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Factores que influyen en la investigación de los criterios de valoración de la depresión (FINDER): Diseño del studio y características de la población
Published online by Cambridge University Press: 01 May 2008
Resumen
Los factores que influyen en los resultados de depresión en la práctica clínica, sobre todo, la calidad de vida relacionada con la salud (CVRS), son relativamente desconocidos. El estudio de los Factores que Influyen en la Investigación de los Criterios de Valoración de la Depresión (FINDER) es un estudio europeo prospectivo de observación diseñado para estimar la CVRS de adultos con un episodio depresivo diagnosticado en la clínica inicialmente, y 3 y 6 meses después del comienzo del tratamiento antidepresivo. Describimos aquí el diseño del estudio y las características iniciales de los pacientes.
La CVRS se evaluó con el Cuestionario de Salud de 36 apartados (SF-36) y en el Cuestionario Europeo de Calidad de Vida de 5 Dimensiones (EQ-5D). También se determinaron las Puntuaciones de los pacientes en la Escala de Depresión, y Ansiedad Hospitalaria (HADS) y en la Escala Analógica Visual (EAV). Los resultados (n=3.468) demostraron que el resumen del componente mental del custionario SF-36 (media 22,2) estaba más de dos DE por debajo de la norma de la población general (media 50) y una DE por debajo de la norma de la depresión clínica (media 34,8); el resumen del componente físico (media 46,1) fue similar a la población general (media 50) y a la norma de depresión clínica (media 45). Las puntuaciones medias de EQ-5D eran tambien inferiores que la norma de la población general. Las puntuaciones medias de depresión y ansiedad de HADS eran 12,3 y 13, respectivamente. El 56% de los pacientes describió una puntuación total del dolor en la EAV de, al menos, 30 mm y el 70% de estos pacientes no tenía ninguna explicación física de su dolor.
Deben realizarse más investigaciones sobre los factores asociados con la CVRS en pacientes con depresión después de la iniciación del tratamiento.
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References
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