomized controlled trial. JAMA. 2000;283:212220.CrossRefGoogle ScholarPubMed
47.Rost, K, Nutting, P, Smith, J, Werner, J, Duan, N. Improving depression outcomes in community primary care practice: a randomized trial of the quEST intervention. Quality Enhancement by Strategic Teaming. J Gen Intern Med. 2001;16:143149.CrossRefGoogle ScholarPubMed
48.Simon, GE, Von Korff, M, Rutter, C, Wagner, E. Randomised trial of monitoring, feedback, and management of care by telephone to improve treatment of depression in primary care. BMJ. 2000;320:550554.CrossRefGoogle ScholarPubMed
49.Dietrich, AJ, Oxman, TE, Williams, JW Jr. et al. Re-engineering systems for the treatment of depression in primary care: cluster randomised controlled trial. BMJ. 2004;329:602.Google Scholar
50.Unutzer, J, Katon, W, Callahan, CM et al. , Collaborative care management of late-life depression in the primary care setting: a randomized controlled trial. JAMA. 2002;288:28362845.Google Scholar
51.Katon, W, Von Korff, M, Lin, E et al. , Improving primary care treatment of depression among patients with diabetes mellitus: the design of the pathways study. Gen Hosp Psychiatry. 2003;25:158168.CrossRefGoogle ScholarPubMed
52.Mulsant, BH, Alexopoulos, GS, Reynolds, CF III et al. , Pharmacological treatment of depression in older primary care patients: the PROSPECT algorithm. Int J Geriatr Psychiatry. 2001;16:585592.CrossRefGoogle Scholar
53.Alexopoulos, GS, Katz, IR, Bruce, ML et al. , Remission in depressed geriatric primary care patients: a report from the PROSPECT study. Am J Psychiatry. 2005;162:718724.Google Scholar
54.Katon, WJ, Von Korff, M, Lin, EH et al. , The Pathways Study: a randomized trial of collaborative care in patients with diabetes and depression. Arch Gen Psychiatry. 2004;61:10421049.CrossRefGoogle ScholarPubMed
55.Katon, W, Unutzer, J, Fan, MY et al. , Cost-effectiveness and net benefit of enhanced treatment of depression for older adults with diabetes and depression. Diabetes Care. 2006;29:265270.Google Scholar
56.Simon, G, Katon, W, Lin, EHB. Cost-effectiveness of systematic depression treatment among people with diabetes. Arch Gen Psychiatry. 2007;64:5672.CrossRefGoogle ScholarPubMed
57.Stewart, WF, Ricci, JA, Chee, E, Hahn, SR, Morganstein, D. Cost of lost productive work time among US workers with depression. JAMA. 2003;289:31353144.Google Scholar
58.Center for Prevention and Health Services. An employer's guide to behavioral health services. National Business Group on Health. 2005:1100.Google Scholar
59.Spinelli, RJ, Fromknecht, JM. Pay for performance: improving quality care. Health Care Manag (Frederick). 2007;26:128137.Google Scholar