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Challenges in the Management of Infections due to Carbapenem-Resistant Enterobacteriaceae

Published online by Cambridge University Press:  10 May 2016

Dimitri M. Drekonja*
Affiliation:
Minneapolis Veterans Affairs Health Care System, Minneapolis, Minnesota Department of Medicine, University of Minnesota, Minneapolis, Minnesota
Susan E. Beekmann
Affiliation:
Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, Iowa
Sean Elliott
Affiliation:
Department of Pediatrics, University of Arizona, Tucson, Arizona
Deepa Mukundan
Affiliation:
Department of Pediatrics and Department of Medical Microbiology and Immunology, University of Toledo College of Medicine, Toledo, Ohio
Hari Polenakovik
Affiliation:
Department of Internal Medicine, Boonshoft School of Medicine, Wright State University, Dayton, Ohio
Marnie E. Rosenthal
Affiliation:
Department of Medicine, Section of Infectious Diseases, Jersey Shore University Medical Center, Neptune, New Jersey
Pranita D. Tamma
Affiliation:
Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland
Philip M. Polgreen
Affiliation:
Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, Iowa
Scott J. Weissman
Affiliation:
Center for Childhood Infections and Prematurity Research, Seattle Children's Research Institute, Seattle, Washington
*
Infectious Diseases (111F), Veterans Affairs Medical Center, 1 Veterans Drive, Minneapolis, MN 55417 (drek0002@umn.edu)

Abstract

Carbapenem-resistant Enterobacteriaceae (CRE) infections are increasing and are associated with considerable morbidity and mortality. Members of the Emerging Infections Network treating CRE encountered difficulties in obtaining laboratory results and struggled with limited treatment options. In addition, many treated patients experienced an alarming degree of drug toxicity from CRE therapies.

Type
Concise Communication
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2014

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