Despite the delay accumulated in their implementation, France actually develops a growing interest in early detection (ED) and early intervention (EI) services. The French network of Maisons des Adolescents (Adolescents’ Houses) offer various advantages for ED/EI. Adolescent’s houses are dedicated to prevention, health promotion and orientation to specific care of young people between 11 and 25. French government has developed a territorial coverage of these centres since 2005, and 111 Adolescents’ Houses are actually implemented all over the country. The CLIP (Centre de Liaison et d’Intervention Précoce) has been developed in the Adolescents’ House of Nancy (East of France). This centre offers evaluation and care for young people with an At Risk Mental State for Psychosis or a non medicated First Episode of Psychosis. Such a partnership provides clear benefits for ED/EI approach, but has to be adapted to Adolescents’ House constraints.

Existing guidelines for first episode psychosis recommend identification and timely treatment of first-episode psychosis patients through specific early intervention programmes. Most guidelines also highlight the importance of family intervention to prevent relapse. The first episode psychosis integrative treatment programme in Tallinn, Estonia was established in 1997. The programme stems from the need-adapted model developed by Yrjö O. Alanen in Finland. The integrative family-centered team approach can be described by different levels: integration of different treatment modalities, inpatient and outpatient treatment, different specialities in a multiprofessional team and integration of multilevel expertise involving families. The efficacy of the integrative treatment model was investigated in a two-year follow-up. The study showed that patients in the programme had improved quality of life and employment rates after two years. This model is being used today with the same core features and with some new approaches included over the years. The aim of this presentation is to provide an introduction to the integrative family-centered team model and the psychotherapeutic and psychosocial interventions used in The First Episode Psychosis Integrative Treatment Department in Tallinn Psychiatry Clinic.

Three aspects will be discussed which are considered relevant for preventing suicidal behaviour: 1) Media coverage of suicides can induce not only acute increases in suicides via the well-known Werther-effect but also long-lasting changes in suicidal behaviour. Increasing cognitive availability for certain suicide methods is a possible explanation for this long-lasting effect (Hegerl et al 2013, J Affect Dis). 2) Rapid propagation of informations about certain suicide methods (e.g. carbomonoxide via charcoal burning) influences the choice of suicide methods and the lethality of suicidal acts with major impact on suicide rates. It will be discussed whether increases in suicide rates for younger people and females observed in some countries are explained by an increased lethality of suicidal intoxications due to social media effects. 3) Suicide preventive campaigns are likely to improve help seeking behaviour but also to lower threshhold by normalizing suicidal behaviour. The balance between these two effects is unclear and will be discussed.

Evidence for efficacy of psychotherapies growing and the inclusion of such therapies in international guidelines for treatment of psychiatric disorders is increasing as well. Here, we present a cross sectional survey conducted by the EFPT psychotherapy working group in 2013-2015 and published in European Psychiatry journal. 574 professionals from 22 European countries answered online. 92% of trainees considered psychotherapy as important for their professional identity. 90% would like to practice psychotherapy after their training. 96 % would train for free. 50 % intend to spend up to 5 % of their salary for psychotherapy training. Psychoanalysis, CBT and Systemic Therapy were the most popular schools of psychotherapy. For most trainees, only theoretical lectures are mandatory. Whereas training in psychotherapy is recommended by UEMS as a mandatory component of curriculum, most trainees don’t receive any or need to pay for it. Recommendations of UEMS are reported to be implemented in 22% of respondents’ country of origin. Less than 50 % of participants received a training in psychotherapy. 33 % undertook psychotherapy training on their own initiative. Whereas more than 1.7 hours of supervision per month are recommended by UEMS. 50 % don’t get any hour during the month. Related survey are conducted at the moment by the World Psychiatrist Association and the EFPT Child and Adolescent working group to confirm and precise this data. From this assessment, EFPT and EPA proposed different initiatives to improve this training: online ressources e-training, MOOC, journal club, psychotherapy guidebook. http://efpt.eu/wp-content/uploads/2019/01/psychotherapy.pdf

There are so many kinds of psychotherapies out there and what better way to explain and discuss them in a peer-to-peer relationship than a trainee exchanging ideas about experiences in the particular therapy with a fellow trainee.

