We study the interplay between the minimal representations of the orthogonal Lie algebra
\mathfrak{g}=\mathfrak{so}(n+2,\mathbb{C}) and the algebra of symmetries
\mathscr{S}(\Box ^{r}) of powers of the Laplacian
\Box on
\mathbb{C}^{n}. The connection is made through the construction of a highest-weight representation of
\mathfrak{g} via the ring of differential operators
{\mathcal{D}}(X) on the singular scheme
X=(\mathtt{F}^{r}=0)\subset \mathbb{C}^{n}, for
\mathtt{F}=\sum _{j=1}^{n}X_{i}^{2}\in \mathbb{C}[X_{1},\ldots ,X_{n}]. In particular, we prove that
U(\mathfrak{g})/K_{r}\cong \mathscr{S}(\Box ^{r})\cong {\mathcal{D}}(X) for a certain primitive ideal
K_{r}. Interestingly, if (and only if)
n is even with
r\geqslant n/2, then both
\mathscr{S}(\Box ^{r}) and its natural module
{\mathcal{A}}=\mathbb{C}[\unicode[STIX]{x2202}/\unicode[STIX]{x2202}X_{n},\ldots ,\unicode[STIX]{x2202}/\unicode[STIX]{x2202}X_{n}]/(\Box ^{r}) have a finite-dimensional factor. The same holds for the
{\mathcal{D}}(X)-module
{\mathcal{O}}(X). We also study higher-dimensional analogues
M_{r}=\{x\in A:\Box ^{r}(x)=0\} of the module of harmonic elements in
A=\mathbb{C}[X_{1},\ldots ,X_{n}] and of the space of ‘harmonic densities’. In both cases we obtain a minimal
\mathfrak{g}-representation that is closely related to the
\mathfrak{g}-modules
{\mathcal{O}}(X) and
{\mathcal{A}}. Essentially all these results have real analogues, with the Laplacian replaced by the d’Alembertian
\Box _{p} on the pseudo-Euclidean space
\mathbb{R}^{p,q} and with
\mathfrak{g} replaced by the real Lie algebra
\mathfrak{so}(p+1,q+1).