Hostname: page-component-cd9895bd7-fscjk Total loading time: 0 Render date: 2024-12-21T00:53:28.981Z Has data issue: false hasContentIssue false
  • English
  • Français

Cestocidal activity of Acacia auriculiformis

Published online by Cambridge University Press:  05 June 2009

N.K. Ghosh ,
S.P. Sinha Babu ,
N.C. Sukul  and
A. Ito
N.K. Ghosh
Affiliation:
Department of Zoology, Visva-Bharati University, Santiniketan-731235, West Bengal, India
S.P. Sinha Babu
Affiliation:
Department of Zoology, Visva-Bharati University, Santiniketan-731235, West Bengal, India
N.C. Sukul
Affiliation:
Department of Zoology, Visva-Bharati University, Santiniketan-731235, West Bengal, India
A. Ito
Affiliation:
Department of Parasitology, Gifu University School of Medicine, Gifu City 500, Japan
Get access Rights & Permissions [Opens in a new window]

Abstract

The cestocidal activity of Acacia auriculiformis was evaluated using rats each harbouring a single adult worm of Hymenolepis diminuta. The ethanol extract (300 mg/kg/day) and the saponins (200 mg/kg/day) obtained from the funicles of A. auriculiformis, were administered orally to two groups each of 10 rats, respectively, on day 20 after oral inoculation with a single cysticercoid of H. diminuta. Adult worms were expelled within 5 days from rats treated with the ethanol extract and within 3 days from those treated with saponins. No appreciable side effects were observed in the treated rats.

Type
Research Note
Information
Journal of Helminthology , Volume 70 , Issue 2 , June 1996 , pp. 171 - 172
Copyright
Copyright © Cambridge University Press 1996

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Chatterjee, A. & Sukul, N.C. (1981) Nematicidal action of three wild plants. Nematologica 26, 500–502.Google Scholar
Chatterjee, R.K., Fatma, N., Murthy, P.K., Sinha, P., Kulshrestha, D.K. & Dhawan, B.N. (1992) Macro-filaricidal activity of the stembark of Streblus asper and its major active constituents. Drug Development Research 26, 1–12.CrossRefGoogle Scholar
Ghosh, M., Sinha, Babu S.P., Sukul, N.C. & Mahato, S.B. (1993) Antifilarial effect of two triterpenoid saponins isolated from Acacia auriculiformis. Indian Journal of Experimental Biology 31, 604–606.Google ScholarPubMed
Ghosh, M., Sinha, Babu S.P., Sukul, N.C., Sahu, N.P. & Mahato, S.B. (1994) Antifilarial effect of solamargine isolated from Solanum khasianum. International Journal of Pharmacognosy 32 (2), 184–190.CrossRefGoogle Scholar
Ito, A. & Onitake, K. (1987) Hymenolepis diminuta and H. nana: Cross immunity against the lumen phase in BALB/c mice. Experimental Parasitology 64, 48–52.CrossRefGoogle Scholar
Mahato, S.B., Pal, B.C. & Nandy, A.K. (1992) Structure elucidation of two acylated triterpenoid bis-glycosides from Acacia auriculiformis Cunn. Tetrahedron 48, 6717–6728.CrossRefGoogle Scholar