It all started in London in 2014, when some colleagues from our EFPT group started to discuss the idea of creating a free guidebook on Psychotherapy written by trainees for trainees. The idea travelled across Europe along with the members of our group. It expanded and evolved year after year, from forum to forum, when finally, the time had come to return to the UK, in Bristol this time, in 2018 with its first edition of our free EFPT psychotherapy guidebook. This year we also updated a mobile friendly version of it on a web authoring platform. The 1st edition contained 12 chapters. Our psychotherapy working group has expanded and together with the increase in the number of our members, we managed to double the number of chapters of our psychotherapy guidebok.

The goal is for each chapter to be written by trainees who have had experience or interest in that particular psychotherapy. There are many psychotherapies that we have not included yet in our guidebook that are looking for authors, contributors! Let’s all put some effort to make our next versions of our Psychotherapy guidebook a valuable gift to our younger colleagues who are choosing their path and to all of us who never stop looking for new challenges and knowledge.

An EPA survey in 2018 asked members about desirable topics for future courses and identified Motivational Interviewing (MI) as the second most popular option, with 11% of 693 respondents choosing it. Consequently the EPA Committee on Education chose MI as the topic of their second online video course, following the successful 'Introduction to CBT' online course produced in 2018. The new course, titled 'Introduction to Motivational Interviewing', was made under the leadership of NHS consultant psychiatrist Dr Guy Undrill who is a member of the MI Network of Trainers. The videos also feature three of his current psychiatry trainees and an actor, which allowed the teaching style to reflect MI principles and made it possible to include roleplay scenarios that brought the topic to life. The course was filmed in January 2019 and the final version was released in June 2019 accompanied by a discussion forum in which the makers of the course answered questions about MI and how to use it in psychiatry. In this workshop we will explain what MI is, why it is suitable for an online course, and how the course was produced. We will also reflect on the initial feedback regarding the effectiveness of the course and think about the next steps for improving psychotherapy training for European psychiatrists.

The significant majority of patients with schizophrenia benefit from long term (maintenance) antipsychotic treatment (1), however the doses used in the practice are often higher, than recommended based on PET (2) and clinical studies (3). The two major sources of overdosing antipsychotics in patients with schizophrenia have been: 1. Lack of high quality studies about dose-efficacy relationship for antipsychotics in schizophrenia until the 1990s or even until recently. Studies with improved design, including plasma level and SPECT/PET as well as meta-analytic studies helped in understanding the relationship between dose of antipsychotics and clinical effects. 2. The frequent use of antipsychotic polypharmacy in schizophrenia (4). Polypharmacy has been widely practiced, often leading to high cumulative doses of antipsychotics, however the rigid rejection of antipsychotic polypharmacy by guidelines prevented the support of appropriate research in this field. Based on current evidence the following recommendations can be proposed: 1. Better training in psychopharmacology, including dosing of antipsychotics. 2. Supporting adequate research in antipsychotic polypharmacy in schizophrenia. References 1. Herold, R., Szekeres, G., & Bitter, I. (2017). Continuous maintenance antipsychotic treatment in schizophrenia. Psychiatria Hungarica, 32(3), 296-306. 2. Tauscher, J., Kapur, S. (2001). Choosing the right dose of antipsychotics in schizophrenia. CNS Drugs, 15(9), 671-678. 3. Leucht, S., et al. Dose-Response Meta-Analysis of Antipsychotic Drugs for Acute Schizophrenia. American Journal of Psychiatry 2019 Dec 16:appiajp201919010034. doi: 10.1176/appi.ajp.2019.19010034. [Epub ahead of print] 4. Tiihonen, J. et al. (2019). Antipsychotic Polypharmacy vs Monotherapy With Psychiatric Rehospitalization Among Adults With Schizophrenia. JAMA Psychiatry, 76(5), 499-507.

