The drug dependency are chronic disorders of enamel relapse resulting from the interaction between a living organism and a psychoactive substance.

The aim of our study is to evaluate the effectiveness of a comprehensive treatment plan for drug dependency at the center through drug addiction treatment using Annaba a semi-structured interview by direct multidimensional exploring different psychoactive substances.

Our methodology is based on an observational study of a cohort of 100 patients, aged 17 to 54, having a substance-related disorders according to DSM IV-TR, followed by the CIST Annaba since 2008.

The age group most affected is between 21–30 years, predominantly male (96%), singles (68%), inactive (58%) and residing in the region of Annaba (77%), duration average consumption is higher (10 + 3 years) in 33% of cases, poly drug at doses above therapeutic in 90% of cases. The personality assessment is made by the Rorschach projective test of objectifying the presence of borderline personality disorder in 68% of cases. The establishment of a therapeutic project (motivational interviewing, drug substitution treatment and symptomatic treatment with cognitive behavioral psychotherapy) of drug dependency at the CIST Annaba could positively reinforce the assumption by reducing or stopping use toxic products. Cases of remission were found in 48%, but relapse was concerned that a quarter of cases.