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Genética de la abstinencia del alcohol

Published online by Cambridge University Press:  12 May 2020

L G.Schmidt
Affiliation:
Departamento de Psiquiatría, Universidad Libre de Berlín, Eschenallee 3, 14050Berlín, Alemania
T. Sander
Affiliation:
Departamento de Psiquiatría, Universidad Libre de Berlín, Eschenallee 3, 14050Berlín, Alemania
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Resumen

La abstinencia del alcohol es un síndrome clínica y etiológicamente heterogéneo causado por una interacción compleja de factores ambientales (por ejemplo, la cantidad de etanol) y genéticos. Se considera que múltiples genes están implicados en diversos componentes del síndrome, contribu-yendo cada uno de ellos sólo de manera modesta a la abstinencia. Se revisan los estudios de asociación que han utilizado genes candidatos de los sistemas de dopamina, serotonina, gabaérgico y opioidérgico y se analizan las limitaciones metodológicas.

Type
Artículo original
Copyright
Copyright © European Psychiatric Association 2000

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References

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