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The mechanism of the ‘Welsch phenomenon’
Published online by Cambridge University Press: 15 May 2009
Extract
The disappearance of the resistant mutant from an artificial mixture of normal antibiotic-sensitive organisms and a resistant mutant after varying numbers of subcultures is known as the Welsch phenomenon. Welsch's observations have been confirmed and experiments devised to show that the resistant strain disappears because it grows more slowly than the normal sensitive strain which eventually, during the successive subcultures, overgrows it.
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- Copyright © Cambridge University Press 1958
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