The symptoms of multiple sclerosis are varied and can occur suddenly, then disappear again just as quickly. There are no specific sets of symptoms; it tends to vary considerably from one person to another and also to be distant in time.

As well as a range of different physical symptoms, multiple sclerosis can also cause a wide variety of mental and emotional disturbances.

Psychosis in multiple sclerosis, while not common, does occur in approximately 5% of cases, although it is probably under reported.

Neurological changes, alterations in brain chemistry or severe stress such as that brought on by diagnosis or the impact of multiple sclerosis, can lead to the development of psychosis

Psychosis may also occur as a result of treatment with steroids or other drugs.

The duration and intensity of the psychotic episode can be variable, ranging from mild loss of contact with reality, to severe loss of a grasp on reality, with full delusional episodes; to complete catatonia.

We present a case report of a patient diagnosed with Multiple Scleroses that presents psychotic symptoms as early symptomatology of the disease, independently of steroid and other specifically medication.