Hostname: page-component-77c89778f8-7drxs Total loading time: 0 Render date: 2024-07-24T11:48:49.676Z Has data issue: false hasContentIssue false

Four outbreaks of nosocomial systemic candidiasis

Published online by Cambridge University Press:  19 October 2009

J. P. Burnie
Affiliation:
St Bartholomew's Hospital Medical School, London
Ruth Matthews
Affiliation:
St Bartholomew's Hospital Medical School, London
Woei Lee
Affiliation:
St Bartholomew's Hospital Medical School, London
J. Philpott Howard
Affiliation:
King's College Hospital, London
N. Damani
Affiliation:
St Helier's Hospital, Carshalton
Ruth Brown
Affiliation:
Queen Elizabeth Hospital, Birmingham
Zoe Jordans
Affiliation:
The London Hospital Medical College
Rights & Permissions [Opens in a new window]

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Candida albicans has recently been described as a cause of nosocomial infection. This paper reports four further outbreaks occurring over a 12-month period in England. There were 13 systemic cases and 6 deaths. The outbreaks were defined by morphotyping andthe new technique of immunoblot fingerprinting. Controi of the outbreaks was produced bythe implementation of strict cross-infection control policies without recourse to systemic chemoprophylaxis.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1987

References

REFERENCES

Brown-Thomsen, .J. (1968). Variability in Candida albicans (Robin). Hereditas 60. 355398.CrossRefGoogle Scholar
Burnie, J. P., Odds, F. C, Lee, W., Webster, C.& Williams, J. D. (1985 a). Outbreak of systemic Candida albicans in intensive care unit caused by cross-infection. British Medical Journal 290, 746748.CrossRefGoogle ScholarPubMed
Burnie, J. P., Lee, W., Williams, L. D., Matthews, R. C.& ODDS, F.C. (1985 b). Control of an outbreak of systemic Candida albicans. British Medical Journal 291, 10921093.CrossRefGoogle ScholarPubMed
Cremer, G.& De Groot, W. P. (1067). An epidemic of thrush in a premature nursery. Dermatologia 135, 102114.Google Scholar
Hasenclever, H. F.& Mitchell, W. O. (1961). Antigenic studies of Candida. T. Observation of two antigenic groups in Candida albicans.Journal of Bacteriolgy 82, 570573.CrossRefGoogle Scholar
Hay, R. (1985). Ketoconazole: a reappraisal. British Medical Journal 290. 260261.CrossRefGoogle ScholarPubMed
Kasimur, J. M., Ayliffe, G. A. J.& George, R. H. (1980). The survival of Candida albicans in moist and dry environments. Journal of Hospital Infection 1. 349356.Google Scholar
Knittle, M. A., Eitzmam, D. V.& Baer, H. (1975).Role of hand contamination of personnel in the epidemiology of Gram negative nosocomial infection. Journal of Paediatrics 86 433–137.CrossRefGoogle Scholar
Lee, W., Burnie, J. P.& Matthews, R. C. (1986). Fingerprinting Candida albicans. Journal of Immunological Methods 93, 177182.CrossRefGoogle ScholarPubMed
Marples, R. R., Richardson, J. R., Seal, D. V.& Cooke, E. M. (1985). Adhesive tapes in the special care baby unit. Journal of Hospital Infection 6, 398405.Google Scholar
Malamatinis, J. E., Mattmiller, E. D.& Westfall, J. N. (1968). Cutaneous moniliasis affecting varsity athletes. Journal ofthe American College Health Association 16. 294295.Google Scholar
Odds, F. C.& Abbott, A. B. (1980). A simple system for the presumptive identification of Candida albicans and differentiation of strains within the species. Sabouraiidia 18. 301317.CrossRefGoogle ScholarPubMed
Phelps, M., Ayliffe, G. A. J. & Babb, J. R. (1986). An outbreak of candidiasis in a special care baby unitrthe use of resistogram typing method. Journal of Hospital Infection 7, 1320.Google Scholar