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Contemporary thinking about the role of genes and environment in eating disorders

Published online by Cambridge University Press:  11 October 2011

Cynthia M. Bulik  and
Federica Tozzi
Cynthia M. Bulik*
Affiliation:
Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC (USA)
Federica Tozzi
Affiliation:
Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC (USA)
*
Address for correspondence: Dr. C. Bulik, Department of Psychiatry, University of North Carolina at Chapel Hill, 1st floor Neurosciences Hospital, 101 Manning Drive, CB #7160, Chapel Hill, NC 27599-7160 (USA). Fax: +1-919-966.5628 E-mail: cbulik@med.unc.edu
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Summary

Objective – To review recent literature documenting how family, twin and molecular genetic studies of eating disorders have revolutionized our conceptualizations of anorexia and bulimia nervosa. Methods – We summarized extant litera-ture on genetic epidemiology of eating disorders. Results – Results of extant studies highlight the underlying biological vulnera- bilities associated with these conditions. Genetic research has also opened up new avenues and approaches for exploring how the environment exerts its influence on risk. Conclusions – We discuss state-of-the-science findings in the genetics of eating disorders, explore various mechanisms of gene-environment interplay, and discuss implications of this research for science, practice, families and individuals with eating disorders.

Type
Invited Papers
Information
Epidemiology and Psychiatric Sciences , Volume 13 , Issue 2 , June 2004 , pp. 91 - 98
Copyright
Copyright © Cambridge University Press 2004

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