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Estructura y función del cuerpo calloso en la esquizofrenia: ¿Cuál es la conexión?

Published online by Cambridge University Press:  12 May 2020

A. S. David ,
C. Minne ,
P. Jones ,
I. Harvey  and
M. A. Ron
A. S. David
Affiliation:
Departamento de Medicina Psicológica, King's College Hospital e Instituto de Psiquiatría, Londres
C. Minne
Affiliation:
Hospital Maudsley, Londres
P. Jones
Affiliation:
Departamento de Medicina Psicológica, King's College Hospital e Instituto de Psiquiatría, Londres
I. Harvey
Affiliation:
Departamento de Medicina Psicológica, King's College Hospital e Instituto de Psiquiatría, Londres Hospital Maudsley, Londres
M. A. Ron
Affiliation:
Instituto de Neurología, Queen Square, Londres, Reino Unido
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Resumen

Estudios de la estructura y función del cuerpo calloso han revelado anormalidades en pacientes esquizofrénicos. Una prueba funcional de este tipo empleó estímulos de Stroop lateralizados presentados taquistoscópicamente para medir la transferencia de interferencia y facilitación entre los hemisferios cerebrales. Se hizo un intento de relacionar índices de transferencia del cuerpo calloso con variables clínicas y demográficas, incluida la historia familiar, y con índices de morfología cerebral. Los últimos incluían la razón ventrículoxerebro (RVC) medida por tomografía computarizada (TC) en 31 esquizofrénicos según el DSMIII, y el área transversal del cuerpo calloso a partir de imágenes de resonancia magnética (IRM), obtenidas de 20 de estos pacientes. La RVC no estaba relacionada con medidas funcionales; sin embargo, el área anterior del cuerpo calloso tenía correlación con índices de conectividad del cuerpo calloso. Los pacientes con alucinaciones auditivas tenían el área anterior del cuerpo calloso más pequeña y tendían a mostrar menos conectividad. Los resultados muestran relaciones entre medidas funcionales y estructurales del cuerpo calloso, pero su naturaleza precisa es poco clara.

Type
Artículo original
Information
European Psychiatry (Ed. Española) , Volume 2 , Issue 3 , June 1995 , pp. 170 - 179
Copyright
Copyright © European Psychiatric Association 1995

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