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Emergence of Vancomycin-Resistant Enterococci in San Francisco Bay Area Hospitals During 1994 to 1998

Published online by Cambridge University Press:  02 January 2015

Jon Rosenberg ,
William R. Jarvis ,
Sharon L. Abbott ,
Due J. Vugia  and
California Emerging Infections Program
Jon Rosenberg*
Affiliation:
Infectious Diseases Branch, Berkeley, California
William R. Jarvis
Affiliation:
Division of Healthcare Quality Promotion, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia
Sharon L. Abbott
Affiliation:
Microbial Diseases Laboratory, Division of Communicable Disease Control, California Department of Health Services, Berkeley, California
Due J. Vugia
Affiliation:
Infectious Diseases Branch, Berkeley, California
California Emerging Infections Program
Affiliation:
The California Emerging Infections Program also includes S. Benson Werner and J. Michael Janda, Division of Communicable Disease Control, California Department of Health Services; Arthur Reingold, School of Public Health, University of California, Berkeley, California; and Gretchen Rothrock, Nandeeni Mukerjee, Lisa Gelling, Susan Shallow, and Pamala Daily, Public Health Foundation Enterprises, Oakland, California
*
Infectious Diseases Branch, Division of Communicable Disease Control, California Department of Health Services, 2151 Berkeley Way, Berkeley, CA 94704
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Abstract

Objective:

To determine the magnitude of van-comycin-resistant enterococci (VRE) in three counties in the San Francisco Bay area.

Design:

Active laboratory-based surveillance for VRE from January 1995 through December 1996 and a laboratory-based and hospital-based questionnaire survey for 1993 to 1994 and 1997 to 1998.

Setting:

All 33 general acute care hospitals in three counties in the San Francisco Bay area.

Participants:

Laboratories and infection control professionals serving these hospitals, and staff of the California Emerging Infections Program.

Results:

The number of hospitals reporting 1 or more patient clinical VRE isolates was 1 (3%) in 1993, 7 (21%) in 1994, 31 (94%) in 1995, and 33 (100%) in 1996 to 1998. The number of patient isolates increased from 1 in 1993 to 24 in 1994, 176 in 1995,429 in 1996, 730 in 1997, and 864 in 1998. Most VRE isolates in 1995 and 1996 were from urine and were not associated with serious clinical disease. However, the number of isolates from blood increased from 9 (6% of total) in 1995 to 44 (12% of the total) in 1996, 90 (14%) in 1997, and 100 (13%) in 1998.

Conclusions:

Our data document the rapid emergence and increase of VRE in all hospitals in three counties in the San Francisco Bay area during 1994 to 1998. Infection control measures for VRE together with antibiotic utilization programs should be implemented to limit further spread.

Type
Original Articles
Information
Infection Control & Hospital Epidemiology , Volume 25 , Issue 5 , May 2004 , pp. 408 - 412
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2004

