Hostname: page-component-78c5997874-s2hrs Total loading time: 0 Render date: 2024-11-08T01:20:16.706Z Has data issue: false hasContentIssue false
  • English
  • Français

Effect of selenium and Ascaridia galli infection on antioxidant biomarkers in broiler chickens: a mathematical model for parasite reduction and host growth

Published online by Cambridge University Press:  01 December 2007

M. Gabrashanska ,
M. Galvez-Morros ,
S.E. Teodorova ,
S. Ermidou-Pollet  and
S. Pollet
M. Gabrashanska
Affiliation:
Institute for Experimental Pathology and Parasitology, Bulgarian Academy of Sciences, Acad., G. Bonchev str., bl. 25, 1113 Sofia, Bulgaria
M. Galvez-Morros
Affiliation:
Departamento de Quimica Analitica, Facultad de Ciencias Quimicas, Universidad Complutense, Ciudad Universitaria, 28040 Madrid, Spain
S.E. Teodorova*
Affiliation:
Institute for Nuclear Research and Nuclear Energy, Bulgarian Academy of Sciences, 72, Tzarigradsko shaussee, 1784 Sofia, Bulgaria
S. Ermidou-Pollet
Affiliation:
University of Medicine, Medical School, 73, Mikras Asias Str., Athens, Greece
S. Pollet
Affiliation:
University of Medicine, Medical School, 73, Mikras Asias Str., Athens, Greece
*
*Fax: +3592 975 36 19 E-mail: seteodor@tea.bg
Get access Rights & Permissions [Opens in a new window]

Abstract

The activity of selenium-dependent glutathione peroxidase (GPX), liver concentration of vitamin E, and plasma and liver selenium levels were used for estimation of the antioxidant status of broiler chickens infected with Ascaridia galli. These biomarkers were recorded in an experiment covering 70 days p.i. At the same time the establishment rate of A. galli in chicken intestines, gain in the host body weight and chicken survival were studied. Broiler chickens (Cobb hybrids) were infected with 1450 embryonated A. galli eggs and treated with Sel-plex. A mathematical model was applied to determine the rate of nematode reduction and the relative rate of gain of host body weight, which are essential kinetic parameters of parasite–host interaction. The activity of GPX increased with both elevated selenium and reduced infection levels. The concentrations of selenium and vitamin E, and the GPX activity in the infected chickens demonstrated a similar pattern of change with time after day 30 p.i. The supplementation of the broilers with dietary selenium in the form of Sel-plex improved their antioxidant status. Increases by 29% in vitamin E concentration, 15% in GPX activity, and 22% in liver selenium concentration, respectively, were recorded in the infected and treated, compared to infected and untreated broilers.

Type
Research Papers
Information
Journal of Helminthology , Volume 81 , Issue 4 , December 2007 , pp. 399 - 408
Copyright
Copyright © Cambridge University Press 2007

