The proposal It's been to describe by an oral presentation, a five cases of Mexican women that have the Schizophrenia diagnosis and that were treated with Sertindol (Serlect) between the months of October 2007 to September 2008, one of them were an Subtype disorganized, other one was Paranoid Subtype and the others were and Indiferential continuous subtype, all of them had an early response on the management of the negative and positive symptoms and also recovered cognitive functions in less time using Sertindol than other antipsychotics treatments. Every one participated on a protocol's study with clinical scales like PANSS, BPRS, and had preclinical studies every 2 weeks by the first 2 months and every 4 weeks by the rest of the time.