Hostname: page-component-78c5997874-xbtfd Total loading time: 0 Render date: 2024-11-19T11:36:50.746Z Has data issue: false hasContentIssue false

Mutation induced in germ cells of the foetal female mouse

Published online by Cambridge University Press:  14 April 2009

T. C. Carter
Affiliation:
Medical Research Council's Radiobiological Research Unit, Harwell, Berkshire, England
Rights & Permissions [Opens in a new window]

Extract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

In Great Britain by far the greater part of the genetically effective dose of man-made radiation to the human population is due to high-intensity irradiation of the gonads in medical radiology; about a third of it is received by post-natal males, a third by post-natal females, and a third by foetuses, mainly in the later stages of gestation (Osborn & Smith, 1956).

Type
Research Article
Copyright
Copyright © Cambridge University Press 1960

References

REFERENCES

Carter, T. C. (1958). Radiation-induced gene mutation in adult female and foetal male mice. Brit. J. Radiol. 31, 407411.CrossRefGoogle ScholarPubMed
Carter, T. C., Lyon, M. F. & Phillips, R. J. S. (1956). Induction of mutation in mice by chronic gamma irradiation: interim report. Brit. J. Radiol. 29, 106108.CrossRefGoogle ScholarPubMed
Carter, T. C., Lyon, M. F. & Phillips, R. J. S. (1958). Genetic hazard of ionizing radiations. Nature, Land., 182, 409.CrossRefGoogle ScholarPubMed
Osborn, S. B. & Smith, E. E. (1956). The genetically significant radiation dose from the diagnostic use of X rays in England and Wales. Lancet, I, 949953.CrossRefGoogle Scholar
Russell, W. L. (1951). X-ray-induced mutations in mice. Cold Spr. Harb. Symp. quant. Biol. 16, 327336.CrossRefGoogle ScholarPubMed
Russell, W. L., Bangham, J. W. & Gower, J. S. (1958). Comparison between mutations induced in spermatogonial and postspermatogonial stages in the mouse. (Abstract.) Proc. Tenth Int. Congr. Genet. 2, 245–6.Google Scholar
Russell, W. L., Russell, L. B. & Cupp, M. B. (1959). Dependence of mutation frequency on radiation dose rate in female mice. Proc. Nat. Acad. Sci., Wash., 45, 1823.CrossRefGoogle ScholarPubMed
Russell, W. L., Russell, L. B., Gower, J. S. & Maddux, S. C. (1958). Radiation-induced mutation rates in female mice. Proc. Nat. Acad. Sci., Wash., 44, 901905.CrossRefGoogle ScholarPubMed
Russell, W. L., Russell, L. B. & Kelly, E. M. (1958). Radiation dose rate and mutation frequency. Science, 128, 15461550.CrossRefGoogle ScholarPubMed
Snell, G. D. (1941). Biology of the Laboratory Mouse. Philadelphia: Blakiston Company.Google Scholar