Hostname: page-component-586b7cd67f-tf8b9 Total loading time: 0 Render date: 2024-11-27T02:55:12.174Z Has data issue: false hasContentIssue false

Psychosis? Beware - case series of clarithromycin and psychosis

Published online by Cambridge University Press:  13 June 2014

Adam Abba-Aji
Affiliation:
Psychiatry for Older People
Owen Mulligan
Affiliation:
Sligo Mental Health Services, Ballytivnan, Sligo, Ireland

Abstract

We describe two case reports presenting approximately one year apart These indicate a possible association between clarithromycin and psychosis. Such an association presents new challenges for clinicians based in non-psychiatric hospital settings and primary care physicians.

Type
Case report
Copyright
Copyright © Cambridge University Press 2007

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Rovold, KA. Clinical pharmacokinetics of clarithromycin. Clin Phamacokinet 1999; 37(5): 385395.CrossRefGoogle Scholar
2.Schmidt, Tet al.Clarithromycin lacks bactericidal activity in cerebrospinal fluid in experimental meningitis. J Antimicrob Chemother 1993; 32: 627632.CrossRefGoogle Scholar
3.Gomez-Gil, Eet al.Clarithromycin-induced acute psychoses in peptic ulcer disease; Eur J Clin Microbiol Infect Dis 1999; 18: 7071.Google ScholarPubMed
4.Elahi, F, Bhamjee, M. A case of clarithromycin psychoses. Psychiatric Bull 2004: 28; 9899.CrossRefGoogle Scholar
5.Kuriya, SIet al.Effects of clarithromycin and its metabolites on mixed function oxidase system hepatic microsomes of rats. Drug Metab Disp 1993; 21: 358363.Google Scholar
6.Yasui, Net al.Carbamazepine toxicity induced by clarithromycin co administration in psychiatric patients. Int Clin Psychopharmacol 1997; 12(4): 225229.CrossRefGoogle Scholar
7.Ahmed, A, Williams, RH. Clarithromycin-induced mania. Am J Psychiatry; 1998; 155(11): 1626.Google Scholar