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References

1.Kaplan, AH, Gilligan, PH, Facklam, RR. Recovery of resistant enterococci during vancomycin prophylaxis. J Clin Microbiol 1988;26:1216–1218.CrossRefGoogle ScholarPubMed
2.Murray, BE. Vancomycin-resistant enterococcal infections. N Engl J Med 2000;342:710–721.CrossRefGoogle ScholarPubMed
3.Martone, WJ. Spread of vancomycin-resistant enterococci: why did it happen in the United States? Infect Control Hosp Epidemiol 1998;19:539–545.CrossRefGoogle ScholarPubMed
4.Morrison, MA, Edwards, JR, Horan, TC, Richards, C, Tokars, JI. Changes in the epidemiology of vancomycin-resistant enterococci (VRE) in U.S. intensive care units (ICUs): 1992-2002. Presented at the 14th Annual Meeting of the Society for Healthcare Epidemiology of America; April 17-20, 2004; Philadelphia, PA.Google Scholar
5.Nosocomial enterococci resistant to vancomycin: United States, 1989-93. MMWR 1993;42:597–599.Google Scholar
6.Tokars, JI, Paul, SM, Crane, GL, Cetron, MS, Finelli, L, Jarvis, WR. Secular trends in bloodstream infection caused by antimicrobial-resistant bacteria in New Jersey hospitals, 1991 to 1995. Am J Infect Control 1997;25:395–400.CrossRefGoogle ScholarPubMed
7.Shay, DK, Maloney, SA, Montecalvo, M, et al.Epidemiology and mortality risk of vancomycin-resistant enterococcal bloodstream infections. J Infect Dis 1995;172:993–1000.CrossRefGoogle ScholarPubMed
8.Morris, JG Jr, Shay, DK, Hebden, JN, et al.Enterococci resistant to multiple antimicrobial agents, including vancomycin: establishment of endemicity in a university medical center. Ann Intern Med 1995;123:250–259.CrossRefGoogle Scholar
9.Moreno, F, Grota, P, Crisp, C, et al.Clinical and molecular epidemiology of vancomycin-resistant Enterococcus faecium. during its emergence in a city in southern Texas. Clin Infect Dis 1995;21:1234–1237.CrossRefGoogle Scholar
10.Washko, R, Dow, A, Henning, KJ. A citywide survey of vancomycin-resistant Enterococcus: New York City, 1993. Clin Infect Dis 1996;22:136–139.CrossRefGoogle ScholarPubMed
11.Montecalvo, MA, Shay, DK, Patel, P, et al.Bloodstream infections with vancomycin-resistant enterococci. Arch Intern Med 1996;156:1458–1462.CrossRefGoogle ScholarPubMed
12.Kim, WJ, Weinstein, RA, Hayden, MK. The changing molecular epidemiology and establishment of endemicity of vancomycin resistance in enterococci at one hospital over a 6-year period. J Infect Dis 1999;179:163–171.CrossRefGoogle Scholar
13.Bischoff, WE, Reynolds, TM, Hall, GO, Wenzel, RP, Edmond, MB. Molecular epidemiology of vancomycin-resistant Enterococcus faecium in a large urban hospital over a 5-year period. J Clin Microbiol 1999;37:3912–3916.CrossRefGoogle Scholar
14.Institute of Medicine. Emerging Infections: Microbial Threats to Health in the United States. Washington, DC: National Academy Press; 1992:113–137.Google Scholar
15.Murray, BE. Can antibiotic resistance be controlled? N Engl J Med 1994;330:1229–1230.CrossRefGoogle ScholarPubMed
16.Lorian, V. The need for surveillance for antimicrobial resistance. Infect Control Hosp Epidemiol 1995;16:638–641.CrossRefGoogle ScholarPubMed
17.Centers for Disease Control and Prevention. Statewide surveillance for antibiotic-resistant bacteria: New Jersey, 1992-1994. MMWR 1995;44:504–506.Google Scholar
18.Dembek, ZF, Kellerman, SE, Ganley, L, et al.Reporting of vancomycin-resistant enterococci in Connecticut: implementation and validation of a state-based surveillance system. Infect Control Hosp Epidemiol 1999;20:671–675.CrossRefGoogle ScholarPubMed
