Hostname: page-component-586b7cd67f-vdxz6 Total loading time: 0 Render date: 2024-11-25T04:51:41.407Z Has data issue: false hasContentIssue false

The tabby locus (Ta) in the mouse: its site of action in tail and body skin

Published online by Cambridge University Press:  14 April 2009

Pamela R. Pennycuik
Affiliation:
CSIRO, Division of Animal Production, P.O. Box 239, Blacktown, N.S.W., 2148, Australia
Kathryn A. Raphael
Affiliation:
CSIRO, Division of Animal Production, P.O. Box 239, Blacktown, N.S.W., 2148, Australia
Rights & Permissions [Opens in a new window]

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

By means of grafting skin in which the epidermis of one genotype was combined with dermis of another to a nude host, we have shown that the effect of the mutant at the tabby (Ta) locus on follicle initiation in tail skin was not confined to either the epidermis or the dermis, that the effect of Ta on the morphology of body hairs was determined by the epidermis but that the close proximity of epidermis of a different genotype also affected body hair morphology.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1984

References

REFERENCES

Claxton, J. H. (1966). The hair follicle group in mice. Anatomical Record 154, 195208.CrossRefGoogle ScholarPubMed
Claxton, J. H. (1967). The initiation and development of the hair follicle population in tabby mice. Genetical Research 10, 161171.CrossRefGoogle Scholar
Dry, F. W. (1926). The coat of the mouse (Mus musculus). Journal of Genetics 16, 287340.CrossRefGoogle Scholar
Falconer, D. S. (1953). Total sex-linkage in the house mouse. Zeitschrift für Vererbungslehre 85, 210219.Google ScholarPubMed
Falconer, D. S., Fraser, A. S. & King, J. W. B. (1951). The genetics and development of ‘crinkled’, a new mutant in the house mouse. Journal of Genetics 50, 324344.CrossRefGoogle ScholarPubMed
Fraser, F. C. (1946). The expression and interaction of hereditary factors producing hypo-trichosus in the mouse: histology and experimental results. Canadian Journal of Research Section D Zoological Sciences 24, 1025.CrossRefGoogle ScholarPubMed
Grüneberg, H. (1969). Threshold phenomena versus cell heredity in the manifestation of sex-linked genes in mammals. Journal of Embryology and Experimental Morphology 22, 145179.Google ScholarPubMed
Grüneberg, H. (1971). The glandular aspects of the tabby syndrome in the mouse. Journal of Embryology and Experimental Morphology 25, 119.Google ScholarPubMed
Kindred, B. (1967). Some observations on the skin and hair of tabby mice. Journal of Heredity 58, 197199.CrossRefGoogle Scholar
Kollar, E. J. (1970). The induction of hair follicles by embryonic dermal papillae. Journal of Investigative Dermatology 55, 374378.CrossRefGoogle ScholarPubMed
Kollar, E. J. (1972). The development of the integument:spatial, temporal and phylogenetic factors. American Zoologist 12, 125135.CrossRefGoogle Scholar
McLaren, A., Gauld, I. K. & Bowman, P. (1973). Comparison between mice chimaeric and heterozygous for the X-linked gene tabby. Nature (London) 241, 180183.CrossRefGoogle ScholarPubMed
Mayer, T. C. & Green, M. C. (1978). Epidermis is the site of action of tabby (Ta) in the mouse. Genetics 90, 125131.CrossRefGoogle ScholarPubMed
Raphael, K. A. & Pennycuik, P. R. (1980). The site of action of the naked locus (N) in the mouse as determined by dermal-epidermal recombinations. Journal of Embryology and Experimental Morphology 57, 143153.Google ScholarPubMed
Rawles, M. E. (1963). Tissue interactions in scale and feather development as studies in dermal-epidermal recombinations. Journal of Embryology and Experimental Morphology 11, 765789.Google ScholarPubMed
Sofaer, J. A. (1974). Differences between tabby and downless mouse epidermis and dermis in culture. Genetical Research 23, 219225.CrossRefGoogle ScholarPubMed
Straile, W. E. (1965). Root sheath-dermal papilla relationships and the control of hair growth. In Biology of the Skin and Hair Growth, (ed. Lyne, A. G. and Short, B. F.), pp. 3557. Sydney: Angus and Robertson.Google Scholar