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A survey of trimethoprim resistance in the enteric bacterial flora of farm animals

Published online by Cambridge University Press:  15 May 2009

B. West  and
G. White
B. West
Affiliation:
Welcome Research Laboratories, Berkhamsted Hill, Berkhamsted, Herts
G. White
Affiliation:
Welcome Research Laboratories, Berkhamsted Hill, Berkhamsted, Herts
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Summary

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For 29 months the Veterinary Investigation Centres, covering the whole of Great Britain, forwarded trimethoprim-resistant gram negative enteric bacteria to the Wellcome Research Laboratories. These were examined for degree of resistance, presence and type of R factors. Trimethoprim resistance was found in 0·6 % of the total number of strains examined by the Veterinary Investigation Centres. Trimethoprim R factors were demonstrated in one quarter of the resistant strains, and R factors were found in two strains of Salmonella typhimurium. It was concluded that while the incidence of trimethoprim resistance revealed by the survey gave no cause for alarm, the detection of resistant strains, and particularly R factors, indicated that the drug should continue to be used only for specific therapeutic purposes.

Type
Research Article
Information
Journal of Hygiene , Volume 82 , Issue 3 , June 1979 , pp. 481 - 488
Copyright
Copyright © Cambridge University Press 1979

References

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