19.Tenover, FC, Tokars, J, Swenson, JM, Paul, S, Spiltany, K, Jarvis, W. Ability of clinical laboratories to detect antimicrobial agent-resistant enterococci. J Clin Microbiol 1993;31:1695–1699.CrossRefGoogle ScholarPubMed
20.Tenover, FC, Swenson, JM, O'Hara, CM, Stocker, SA. Ability of commercial and reference antimicrobial susceptibility testing methods to detect vancomycin resistance in enterococci. J Clin Microbiol 1995;33:1524–1527.CrossRefGoogle ScholarPubMed
21.Rosenberg, J, Tenover, FC, Wong, J, Jarvis, J, Vugia, D. Are clinical laboratories in California accurately reporting vancomycin-resistant enterococci? J Clin Microbiol 1997;35:2526–2530.CrossRefGoogle ScholarPubMed
22.Facklam, RR, Collins, MD. Identification of Enterococcus species isolated from human infections by a conventional test scheme. J Clin Microbiol 1989;27:731–734.CrossRefGoogle ScholarPubMed
23.Matushek, MG, Bonten, MJ, Hayden, MK. Rapid preparation of bacterial DNA for pulsed-field gel electrophoresis. J Clin Microbiol 1996;34:2598–2600.CrossRefGoogle ScholarPubMed
24.Tenover, FC, Arbeit, RD, Goering, RV, et al.Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J Clin Microbiol 1995;33:2233–2239.CrossRefGoogle ScholarPubMed
25.Ostrowsky, BE, Venkataraman, L, D'Agata, EM, Gold, HS, DeGirolami, PC, Samore, MH. Vancomycin-resistant enterococci in intensive care units: high frequency of stool carriage during a non-outbreak period. Arch Intern Med 1999;159:1467–1472.CrossRefGoogle ScholarPubMed
26.Ray, AJ, Hoyen, CK, Das, SM, Eckstein, EC, Donskey, CJ. Undetected vancomycin-resistant Enterococcus stool colonization in a Veterans Affairs hospital using a Clostridium difficile-focused surveillance strategy. Infect Control Hosp Epidemiol 2002;23:474–477.CrossRefGoogle Scholar
27.Landman, D, Volkert, F, Manikal, V, et al.Vancomycin-resistant enterococci in Brooklyn, New York: a moment in time. Clin Infect Dis 1999;29:1587–1588.CrossRefGoogle ScholarPubMed
28.Hospital Infection Control Practices Advisory Committee. Recommendations for preventing the spread of vancomycin-resistant enterococci. Infect Control Hosp Epidemiol 1995;16:105–113.CrossRefGoogle Scholar
29.Montecalvo, MA, Jarvis, WR, Uman, J, et al.Infection-control measures reduce transmission of vancomycin-resistant enterococci in an endemic setting. Ann Intern Med 1999;131:269–272.CrossRefGoogle Scholar
30.Ostrowsky, BE, Trick, WE, Sohn, AH, et al.Control of vancomycin-resistant enterococcus in health care facilities in a region. N Engl J Med 2001;344:1427–1433.CrossRefGoogle ScholarPubMed
31.Byers, KE, Anglim, AM, Anneski, CJ, et al.A hospital epidemic of vancomycin-resistant Enterococcus: risk factors and control. Infect Control Hosp Epidemiol 2001;22:140–147.CrossRefGoogle ScholarPubMed
32.Mayhall, CG. Control of vancomycin-resistant enterococci: it is important, it is possible, and it is cost-effective. Infect Control Hosp Epidemiol 2002;23:420–423.CrossRefGoogle ScholarPubMed
33.Srinivasan, A, Song, X, Ross, T, Merz, W, Brower, R, Perl, TM. A prospective study to determine whether cover gowns in addition to gloves decrease nosocomial transmission of vancomycin-resistant enterococci in an intensive care unit. Infect Control Hosp Epidemiol 2002;23:424–428.CrossRefGoogle Scholar
34.Goetz, AM, Rihs, JD, Wagener, MM, Muder, RR. Infection and colonization with vancomycin-resistant Enterococcus faecium in an acute care Veterans Affairs Medical Center: a 2-year survey. Am J Infect Control 1998;26:558–562.CrossRefGoogle Scholar
35.Slaughter, S, Hayden, MK, Nathan, C, et al.A comparison of the effect of universal use of gloves and gown with that of glove use alone on acquisition of vancomycin-resistant enterococci in a medical intensive care unit. Ann Intern Med 1996;125:448–456.CrossRefGoogle Scholar
