Hostname: page-component-78c5997874-ndw9j Total loading time: 0 Render date: 2024-11-08T08:36:16.960Z Has data issue: false hasContentIssue false
  • English
  • Français

‘Dappled’ a new allele at the Mottled locus in the house mouse

Published online by Cambridge University Press:  14 April 2009

Rita J. S. Phillips
Rita J. S. Phillips
Affiliation:
Medical Research Council Radiobiological Research Unit, Harwell, Berkshire, England
Rights & Permissions [Opens in a new window]

Extract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Dappled, a new completely sex-linked semi-dominant lethal mutation, is described. It is probably a new allele at the Mottled locus and has been given the symbol Modp.

Heterozygous adult females have a variegated coat very similar to that of Brindled and Mottled females; they have curly vibrissae at birth and some also have clubbed feet. All the characteristics are variable.

Hemizygous males die at about 17 days' gestation; they show a characteristic bending and thickening of the ribs and other skeletal defects. The cause of death is unknown.

Type
Research Article
Information
Genetics Research , Volume 2 , Issue 2 , July 1961 , pp. 290 - 295
Copyright
Copyright © Cambridge University Press 1961

References

REFERENCES

Carter, T. C., Lyon, M. F. & Phillips, R. J. S. (1958). Genetic hazard of ionizing radiations. Nature, Lond., 182, 409.Google Scholar
Dickie, M. M. (1954). The Tortoiseshell house mouse. J. Hered. 45, 158–159.Google Scholar
Falconer, D. S. (1953). Total sex linkage in the house mouse. Z. indukt. Abstamm.-u. VererbLehre, 85, 210–219.Google Scholar
Falconer, D. S. (1954). Linkage in the mouse: the sex-linked genes and ‘Rough’. Z. indukt. Abstamm.- u VererbLehre, 86, 263–268.Google ScholarPubMed
Fraser, A. S., Sobey, S. & Spicer, C. C. (1953). ‘Mottled’, a sex-modified lethal in the house mouse. J. Genet. 51, 217–221.CrossRefGoogle Scholar
Lyon, M. F. (1960). A further mutation of the Mottled type in the house mouse. J. Hered. 51, 116–121.CrossRefGoogle Scholar
Phillips, R. J. S. (1954). Jimpy, a new totally sex-linked gene in the house mouse. Z. indukt. Abstamm.- u. VererbLehre, 86, 322–326.Google Scholar
Welshons, W. J. & Russell, L. B. (1959). The Y-chromosome as the bearer of male determining factors in the mouse. Proc. not. Acad. Sci., Wash., 45, 560–566.CrossRefGoogle ScholarPubMed