Depression is one of the most common mental health problems in the elderly and is associated with a significant burden of illness affecting patients, their families and communities. Selecting, adjusting, and changing antidepressants in the elderly in a sequential way has shown response and remission rates similar to those of younger adults. However, antidepressants may be less effective in older patients because they have a greater burden of somatic disorders (including white matter lesions) and because their physicians have a tendency to prescribe suboptimal doses. Physicians are also increasingly prescribing antidepressants in elderly patients for non-depressive indications (including off-label) such as anxiety disorders, insomnia, pain, panic disorders (with or without agoraphobia), fibromyalgia, obsessive-compulsive disorder, social phobia, nicotine dependence, attention deficit hyperactivity disorder, posttraumatic stress disorder, digestive system disorders, urinary system disorders, bulimia nervosa, … This workshop will give an overview of the literature and will include clinical advise based on current guidelines.

Pharmacokinetic and pharmacodynamic considerations of antipsychotic and antidepressant treatment is one of the key aspects of medication dosing. These medications are very different in terms of pharmacokinetic and pharmacodynamic profiles that can affect dosing and therefore this knowledge is necessary to manage these problems in real clinical practice. In addition, many trials and meta-analyses including older adults have been conducted without these very important considerations; however patients with these problems are the most frequent in real clinical practice and are frequently treated with multiple medications (polypharmacy) and have high comorbidities and drug-drug interactions. Most problems could be avoided by adopting appropriate treatment strategies (e.g. tools) including pharmacokinetic tools, collaborative care, and different medication lists.

In this workshop we will present firstly a pharmacokinetic and a pharmacodynamic overview of medication dosing and possible tools to reduce problems in these areas. The main focus of this talk will be on treatment hints which could be used in real clinical practice to reduce these problems and their clinical consequences in older adults.

In February 2017, Russia decriminalized domestic violence in cases where it does not cause “substantial bodily harm” and does not happen more than once a year. The independent media outlets have published a joint study on violence against women in Russia. Nearly four in five women convicted of murder in Russia have survived domestic violence. According to Russian police statistics, 15.381 women suffered domestic violence in the first nine months of 2019. This paper explores the common concerns expressed by experts, gives an overview of some cases (Khachaturian sisters’ case – three teenage sisters stabbed and battered their father to death, the girls’ father abused them physically and psychologically for years; the case of Margarita Gracheva – the 27-year-old mother of two boys, the husband chopped off her hands; and Ms. Yeshchenko case – the lover and former student of a historian who murdering her and dismembering her body) and provides strategies for prevention. This paper uses these endeavors as a case study with which to explore the perceived responsibilities of psychiatrists, to comment on and respond to the broader social and political context. This paper is a multi-stakeholder exploration of the position of my own with regard to the way preventive issues were being handled within the context of changing practices, policy, legislation and attitudes. The lessons learned to date the tricks and the pitfalls will be discussed.

Renaming schizophrenia which started from Japan has received heterogeneous reactions from all over the world. Some countries, associations and experts consider it as an opportunity to fight against stigma while others do not share this perspective. Reactions, initiatives and proposals collected from EPA (European Psychiatric Association) member National Psychiatric Associations (NPAs) will be summarized to facilitate the discussion. A survey, consisting of structured and semi-structured questions was sent to 44 EPA member NPAs from 40 countries. Main purpose of the survey was to search and collect the NPAs’ opinions on several perspectives including any previous or planned action for this issue, possible prediction on whether renaming could be effective on stigmatization in their countries and cultures, and any proposals as possible new names for schizophrenia. Also, NPAs had been requested to provide evaluations of their Psychosis or Schizophrenia Section members, or other experts from their countries via the same instrument. The collected data will be presented in this workshop to facilitate the discussion and to elaborate Europe-wide or country specific positions and needs on the issue.

