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Chloride channel 2 gene (Clc2) maps to chromosome 16 of the mouse, extending a region of conserved synteny with human chromosome 3q

Published online by Cambridge University Press:  14 April 2009

Andreas Lengeling ,
Monika Gronemeier ,
Melanie Ronsiek ,
Astrid Thiemann ,
Thomas J. Jentsch  and
Harald Jockusch
Andreas Lengeling
Affiliation:
Developmental Biology Unit, University of Bielefeld, D33501 Bielefeld, Federal Republic of Germany. Fax: +49 (521) 106 5654
Monika Gronemeier
Affiliation:
Developmental Biology Unit, University of Bielefeld, D33501 Bielefeld, Federal Republic of Germany. Fax: +49 (521) 106 5654
Melanie Ronsiek
Affiliation:
Developmental Biology Unit, University of Bielefeld, D33501 Bielefeld, Federal Republic of Germany. Fax: +49 (521) 106 5654
Astrid Thiemann
Affiliation:
Centre of Molecular Neurobiology, University of Hamburg, Martinistraase 52, D-20246 Hamburg, Federal Republic of Germany. Fax: +49(40)4717 4839
Thomas J. Jentsch
Affiliation:
Centre of Molecular Neurobiology, University of Hamburg, Martinistraase 52, D-20246 Hamburg, Federal Republic of Germany. Fax: +49(40)4717 4839
Harald Jockusch
Affiliation:
Developmental Biology Unit, University of Bielefeld, D33501 Bielefeld, Federal Republic of Germany. Fax: +49 (521) 106 5654
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Summary

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The Clc2 gene of the mouse codes for the ubiquitously expressed chloride channel ClC-2, a member of a family of at least seven voltage gated chloride channels, some of which are implicated in hereditary diseases. Using a mouse interspecies back-cross panel, we have mapped Clc2 to Chr 16, proximal to the somatostatin gene Smst, extending a region of documented conserved synteny to human Chr 3q.

Type
Short Paper
Information
Genetics Research , Volume 66 , Issue 2 , October 1995 , pp. 175 - 178
Copyright
Copyright © Cambridge University Press 1995

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