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Personality disorders and affective temperament in unipolar and bipolar mood disorder

Published online by Cambridge University Press:  23 March 2020

A. Nivoli ,
L. Floris ,
M. Antonioli ,
L. Folini ,
L.F. Nivoli ,
P. Milia ,
L.I. Vento ,
C. Depalmas  and
L. Lorettu
L. Floris
Affiliation:
University of Sassari, Department of Psychiatry, Sassari, Italy
M. Antonioli
Affiliation:
University of Sassari, Department of Psychiatry, Sassari, Italy
L. Folini
Affiliation:
University of Sassari, Department of Psychiatry, Sassari, Italy
L.F. Nivoli
Affiliation:
University of Sassari, Department of Psychiatry, Sassari, Italy
P. Milia
Affiliation:
University of Sassari, Department of Psychiatry, Sassari, Italy
L.I. Vento
Affiliation:
University of Sassari, Department of Psychiatry, Sassari, Italy
C. Depalmas
Affiliation:
University of Sassari, Department of Psychiatry, Sassari, Italy
L. Lorettu
Affiliation:
University of Sassari, Department of Psychiatry, Sassari, Italy

Abstract

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Introduction

Personality disorders (PD) and Affective temperaments (AT) have been considered vulnerability factors for the development of mood disorder (MD).

Objective

To study the simultaneous presence of PD and AT in patients with DU and differences between unipolar depression (DD) and bipolar disorder BD.

Methods

An observational study was conducted. Patients were administered the Temperament Evaluation of Memphis, Pisa, Paris and San Diego questionnaire (TEMPS-A) for AT and the Structured Clinical Interview for DSM IV Axis II Disorders (SCID-II) for PD. The interrelationships of the different PD and AT were studied by factor analysis (principal component analysis, PCA) (orthogonal rotation, Varimax).

Results

Participants were 156 adult patients with MD, 37.1% with DD and 62.9% with BD. DD patients presented with significantly more paranoid PD (P = 0.009), depressive (P = 0.029), anxious (P = 0.009) and irritable temperament (P = 0.006) compared to BD. PCA results showed four significant factors, explaining the 63.1% of total variance, corresponding to four potential groups of patients with specific PD and AT associations.

Conclusion

The comorbidity between MD and PD and AT may differentiate DD from BD. Specific patterns of comorbidity may be useful as they may substantially influence the course of the mood disorders and how patients respond to treatment.

Disclosure of interest

The authors have not supplied their declaration of competing interest.

Type
e-Poster viewing: Cultural psychiatry
Information
European Psychiatry , Volume 41 , Issue S1: Abstract of the 25th European Congress of Psychiatry , April 2017 , pp. S536
Copyright
Copyright © European Psychiatric Association 2017
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