Many patients, clinicians, and researchers consider the label schizophrenia to be stigmatizing. Thus, over the last years, a name change has increasingly been discussed to relieve patients from the negative beliefs, prejudice, and discrimination associated with the label schizophrenia (Gaebel & Kerst, 2019). In different world regions, stakeholders have developed alternative labels for schizophrenia. For example, some Asian countries have implemented alternative names in their respective healthcare systems. Also in Europe, different alternative labels have been proposed (e.g., salience dysregulation syndrome), but none have, thus far, been systematically implemented in mental healthcare. In sum, to date, there is no commonly agreed upon alternative label or conceptualization to replace schizophrenia internationally. Meeting relevant criteria for a new name, finding agreement among all involved stakeholders and replacing the established term is a complex process. This effort would be worthwhile if it contributes to a reduction of stigmatization and an improvement in mental healthcare for patients with schizophrenia. Thus far, however, there is only limited empirical evidence that a name change alone will achieve the desired effects. Hence, it may be premature to abandon the concept of schizophrenia, which has proven its reliability, clinical utility, and validity over the last century. In this lecture, the challenges, potential risks, and potential advantages of developing an internationally consistent alternative label for schizophrenia will be discussed. Gaebel, W., & Kerst, A. (2019). The debate about renaming schizophrenia: a new name would not resolve the stigma. Epidemiology and Psychiatric Sciences, 28(3), 258-261.

Current early-career psychiatrists (ECPs) were grown and trained in the internet era, and web-based tools have expanded their international research possibilities. As real-time communication across the world has been enabled, ECPs can start and expand multicentric research studies with transcultural and multidisciplinary perspectives of many colleagues from developed and developing countries. This research could be much better in sample sizes and impact than small studies in single locations; furthermore, many ECPs may find it easier to join and lead web-based research teams that in their local institutions. However, these large and heterogeneous teams face unique challenges when aiming at coordinating effectively their efforts and translating them into high-impact scientific publications. This talk will discuss these opportunities and challenges, with a practical viewpoint, offering examples of accessible internet-based tools and successful and ongoing research studies. The speaker has participated in and leaded studies of this such and aims to enhance a discussion among listeners on how to further promote and improve this kind of research.

A systematic review is a research article that identifies a specific review question, identifies all relevant studies, appraises their quality, and summarizes the results of all high-quality research evidence using a scientific methodology. High-quality research includes those studies with an explicit and rigorous design and those that answer a given research question. Understanding of systematic reviews and implementing them in practice is becoming essential for all healthcare professionals. However, before using the results, it is crucial to appraise a systematic review accurately by asking a series of questions to evaluate whether the review conducted all the steps correctly with minimal bias. Several steps, when conducting a systematic review, will be covered in this presentation. 1. Asking an answerable and focused review question 2. Writing the plan and background to the review 3. Specifying objectives and inclusion and exclusion criteria 4. Conducting a comprehensive and systematic literature search 5. Working with primary papers: selecting, appraising and extracting data 6. Synthesizing, summarizing and presenting findings 7. Writing up discussion and completion review 8. Sharing, disseminating, and using systematic reviews to inform and improve practice.

Several environmental exposures have been associated with mental disorders: childhood adversities, stressful life events, drug and alcohol use, obstetric and pregnancy complications, urban environment, and ethnic minority status. Research has thus far investigated the association between a single psychiatric outcome and a single environmental exposure, such as childhood adversities and psychosis. However, exposures come in dense networks of closely related and interactive elements. The exposome, the totality of the environmental exposures (nongenetic component) from the prenatal period onwards, consists of dynamic, interactive, and intertwined categories that include the internal (e.g., gut microflora), the specific external (e.g., drug use), and the general external (e.g., urban environment). The exposome approach offers a holistic understanding of environment, similar to the genome concept, and provides a theoretical framework to investigate the role of the poly-gene and poly-environment in mental health. Guided by the exposome paradigm, we showed how predictive modeling approaches could be applied to construct an exposome score (ES) for schizophrenia, which is a single metric of aggregated environmental load, similar to polygenic risk score. In a series of research, we further demonstrated the utility of the ES for schizophrenia for estimating environmental load, testing gene-environment interactions, and stratification in independent datasets. Galvanized by the availability of growing amounts of multimodal, multilevel, multidimensional data, along with the accessible advanced statistical learning methods to handle high-dimensional data, exposome research is anticipated to the catch up with the pace of progress in the psychiatric genomics.

The ability to determine the direction of one’s work, is one of the important goals in my working life. To achieve it, a mentorship and role models of female teachers and scientists in all stages of my education alongside with many other male role models were important for my personal and career development. Also, to learn how very negative life events and key obstacles can be overcome when being aware of the long-time perspective and the context one lives in.

