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Clinico-psychopathological characteristics of patients with residual states in long-term schizophrenia

Published online by Cambridge University Press:  19 July 2023

V. Mitikhin*
Affiliation:
Department of Mental Health Support Systems Research Centre, Mental Health Research Centre, Moscow, Russian Federation
M. Kuzminova
Affiliation:
Department of Mental Health Support Systems Research Centre, Mental Health Research Centre, Moscow, Russian Federation
*
*Corresponding author.

Abstract

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Introduction

Long-term schizophrenia, even in remission, is necessarily accompanied by residual symptoms that may be quite pronounced and may significantly affect many aspects of the patient’s life, requiring exploration of specific therapeutic approaches. The alleviation of residual symptoms is an important factor in the patient’s better adjustment.

Objectives

Assessment and study clinical characteristics long-term schizophrenia.

Methods

Clinical, statistical, psychometric. A total of 90 patients, mean age 66,6±13,3 years, 26 males, 64 females were examined.

Results

Negative symptoms were predominant in patients with long-term schizophrenia (17,8±6,7). It was represented by: abstract thinking disorders (2,8±1,0), stereotyped thinking (2,7±1,1), passive-apathetic social isolation (2,6±1,2), avolition (2,6±0,8), flattening of affect (2,5±0,8). It manifested as lack of expressiveness in facial expressions and gestures, deficit of communicative gestures as well as emotional indifference (2,4±1,1), limitation of contacts with people, and spontaneous and fluent speech impairments. Positive symptoms were rare, mainly represented by suspiciousness (2,2±1,2), sometimes rising to delirium (1,8±1,4). Conceptual disorganization was detected in 1,9±0,7. Agitation and aggression were generally not characteristic of those surveyed. Depression/anxiety was quite pronounced in patients with long-term schizophrenia. Depression (1,8±0,8) was represented by low mood, hopelessness and loss of social interests. Anxiety (2,9±1,2) was even more prominent and predominant amongst all symptoms.

Conclusions

The authors expanded our understanding of the clinical characteristics of residual symptoms of long-term schizophrenia to allow timely identification and provision of medical and rehabilitative care.

Disclosure of Interest

None Declared

Type
Abstract
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2023. Published by Cambridge University Press on behalf of the European Psychiatric Association
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