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Psychosis: Risk Factors and Prognosis

Published online by Cambridge University Press:  01 September 2022

M. Fernández Lozano*
Affiliation:
Hospital Clínico de Valladolid, Psychiatry, Valladolid, Spain
I. Santos Carrasco
Affiliation:
Clinical Hospital of Valladolid, Psychiatry, Valladolid, Spain
B. Rodríguez Rodríguez
Affiliation:
Hospital Clínico Universitario, Psiquiatría, Valladolid, Spain
N. Navarro Barriga
Affiliation:
Hospital Clínico Universitario de Valladolid, Psiquiatría, VALLADOLID, Spain
M.J. Mateos Sexmero
Affiliation:
Hospital Clínico Universitario, Psiquiatría, Valladolid, Spain
T. Jiménez Aparicio
Affiliation:
Hospital Clínico Universitario, Psiquiatría, Valladolid, Spain
C. De Andrés Lobo
Affiliation:
Hospital Clínico Universitario de Valladolid, Psiquiatría, VALLADOLID, Spain
C. Vallecillo Adame
Affiliation:
Hospital Clínico Universitario, Psiquiatría, Valladolid, Spain
M. Queipo De Llano De La Viuda
Affiliation:
Hospital Clínico Universitario, Psiquiatría, Valladolid, Spain
G. Guerra Valera
Affiliation:
Hospital Clínico Universitario, Psiquiatría, Valladolid, Spain
A. Gonzaga Ramírez
Affiliation:
Hospital Clínico Universitario, Psiquiatría, Valladolid, Spain
J. Gonçalves Cerejeira
Affiliation:
Hospital Clínico Universitario de Valladolid, Psychiatry, Valladolid, Spain
O. Segurado Martín
Affiliation:
Clinical Hospital of Valladolid, Psychiatry, Valladolid, Spain
*
*Corresponding author.

Abstract

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Introduction

There are life events that may increase the possibilities of suffering some kind of Psychopathology. The most validated model for understanding the aetiology of psychosis is based on genetic and environmental risk factors and their interaction, likely involving epigenetic mechanisms. It is necessary to consider those events as risk factors for Mental Health.

Objectives

Study of risk and prognostic factors in psychosis.

Methods

Review of scientific literature based on a relevant clinical case.

Results

We present the case of a 28-year-old male patient from Peru, currently living in Germany. History of sexual abuse in childhood. He started taking drugs at the age of 8. In the emergency department, he reports that since the beginning of the pandemic, after listening to a speech by the Pope, he begins to interpret signals about situations occurring around him. He begins to read about mystical-religious subjects, changes the style of music he listens to and recognises changes in his personality. He says for months he has been feeling watched, persecuted and expresed someone wants to kill him. He says hears voices and that they communicate with him through bodily sensations.

Conclusions

Childhood trauma, immigration and cannabis use are significantly associated with an increased risk of functional psychosis. A neurotic personality also independently contributes to this risk. The accumulation of these factors increases vulnerability to mental disorders and leads to a worse prognosis and evolution of these pathologies. These findings could help to improve the prevention of psychosis and the development of specific treatment strategies in this particular population.

Disclosure

No significant relationships.

Type
Abstract
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2022. Published by Cambridge University Press on behalf of the European Psychiatric Association
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