The relationship between aggressiveness and violence (A/V) in psychiatric disorders is an enduring topic where strong opinions tend to stem far beyond scientific evidence. Unluckily, mass media often tend to emphasize mental illness as the leading cause of violence in mass-shootings or terrorist attacks, and cinematographic depictions of the mentally ill are often unrealistically sensationalized, contributing to stigma concerning psychiatric conditions. Bipolar disorder (BD) is is a chronic recurring condition characterized, among other aspects, by wide variations in mood and energy levels. The clinically frequent co-occurrence of increased impulsivity with mood and energy activation leads to an unmediated, automated cliché of increased rates of aggressiveness or violence (A-V). This presentation will focus on the clinical correlates of A/V in BD as a paradigm and pitfall of current research concerning A/V in psychiatric disorders. Aspects discussed will outline the possible factors, or lack of, predisposing to A/V in clinical settings. Implications of the possible presence of A/V on patients’ course of illness, functioning and quality of life will be discussed, as well as possible multidisciplinary approaches that may alleviate the impact of A/V on both patients and care-givers

Elderly people with intellectual disabilities represent one of the fastest growing groups of the special needs populations. This is mainly the consequence of improved and adaptive care standards as well as better general medical treatments. Living longer also carries more mental health problems, including those related to cognitive dysfunction and dementia. Such patients are often treated with antipsychotics and mood stabilizers, with main reason to use of these drugs being „sedation”. At least some of them may benefit form cholinesterase inhibitors and / or memantine, although evidence form clinical trials is scarce. Also antidepressants, particularly those blocking serotonin and / or norepinephrine transporters are probably underused. Importantly, understanding behavioral and psychological problem of these patients within the frame of the biopsychosocial paradigm might be useful, leading to potentially effective and harmless non-pharmacological interventions. Particularly, the concepts of attention to frustrated needs and reactions to environmental change may prove to be fruitful.

The care for persons with intellectual disability is usually an effort taken by their parents or other members of the family. The amount of time and devotion to this task depends highly on the level of the disability. At different phases of life of the person with intellectual disability the care is shared with different institutions like rehabilitation centers, special schools, vocational workshops, occupational activity centres etc. However, at the older age the health problems may increase, including the development of early dementia, which makes the participation in the above programs no longer possible. This causes that the responsibility of the caregivers increases, which requires still more efforts from them. This situation is complicated with the fact that the caregivers themselves grow older and they often need a support for themselves. Described here is a case of a female patient suffering from Down syndrome, who used to participate in a program of a vocational training workshop for many years, which allowed her for social integration and acquiring news skills. However, as she grew older, the signs of early dementia appeared, which were later accompanied with neurological symptoms, which made walking no longer possible for her. As she became unable to participate in the accessible rehabilitation programs anymore, she had to stay at home with her mother. The possible ways to support and assist her mother as a caregiver in this situation are discussed.

Background. Inpatient care for anorexia nervosa is used for patients at high medical and psychiatric risk and who cannot be safely managed as outpatients. Approximately a third of patients relapse within the first 6 months. The aim of this programme of work was to examine whether psychoeducational interventions preparing for the transition back to the community codesigned by, and for, carers and patients to carers are of benefit. Methods Study 1 (CASIS). Patients (n=178) admitted to inpatient units across the UK entered a randomised trial in which carers received treatment as usual, with, or without augmentation with carers self-management materials. Outcomes were followed over two years (Hibbs et al 2016, Magill et al 2017). Study 2 (TRIANGLE pilot) Patient (n=31) and carers (n=21) admitted to inpatient care were given the ECHOMANTRA intervention (with separate subsections for each) and were followed for 3 months after discharge (Adamson et al 2019). Results In CASIS, carer burden was reduced (Effect size 0.5) as was carer emotional behaviour (Effect size 0.5). The length of admission was shortened (148 vs 168 days) and re-admission rates were reduced (27% vs 32%; p=0.04). In the TRIANGLE pilot there were positive comments about the collaborative work from both parties. The length of admission was reduced by 4.5 weeks and weight gain was increased by 0.11 kg/week in the group given the ECHOMANTRA intervention in comparison to outcomes from audit data. Conclusion Augmenting treatment to help patients and carers to prepare for discharge can consolidate changes from inpatient care.