Hostname: page-component-586b7cd67f-g8jcs Total loading time: 0 Render date: 2024-11-28T05:12:44.815Z Has data issue: false hasContentIssue false
  • English
  • Français

Antimicrobial Stewardship Barriers and Goals in Pediatric Oncology and Bone Marrow Transplantation: A Survey of Antimicrobial Stewardship Practitioners

Published online by Cambridge University Press:  07 December 2015

Joshua Wolf ,
Yilun Sun ,
Li Tang ,
Jason G. Newland ,
Jeffrey S. Gerber ,
Christie J. Van Dyke ,
Saul R. Hymes ,
Diana Yu ,
Delia C. Carias  and
Penelope A. Bryant
Joshua Wolf*
Affiliation:
Department of Infectious Diseases, St. Jude Children’s Research Hospital, Memphis, Tennessee Department of Pediatrics, University of Tennessee Health Science Center, Memphis, Tennessee
Yilun Sun
Affiliation:
Department of Biostatistics, St. Jude Children’s Research Hospital, Memphis, Tennessee
Li Tang
Affiliation:
Department of Biostatistics, St. Jude Children’s Research Hospital, Memphis, Tennessee
Jason G. Newland
Affiliation:
Department of Pediatrics, Children’s Mercy Hospital, Kansas City, Missouri
Jeffrey S. Gerber
Affiliation:
Division of Infectious Diseases, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania
Christie J. Van Dyke
Affiliation:
Department of Pharmacy, Helen DeVos Children’s Hospital, Grand Rapids, Michigan
Saul R. Hymes
Affiliation:
Department of Pediatrics, Stony Brook Children’s Hospital, Stony Brook, New York
Diana Yu
Affiliation:
Department of Pharmacy, Children’s Mercy Hospital, Kansas City, Missouri
Delia C. Carias
Affiliation:
Pharmaceutical Department, St. Jude Children’s Research Hospital, Memphis, Tennessee
Penelope A. Bryant
Affiliation:
Infectious Diseases Unit, Department of General Medicine, Royal Children’s Hospital, Melbourne, Parkville, Victoria, Australia.
*
Address correspondence to Joshua Wolf, MBBS, FRACP, Department of Infectious Diseases, St. Jude Children’s Research Hospital, Mail Stop 320, 262 Danny Thomas Pl, Memphis, TN 38105 (joshua.wolf@stjude.org).
Get access Rights & Permissions [Opens in a new window]

Abstract

We undertook a cross-sectional survey of antimicrobial stewardship clinicians in North America and Australasia regarding practices, goals, and barriers to implementation of stewardship for pediatric oncology patients. Goals and barriers were similar regardless of clinician or institutional characteristics and geographic location. Strategies addressing these factors could help optimize antimicrobial use.

Infect. Control Hosp. Epidemiol. 2016;37(3):343–347

Type
Concise Communications
Information
Infection Control & Hospital Epidemiology , Volume 37 , Supplement 3 , March 2016 , pp. 343 - 347
Copyright
© 2015 by The Society for Healthcare Epidemiology of America. All rights reserved 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Footnotes

Members of the study group are listed at the end of the text.

Presented in part: 14th Annual St. Jude/Pediatric Infectious Diseases Society Pediatric Infectious Diseases Research Conference; Memphis, Tennessee; February 20, 2015; abstract R201538.

References

REFERENCES

1. Abbo, LM, Ariza-Heredia, EJ. Antimicrobial stewardship in immunocompromised hosts. Infect Dis Clin North Am 2014;28:263–279.CrossRefGoogle ScholarPubMed
2. Tverdek, FP, Rolston, KV, Chemaly, RF. Antimicrobial stewardship in patients with cancer. Pharmacotherapy 2012;32:722–734.Google Scholar
3. Sandora, TJ, Fung, M, Flaherty, K, et al. Epidemiology and risk factors for Clostridium difficile infection in children. Pediatr Infect Dis J 2011;30:580–584.Google Scholar
4. Sick, AC, Lehmann, CU, Tamma, PD, Lee, CK, Agwu, AL. Sustained savings from a longitudinal cost analysis of an Internet-based preapproval antimicrobial stewardship program. Infect Control Hosp Epidemiol 2013;34:573–580.CrossRefGoogle ScholarPubMed
5. Lehrnbecher, T, Phillips, R, Alexander, S, et al. Guideline for the management of fever and neutropenia in children with cancer and/or undergoing hematopoietic stem-cell transplantation. J Clin Oncol 2012;30:4427–4438.Google Scholar
6. Rosa, RG, Goldani, LZ, dos Santos, RP. Association between adherence to an antimicrobial stewardship program and mortality among hospitalised cancer patients with febrile neutropaenia: a prospective cohort study. BMC Infect Dis 2014;14:286.CrossRefGoogle Scholar
7. Newland, JG, Gerber, JS, Weissman, SJ, et al. Prevalence and characteristics of antimicrobial stewardship programs at freestanding children's hospitals in the United States. Infect Control Hosp Epidemiol 2014;35:265–271.Google Scholar
8. Society for Healthcare Epidemiology of America, Infectious Diseases Society of America, Pediatric Infectious Diseases Society. Policy statement on antimicrobial stewardship by the Society for Healthcare Epidemiology of America (SHEA), the Infectious Diseases Society of America (IDSA), and the Pediatric Infectious Diseases Society (PIDS). Infect Control Hosp Epidemiol 2012;33:322–327.CrossRefGoogle Scholar
9. Mihu, C, Paskovaty, A, Seo, S. Antimicrobial stewardship: considerations for a cancer center. In: Safdar A, ed. Principles and Practice of Cancer Infectious Diseases. New York: Humana Press, 2011:491–498.Google Scholar
10. Yeo, CL, Wu, JE, Chung, GW, Chan, DS, Fisher, D, Hsu, LY. Specialist trainees on rotation cannot replace dedicated consultant clinicians for antimicrobial stewardship of specialty disciplines. Antimicrob Resist Infect Control 2012;1:36.CrossRefGoogle ScholarPubMed
Supplementary material: PDF

Wolf supplementary material S1

Supplementary Figures

Download Wolf supplementary material S1(PDF)
PDF 180.6 KB
Supplementary material: PDF

Wolf supplementary material S2

Supplementary Figures

Download Wolf supplementary material S2(PDF)
PDF 314.8 KB