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Molecular Epidemiology of Staphylococcus aureus Colonization in 2 Long-Term Care Facilities

Published online by Cambridge University Press:  21 June 2016

Lona Mody ,
Erica Flannery ,
Andrew Bielaczyc  and
Suzanne F. Bradley
Lona Mody*
Affiliation:
Geriatric Research Education and Clinical Center, Veterans Affairs Ann Arbor Healthcare System and from the Division of Geriatric Medicine, University of Michigan, Ann Arbor
Erica Flannery
Affiliation:
Division of Infectious Diseases, Department of Internal Medicine, University of Michigan, Ann Arbor
Andrew Bielaczyc
Affiliation:
Division of Infectious Diseases, Department of Internal Medicine, University of Michigan, Ann Arbor
Suzanne F. Bradley
Affiliation:
Geriatric Research Education and Clinical Center, Veterans Affairs Ann Arbor Healthcare System and from the Division of Geriatric Medicine, University of Michigan, Ann Arbor Division of Infectious Diseases, Department of Internal Medicine, University of Michigan, Ann Arbor
*
Veterans Affairs Ann Arbor Healthcare System, 11 G, GRECC, 2215 Fuller Road, Ann Arbor, MI 48105 (lonamody@umich.edu)
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Abstract

Persistent colonization with Staphylococcus aureus was assessed in 22 nursing home residents. Eighteen residents (82%) remained colonized with the same strain found at baseline; 6 (33%) of 18 residents transiently acquired a new strain. Four residents (18%) acquired a new persistent strain. Residents colonized with methicillin-resistant S. aureus were more likely to acquire a new strain (67%) than were residents colonized with methicillin-susceptible S. aureus (20%) (P = .04).

Type
Concise Communications
Information
Infection Control & Hospital Epidemiology , Volume 27 , Issue 2 , February 2006 , pp. 212 - 214
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2006

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References

1.Bradley, SF. Staphylococcus aureus infections and antibiotic resistance in older adults. Clin Infect Dis 2002; 34:211–216.Google Scholar
2.Kluytmans, J, van Belkum, A, Verbrugh, H. Nasal carriage of Staphylococcus aureus: epidemiology, underlying mechanisms, and associated risks. Clin Microbiol Rev 1997; 10:505–520.CrossRefGoogle ScholarPubMed
3.Bradley, SF, Terpenning, MS, Ramsey, MA, et al. Methicillin-resistant Staphylococcus aureus: colonization and infection in a long-term facility. Ann Intern Med 1991; 115:417–422.Google Scholar
4.Nouwen, JL, Belkum, AV, Verbrugh, HA. Determinants of Staphylococcus aureus nasal carriage. Neth J Med 2001; 59:126–133.Google Scholar
5.Vandenbergh, MFQ, Yzerman, ED, Belkum, AV, et al. Follow-up of Staphylococcus aureus nasal carriage after 8 years: redefining the persistent carrier state. J Clin Microbiol 1999; 37:3133–3140.Google Scholar
6.Mody, L, Kauffman, CA, McNeil, SA, et al. Mupirocin-based decolonization of Staphylococcus aureus carriers in residents of 2 long-term care facilities: a randomized, double-blind, placebo-controlled trial. Clin Infect Dis 2003; 37:1467–1474.Google Scholar
7.Tenover, FC, Arbeit, R, Archer, G, et al. Comparison of traditional and molecular methods of typing isolates of Staphylococcus aureus. J Clin Microbiol 1994; 32:407–415.Google Scholar
8.Sanford, MD, Widmer, AF, Bale, MJ, et al. Efficient detection and long-term persistence of the carriage of methicillin-resistant Staphylococcus aureus. Clin Infect Dis 1994; 19:1123–1128.CrossRefGoogle ScholarPubMed
9.Scanvic, A, Denic, L, Gaillon, S, et al. Duration of colonization by methicillin-resistant Staphylococcus aureus after hospital discharge and risk factors for prolonged carriage. Clin Infect Dis 2001; 32:1393–1398.CrossRefGoogle ScholarPubMed
10.Drinka, PJ, Stemper, ME, Gauerke, CD, et al. Clustering of multiple endemic strains of methicillin-resistant Staphylococcus aureus in a nursing home: an 8-year study. Infect Control Hosp Epidemiol 2005; 26:215–218.Google Scholar
11.Muder, RR, Brennan, C, Wagener, MM, et al. Methicillin-resistant staphylococcal colonization and infection in a long-term care facility. Ann Intern Med 1991; 114:107–112.CrossRefGoogle ScholarPubMed
12.Nouwen, JL, Ott, A, Kluytmans-Vandenbergh, MFQ, et al. Predicting the Staphylococcus aureus nasal carriage state: derivation and validation of a “culture rule”. Clin Infect Dis 2004; 39:806–811.CrossRefGoogle ScholarPubMed
13.Trick, WE, Weinstein, RA, DeMarais, PL, et al. Colonization of skilled-care facility residents with antimicrobial-resistant pathogens. J Am Geriatr Soc 2001; 49:270–276.Google Scholar