Hostname: page-component-cd9895bd7-jkksz Total loading time: 0 Render date: 2024-12-20T17:26:22.991Z Has data issue: false hasContentIssue false
  • English
  • Français

The efficacy of the probiotic feed additive Calsporin® (Bacillus subtilis C-3102) in broilers: combined analysis of four different studies

Published online by Cambridge University Press:  20 March 2013

T. Marubashi ,
M. I. Gracia ,
E. Esteve-Garcia  and
M. Piskoríková
T. Marubashi*
Affiliation:
Calpis Co Ltd, 150-0022 Tokyo, Japan
M. I. Gracia
Affiliation:
Imasde Agroalimentaria S.L., 28224 Pozuelo de Alarcón, Spain
E. Esteve-Garcia
Affiliation:
IRTA Mas Bové, 43280 Reus, Spain
M. Piskoríková
Affiliation:
Pen & Tec Consulting SL, 08195 Sant Cugat del Vallès, Spain
*
*Corresponding author:feeddivision@calpis.co.jp
Get access Rights & Permissions [Opens in a new window]

Summary

The efficacy of the probiotic feed additive, Calsporin® (CAL; Bacillus subtilis C-3102), included in broiler diets at 50 mg/kg was evaluated using statistical meta-analysis of data from four different studies conducted using broilers from day-old to market weight at 42 days of age. The body weight, average daily gain, feed intake, feed to gain ratio, mortality and European Production Efficiency Factor (EPEF) data from each experiment were tested for homogeneity between trials before being pooled and analysed in combination to determine whether benefits were consistent independent of trial site and conditions. CAL supplementation significantly improved weight gain (P = 0.0037) between 1 and 21 days of age (3.3%) and feed conversion ratio (P = 0.0492) between 22 and 42 days of age (3.0%). Over the entire experimental period (day 1 to day 42 of age), broilers fed the CAL diets had significantly better (P = 0.0142) feed conversion (2.6%) and higher (P = 0.0062) EPEF (4.6%) compared to the controls. Birds fed diets supplemented with CAL were 1.6% heavier than controls at 42 days of age, a near-significant trend (P = 0.0558). The results demonstrated that CAL in broiler diets, added at an inclusion rate of 50 mg/kg, can be beneficial in terms of broiler performance.

Keywords

probioticCalsporin®broilerperformance
Type
Original Research
Information
Journal of Applied Animal Nutrition , Volume 1 , 2012 , e5
Copyright
Copyright © Cambridge University Press and Journal of Applied Animal Nutrition Ltd. 2013 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Agricultural Research Council of the National Academies. (1975) Nutrient Requirements of Farm Livestock, Poultry. 2nd Edn. The National Academies Press, London, United Kingdom.Google Scholar
AOAC. (2000) Official Methods of Analysis. 17th Edn. Association of Official Analytical Chemists, Arlington, VA, USA.Google Scholar
Blair, E.C., Allen, H.M., Brooks, S.E., Firman, J.D., Robbins, D.H., Nishimura, K. and Ishimaru H. (2004) Effects of CAL on turkey performance, carcass yield and nitrogen reduction. International Journal of Poultry Science, 3(1): 75–79.Google Scholar
Fritts, C.A., Kersey, J.H., Motl, M.A., Kroger, E.C., Yan, F., Si, J., Jiang, Q., Campos, M.M., Waldroup, A.L. and Waldroup, P.W. (2000) Bacillus subtilis (C-3102) CAL improves live performance and microbiological status of broiler chickens. The Journal of Applied Poultry Research, 9: 149–155.CrossRefGoogle Scholar
Maruta, K., Miyazaki, H., Masuda, S., Takahashi, M., Marubashi, T., Tadano, Y. and Takahashi, H. (1996) Exclusion of intestinal pathogens by continuous feeding with Bacillus subtilis C-3102 and its influence on the intestinal microflora in broilers. Animal Science Technology (Jpn), 67(3): 273–280.Google Scholar
National Research Council of the National Academies. (1994) Nutrient Requirements of Poultry. 9th Edn. The National Academies Press, Washington DC, USA.Google Scholar
Regulation (EC) No 1831/2003 of the European Parliament and of the Council of 22 September 2003 on additives for use in animal nutrition, http://europa.eu.int/eur-lex.Google Scholar
SAS Institute. (1990) SAS® User's Guide: Statistics. SAS Institute, Cary, NC, USA.Google Scholar
Vilà, B., Esteve-Garcia, E. and Brufau, J. (2010) Probiotic micro-organisms: 100 years of innovation and efficacy; modes of action. World's Poultry Science Journal, 66: 369–380.CrossRefGoogle Scholar