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Isoniazid-Resistant Cavitary Tuberculosis in a Physician Following Isoniazid Prophylaxis

Published online by Cambridge University Press:  02 January 2015

Tobi B. Karchmer ,
John D. Phipps ,
Eve T. Giannetta  and
Barry M. Farr
Tobi B. Karchmer
Affiliation:
University of Virginia Health System, Charlottesville, Virginia
John D. Phipps
Affiliation:
University of Virginia Health System, Charlottesville, Virginia
Eve T. Giannetta
Affiliation:
University of Virginia Health System, Charlottesville, Virginia
Barry M. Farr*
Affiliation:
University of Virginia Health System, Charlottesville, Virginia
*
Box 473, University of Virginia Health System, Charlottesville, VA 22908
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Abstract

Single-drug prophylaxis is recommended after tuberculin skin test conversion, but not when there is active disease on chest radiograph because resistance develops frequently. Isoniazid-resistant tuberculosis developed in a physician receiving prophylaxis despite “faint left upper lobe soft tissue density” on chest radiograph. Ignoring active disease on chest x-ray renders this strategy counterproductive and cost ineffective. '(Infect Control Hosp Epidemiol 2002;23:622-625).

Type
Concise Communications
Information
Infection Control & Hospital Epidemiology , Volume 23 , Issue 10 , October 2002 , pp. 622 - 625
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2002

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