Hostname: page-component-7bb8b95d7b-w7rtg Total loading time: 0 Render date: 2024-09-11T14:11:39.516Z Has data issue: false hasContentIssue false
  • English
  • Français

Elevated Preoperative Fasting Serum Glucose Levels Increase the Risk of Postoperative Mediastinitis in Patients Undergoing Open Heart Surgery

Published online by Cambridge University Press:  02 January 2015

Stephen J. Wilson  and
Daniel J. Sexton
Stephen J. Wilson*
Affiliation:
Department of Medicine, Division of Infectious Diseases, Duke University School of Medicine, Durham, North Carolina
Daniel J. Sexton
Affiliation:
Department of Medicine, Division of Infectious Diseases, Duke University School of Medicine, Durham, North Carolina
*
Indiana University School of Medicine, Division of Infectious Diseases, 1001 West 10th Street, OPW430, Indianapolis, IN 46202
Get access Rights & Permissions [Opens in a new window]

Abstract

We conducted a case-control study to investigate the relationship between preoperative fasting serum glucose and postoperative mediastinitis in patients undergoing open heart surgery. Multivariate analysis revealed that a glucose level of 126 mg/dL or greater was associated with a significantly increased risk of mediastinitis (OR, 5.25; P = .002).

Type
Concise Communications
Information
Infection Control & Hospital Epidemiology , Volume 24 , Issue 10 , October 2003 , pp. 776 - 778
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2003

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.El Oakley, RM, Wright, JE. Postoperative mediastinitis: classification and management. Ann Thorax Surg 1996;61:1030–1036.CrossRefGoogle ScholarPubMed
2.Dellinger, EP. Preventing surgical-site infections: the importance of timing and glucose control. Infect Control Hosp Epidemiol 2001;22:604–606.CrossRefGoogle ScholarPubMed
3.Horan, TC, Gaynes, RP, Martone, WJ, Jarvis, WR, Emori, TG. CDC definitions of nosocomial surgical site infections, 1992: a modification of CDC definitions of surgical wound infections. Infect Control Hosp Epidemiol 1992;13:606–608.CrossRefGoogle ScholarPubMed
4.Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Diabetes Care 1997;20:1183–1197.CrossRefGoogle Scholar
5.Culver, DH, Horan, TC, Gaynes, RP, et al.Surgical wound infection rates by wound class, operative procedure, and patient risk index: National Nosocomial Infections Surveillance System. Am J Med 1991;91(suppl 3B):152S–157S.CrossRefGoogle ScholarPubMed
6.Zerr, KJ, Furnary, AP, Grunkemeier, GL, Bookin, S, Kanhere, V, Starr, A. Glucose control lowers the risk of wound infection in diabetics after open heart operations. Ann Thorac Surg 1997;63:356–361.CrossRefGoogle ScholarPubMed
7.Trick, WE, Scheckler, WE, Tokars, JI, et al.Modifiable risk factors associated with deep sternal site infection after coronary artery bypass grafting. J Thorac Cardiovasc Surg 2000;119:108–114.CrossRefGoogle ScholarPubMed
8.Latham, R, Lancaster, AD, Covington, JF, Pirolo, JS, Thomas, CS. The association of diabetes and glucose control with surgical-site infections among cardiothoracic surgery patients. Infect Control Hosp Epidemiol 2001;22:607–612.CrossRefGoogle ScholarPubMed
9.Rupp, ME. Mediastinitis. In: Mandeli, GL, Bennett, JE, Dolin, R, eds. Mandeli, Douglas, and Bennett's Principles and Practice of Infectious Diseases, 5th ed. Philadelphia: Churchill Livingstone; 2000:941–949.Google Scholar
10.McMahon, MM, Bistrian, BR. Host defenses and susceptibility to infection in patients with diabetes mellitus. Infect Dis Clin North Am 1995;9:1–9.CrossRefGoogle ScholarPubMed