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Comparison of oral sucrose and glucose electrolyte solutions in the out-patient management of acute gastroenteritis in infancy

Published online by Cambridge University Press:  15 May 2009

P. Hutchins ,
T. H. J. Matthews ,
J. E. Manly ,
B. Lawrie  and
J. A. Walker-smith
P. Hutchins
Affiliation:
Queen Elizabeth Hospital for Children, Hackney Road, London E2 8PS
T. H. J. Matthews
Affiliation:
Queen Elizabeth Hospital for Children, Hackney Road, London E2 8PS
J. E. Manly
Affiliation:
Queen Elizabeth Hospital for Children, Hackney Road, London E2 8PS
B. Lawrie
Affiliation:
Queen Elizabeth Hospital for Children, Hackney Road, London E2 8PS
J. A. Walker-smith*
Affiliation:
Queen Elizabeth Hospital for Children, Hackney Road, London E2 8PS
*
*Queen Elizabeth Hospital for Children, Hackney Road, London E2 8PS.
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Summary

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Seventy-three children under the age of 18 months presenting with acute gastroenteritis were given an electrolyte mixture with added sucrose or glucose in a randomized double-blind trial. The time taken to recovery in those successfully treated as out-patients was identical. However, of the 34 who received glucose, 11 (32%) required admission compared with 7 (18%) of the 39 who received sucrose. There was a wide range of osmolality of the made-up feeds, indicating inaccuracy in diluting the solutions as prescribed, but this did not in general correlate with need for admission.

Sucrose-electrolyte solution is at least as effective as a glucose-electrolyte solution for the out-patient management of acute gastroenteritis in infancy. The cheapness and easy availability of sucrose commends its use in developed and developing countries.

Type
Research Article
Information
Journal of Hygiene , Volume 82 , Issue 1 , February 1979 , pp. 15 - 19
Copyright
Copyright © Cambridge University Press 1979

References

REFERENCES

Chatterjee, A., Mahalanabis, D., Jalan, K. N., Maitra, T. K. & Agarwal, S. K. (1977). Evaluation of a sucrose/electrolyte solution for oral rehydration in acute infantile diarrhoea. Lancet i, 1333.CrossRefGoogle Scholar
Editorial (1975). Lancet i, 79.Google Scholar
Field, M. (1975). Regulation of active ion transport in the small intestine in Acute Diarrhoea in Childhood:. Ciba Foundation Symposium (new Series) no. 42, pp. 109–21.Google Scholar
Fordtran, J. S. (1975). Stimulation of active and passive sodium absorption by sugars in the human jejunum. Journal of Clinical Investigation 55, 728.CrossRefGoogle ScholarPubMed
Hirschhorn, N., McCarthy, B. J., Ranney, B., Hirschhorn, M. A., Wooward, S. T., Lacapar, A., Cash, R. A. & Woodward, W. E. (1973). Ad libitum oral glucose-electrolyte therapy for acute diarrhoea in Apache children. Journal of Paediatrics 83, 562.CrossRefGoogle ScholarPubMed
Moenginah, P. A., Suprapto, , Soenarto, J., Bachtin, M., Sutrisno, D. Sutaryo & Rohde, J. E. (1975). Oral sucrose therapy for diarrhoea. Lancet ii, 323.CrossRefGoogle Scholar
Nalin, D. R. (1975). Sucrose in oral therapy for cholera and related diarrhoea. Lancet i, 1400.CrossRefGoogle Scholar
Rahilly, P. M., Shepherd, R., Challis, D., Walker-Smith, J. A. J. (1976). Clinical comparison between glucose and sucrose additions to a basic electrolyte mixture in the outpatient management of acute gastroenteritis in children. Archives of Disease in Childhood 51, 152.CrossRefGoogle ScholarPubMed
Rohde, J. E. & Northrup, R. S. (1975). P. 341 in Acute Diarrhoea in Childhood. Ciba Foundation Symposium (new series) no. 42.Google Scholar
W.H.O. (1974). The ten leading causes of death from selected countries in North America, Europe and Oceanion, 1969, 1970, 1971. World Health Statistics Report 27, 563.Google Scholar