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Measuring quality of life in first-episode psychosis

Published online by Cambridge University Press:  16 April 2020

I. Melle ,
S. Friis ,
U. Haahr ,
J.O. Johannesen ,
T.K. Larsen ,
S. Opjordsmoen ,
J.I. Roessberg ,
B.R. Rund ,
E. Simonsen  and
P. Vaglum
...Show all authors
I. Melle*
Affiliation:
Department of Research and Education, Division of Psychiatry, Ullevål University Hospital, 0407Oslo, Norway Institute of Psychiatry, University of Oslo, Oslo, Norway
S. Friis
Affiliation:
Department of Research and Education, Division of Psychiatry, Ullevål University Hospital, 0407Oslo, Norway Institute of Psychiatry, University of Oslo, Oslo, Norway
U. Haahr
Affiliation:
Roskilde County Psychiatric Hospital Fjorden, Roskilde, Denmark
J.O. Johannesen
Affiliation:
Rogaland Psychiatric Hospital, Rogaland, Norway
T.K. Larsen
Affiliation:
Rogaland Psychiatric Hospital, Rogaland, Norway Institute of Psychiatry, University of Oslo, Oslo, Norway
S. Opjordsmoen
Affiliation:
Department of Research and Education, Division of Psychiatry, Ullevål University Hospital, 0407Oslo, Norway Institute of Psychiatry, University of Oslo, Oslo, Norway
J.I. Roessberg
Affiliation:
Department of Research and Education, Division of Psychiatry, Ullevål University Hospital, 0407Oslo, Norway
B.R. Rund
Affiliation:
Institute of Psychology, University of Oslo, Oslo, Norway
E. Simonsen
Affiliation:
Roskilde County Psychiatric Hospital Fjorden, Roskilde, Denmark
P. Vaglum
Affiliation:
Institute of Behavioral Sciences in Medicine, University of Oslo, Oslo, Norway
T. McGlashan
Affiliation:
Department of Psychiatry, Yale University, New Haven, CT, USA
*
*Corresponding author. Tel.: +47 2 21 18458; fax: +47 2 21 17848. E-mail address: ingrid.melle@medisin.uio.no (I. Melle).
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Abstract

Quality of life (QoL) measures are increasingly recognized as necessary parts of outcome assessments in psychosis. The present paper is a comprehensive study of patients with first-episode psychosis where QoL is measured by the commonly used Lehman Quality of Life Interview (L-QoLI). The aim is to examine if the L-QoLI maintain its original structure when used in a group of patients with first-episode psychosis, and to investigate what determines global subjective QoL with a specific emphasis on premorbid adjustment, duration of untreated psychosis (DUP) and clinical symptoms. The study indicates that the psychometric properties of the L-QoLI do not change significantly when used in first-episode samples. The patients report subjective and objective QoL in the fair to good range, with only a moderate association between the objective and subjective measures. Poor global satisfaction is predicted by being single, abusing drugs, being depressed, having a diagnosis of psychotic affective disorder, having poor premorbid social adjustment and DUP over 10 weeks. The study supports the notion that patients with first-episode psychosis construct QoL in the same way as other groups, and that longer durations of compromised function at this stage produces poor satisfaction with life rather than a downward readjustment of expectations.

Keywords

SchizophreniaAffective psychosisFirst-episode psychosisQuality of lifePremorbid adjustment
Type
Original article
Information
European Psychiatry , Volume 20 , Issue 7 , November 2005 , pp. 474 - 483
Copyright
Copyright © Elsevier SAS 2005

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