36.Wells, CL, Juni, BA, Cameron, SB, et al.Stool carriage, clinical isolation, and mortality during an outbreak of vancomycin-resistant enterococci in hospitalized medical and/or surgical patients. Clin Infect Dis 1995;21:45–50.CrossRefGoogle ScholarPubMed
37.Boyce, JM. Vancomycin-resistant enterococcus: detection, epidemiology, and control measures. Infect Dis Clin North Am 1997;11:367–385.CrossRefGoogle ScholarPubMed
38.Boyce, JM. Consequences of inaction: importance of infection control practices. Clin Infect Dis 2001;33(suppl 3):S133–S137.CrossRefGoogle ScholarPubMed
39.Jochimsen, EM, Fish, L, Manning, K, et al.Control of vancomycin-resistant enterococci at a community hospital: efficacy of patient and staff cohorting. Infect Control Hosp Epidemiol 1999;20:106–109.CrossRefGoogle Scholar
40.Farr, BM, Jarvis, WR. Would active surveillance cultures help control healthcare-related methicillin-resistant Staphylococcus aureus infections? Infect Control Hosp Epidemiol 2002;23:65–68.CrossRefGoogle ScholarPubMed
41.Arnold, MS, Dempsey, JM, Fishman, M, McAuley, PJ, Tibert, C, Vallande, NC. The best hospital practices for controlling methicillin-resistant Staphylococcus aureus: on the cutting edge. Infect Control Hosp Epidemiol 2002;23:69–76.CrossRefGoogle ScholarPubMed
42.Muto, CA, Giannetta, ET, Durbin, LJ, Simonton, BM, Farr, BM. Cost-effectiveness of perirectal surveillance cultures for controlling vancomycin-resistant Enterococcus. Infect Control Hosp Epidemiol 2002;23:429–435.CrossRefGoogle ScholarPubMed
43.Muto, CA, Jernigan, JA, Ostrowsky, BE, et al.SHEA guideline for preventing nosocomial transmission of multidrug-resistant strains of Staphylococcus aureus and Enterococcus. Infect Control Hosp Epidemiol 2003;24:362–386.CrossRefGoogle ScholarPubMed
44.Boyce, JM, Pittet, D, Healthcare Infection Control Practices Advisory Committee, HICPAC/SHEA/APIC/IDSA Hand Hygiene Task Force. Guideline for hand hygiene in health-care settings. MMWR 2002;51(RR-16):1–44.Google ScholarPubMed
45.Wenzel, RP, Wong, MT. Managing antibiotic use: impact of infection control. Clin Infect Dis 1999;28:1126–1127.CrossRefGoogle ScholarPubMed
46.Fridkin, SK, Edwards, JR, Pichette, SC, et al.Determinants of vancomycin use in adult intensive care units in 41 United States hospitals. Clin Infect Dis 1999;28:1119–1125.CrossRefGoogle ScholarPubMed
47.Quale, J, Landman, D, Saurina, G, Atwood, E, DiTore, V, Patel, K. Manipulation of a hospital formulary to control an outbreak of vancomycin-resistant enterococci. Clin Infect Dis 1996;23:1020–1025.CrossRefGoogle ScholarPubMed
48.Schentag, JJ, Hyatt, JM, Carr, JR, et al.Genesis of methicillin-resistant Staphylococcus aureus (MRSA), how treatment of MRSA infections has selected for vancomycin-resistant Enterococcus faecium, and the importance of antibiotic management and infection control. Clin Infect Dis 1998;26:1204–1214.CrossRefGoogle ScholarPubMed
49.Jarvis, WR. Epidemiology, appropriateness, and cost of vancomycin use. Clin Infect Dis 1998;26:1200–1203.CrossRefGoogle ScholarPubMed
50.Cahill, CK, Rosenberg, J. Guideline for prevention and control of antibiotic resistant microorganisms in California long-term care facilities. Journal of Gerontological Nursing 1996;22:40–47.CrossRefGoogle ScholarPubMed
51.Trick, WE, Kuehnert, MJ, Quirk, SB, et al.Regional dissemination of vancomycin-resistant enterococci resulting from interfacility transfer of colonized patients. J Infect Dis 1999;180:391–396.CrossRefGoogle ScholarPubMed