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Detection of qacA/B in Clinical Isolates of Methicillin-Resistant Staphylococcus aureus from a Regional Healthcare Network in the Eastern United States

Published online by Cambridge University Press:  02 January 2015

Patrick McGann ,
Yoon I. Kwak ,
Amy Summers ,
James F. Cummings ,
Paige E. Waterman  and
Emil P. Lesho
Patrick McGann*
Affiliation:
Multidrug-Resistant Organism Repository and Surveillance Network, Walter Reed Army Institute of Research, Silver Spring, Maryland
Yoon I. Kwak
Affiliation:
Multidrug-Resistant Organism Repository and Surveillance Network, Walter Reed Army Institute of Research, Silver Spring, Maryland
Amy Summers
Affiliation:
Multidrug-Resistant Organism Repository and Surveillance Network, Walter Reed Army Institute of Research, Silver Spring, Maryland
James F. Cummings
Affiliation:
Department of Regulated Activities, Walter Reed Army Institute of Research, Silver Spring, Maryland
Paige E. Waterman
Affiliation:
Multidrug-Resistant Organism Repository and Surveillance Network, Walter Reed Army Institute of Research, Silver Spring, Maryland
Emil P. Lesho
Affiliation:
Multidrug-Resistant Organism Repository and Surveillance Network, Walter Reed Army Institute of Research, Silver Spring, Maryland
*
Walter Reed Army Institute of Research, 503 Robert Grant Avenue, 1E06, Silver Spring, MD 20910 (patrick.t.mcgann.ctr@us.army.mil)
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Abstract

We describe the clinical, microbiologic, and molecular features of the first series of qacA/B-containing strains of methicillin-resistant Staphylococcus aureus from infected US patients. All qac-carrying strains were clonally diverse, and qacA strains exhibited increased tolerance to chlorhexidine as measured by minimum inhibitory concentrations, minimum bactericidal concentrations, and postexposure colony counts.

Type
Concise Communications
Information
Infection Control & Hospital Epidemiology , Volume 32 , Issue 11 , November 2011 , pp. 1116 - 1119
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2011

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