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Avanzo, J.L., De Mendonça, Jr., Pugine, S.M.P. & Cesar, M.C. (2001) Effect of vitamin E and selenium on resistance to oxidative stress in chicken superficial pectorialis muscle. CBP Part C 129, 163–173.Google Scholar
Barrett, J. (1981) Biochemistry of parasitic helminths. 308 pp. London and Basingstoke, MacMillan Publishers Ltd.CrossRefGoogle Scholar
Besarabov, B. & Melnikova, I. (2001) Hypovitaminoses in farm fowl. Moscow, State Academy of Veterinary Medicine and Biotechnologies ‘K.I. Skriabin’ (in Russian).Google Scholar
Beutler, E. (1984) Red cell metabolism: a manual of biochemical methods. 3rd edn.New York, Crune and Stratton.Google Scholar
Bieri, J., Tollwer, T. & Catigan, A. (1979) Simultaneous determination of alfa-tocoferol and retinol in plasma or red blood cells by high pressure liquid chromatography. American Journal of Clinical Nutrition 30, 686–690.CrossRefGoogle Scholar
Boscolo, P., Di Gioaecchino, M., Qiao, A. & Sabbioni, E. (2004) Work, environment, immunity system and human health. International Journal of Immunopathology and Pharmacology 17 (Suppl. 2), 1–2.Google ScholarPubMed
Caygill, C.P.J., Lucy, J.A. & Diplock, A.T. (1971) The effect of vitamin E on the intracellular distribution of the different oxidation states of selenium in rat liver. Biochemical Journal 125, 407–416.CrossRefGoogle ScholarPubMed
Chandra, K. (1999) Nutrition and immunology from the chick to cellular biology and back again. Proceedings of the Nutrition Society 58(13), 681–683.CrossRefGoogle Scholar
Colnago, G., Jensen, L. & Long, P. (1984) Effect of selenium and vitamin E on the development of immunity to coccidiosis in chickens. Poultry Science 63, 1136–1143.CrossRefGoogle ScholarPubMed
Davtjan, E.A. (1982) On microelement-like factors changing host–parasite relationships during helminthiases and on the possibility for their application for raising of animal production. Biological Journal of Armenia 30 (4), 2–5(in Russian).Google Scholar
Derda, M., Wandurska-Nowak, E. & Hadas, E. (2004) Changes in the level of antioxidants in the blood from mice infected with Trichinella spiralis. Parasitology Research 93, 207–210.CrossRefGoogle ScholarPubMed
De Souza, A., De Olivera, G., Vanderpas, J., De Castro, S., Kivera, M. & Aranjo-Jorge, T. (2003) Selenium supplementation at low doses contributes to the decrease in heart damage in experimental Trypanosoma cruzi infection. Parasitology Research 91, 51–54.CrossRefGoogle Scholar
Dhur, A., Gaban, P. & Hereberg, S. (1990) Relationship between selenium, immunity and resistance against infection. Comparative Biochemistry and Physiology C 96, 271–280.CrossRefGoogle ScholarPubMed
Finch, J. & Turner, R. (1996) Effect of selenium and vitamin E on the immune responses of domestic animals. Research in Veterinary Science 60, 97–106.CrossRefGoogle ScholarPubMed
Fridovich, I. (1978) Superoxide radicals, superoxide dismutase and the aerobic lifestyle. Photochemistry and Photobiology 28, 733–734.CrossRefGoogle ScholarPubMed
Gabrashanska, M., Teodorova, S.E. & Mitov, M. (2002) The effect of cobalt compounds on uninfected and Ascaridia galli-infected chickens: a kinetic model for Ascaridia galli populations and chicken growth. Journal of Helminthology 76, 303–310.CrossRefGoogle ScholarPubMed
Gabrashanska, M., Teodorova, S.E., Galvez-Morros, M. & Mitov, M. (2004a) Effects of glycine–metal compounds on Ascaridia galli-infected chickens expressed by a kinetic model. Journal of Helminthology 78, 25–32.CrossRefGoogle ScholarPubMed
Gabrashanska, M., Teodorova, S.E., Galvez-Morros, M., Tsocheva-Gaytandzhieva, N. & Mitov, M. (2004b) Administration of Zn–Co–Mn basic salt to chickens with ascaridiosis. I. A mathematical model for Ascaridia galli population and host growth with and without treatment. Parasitology Research 93, 235–241.CrossRefGoogle Scholar
Gomez, K., Solana, M. & Levander, O. (2002) Host selenium deficiency increases the severity of chronic inflammatory myopathy in Trypanosoma cruzi-inoculated mice. Journal of Parasitology 88, 541–547.CrossRefGoogle ScholarPubMed
Hung, K. & Yang, S. (2002) Inhibitory effect of Se on Cryptosporidium parvum infection in vitro and in vivo. Biological Trace Element Research 90, 261–272.CrossRefGoogle Scholar
Kehrer, J. (1993) Free radicals as mediators of tissue injury and disease. Critical Reviews in Toxicology 23, 21–48.CrossRefGoogle ScholarPubMed
Khaled, N.F., Mahmoud, A.R. & El-Banna, R. (2004) Influence of dietary selenium source supplementation on broiler performance, certain blood chemistry, thyroid metabolism and carcass characteristics 22. Arbeitstagung Mengen- und Spurenelemente. Jena, Friedrich Schiller Universität.Google Scholar
Kolodziejczyk, L., Siemieniuk, E. & Skrzydlewska, E. (2005) Antioxidant potential of rat liver in experimental infection with Fasciola hepatica. Parasitology Research 96, 367–372.CrossRefGoogle ScholarPubMed
Leeson, S. & Summers, J.D. (1991) Commercial poultry nutrition. Guelph, Ontario, University Books.Google Scholar
Levander, O., Ager, A. & Beck, M. (1995) Vitamin E and selenium: contrasting and interacting determinants of host resistance to parasitic and viral infections. Proceeding of the Nutrition Society 54, 435–487.Google ScholarPubMed
Morel, F., Doussiere, P. & Vagnis, P. (1991) The superoxide-generating oxidase of phagocytic cells. Physiological, molecular and pathological aspects. European Journal of Biochemistry 201, 523–546.CrossRefGoogle ScholarPubMed
Paul, J. & Barrett, J. (1980) Peroxide metabolism in the cestode Hymenolepis diminuta and Moniezia expansa. Journal of Parasitology 10, 121–124.Google Scholar
Payne, R. & Southern, L. (2005) Comparison of inorganic and organic selenium sources for broilers. Poultry Science 84, 898–902.CrossRefGoogle ScholarPubMed
Permin, A., Pearman, M., Wansen, P., Bisgaard, M.F. & Frandsen, F. (1997) On investigation in different media for embryonation of Ascaridia galli eggs. Helminthologia 34, 75–79.Google Scholar
Rivera, K., De Souza, A., Aranjo-Jorge, T., De Castaro, S. & Vanderpas, J. (2003) Trace elements, innate immune response and parasites. Clinical Chemistry and Laboratory Medicine 41, 1020–1025.CrossRefGoogle ScholarPubMed
Rotruck, J., Pope, A., Ganther, H., Swanson, A., Hateman, D. & Hoekstra, W. (1973) Selenium biochemical role as a component of glutathione peroxidase. Science 179, 58–90.CrossRefGoogle ScholarPubMed
Sanchez-Campos, S., Tunon, M.J., Gonzalez, P. & Gonzalez-Gallego, J. (1999) Oxidative stress and changes in liver antioxidant enzymes induced by experimental dicroceliosis in hamsters. Parasitology Research 85, 468–474.CrossRefGoogle ScholarPubMed
Scott, M., Lnesheim, M.C. & Young, R.J. (1982) Nutrition of the chicken. 3rd edn.Ithaca, New York, M.L. Scott, Associates.Google Scholar
Teodorova, S.E. & Gabrashanska, M. (2002) Optimal treatment of Ascaridia galli-infected chickens with salts of trace elements and a kinetic model for chicken growth. Journal of Helminthology 76, 79–85.CrossRefGoogle Scholar
United States National Research Council, (1994) Nutrient requirements of poultry. 9th edn.155 pp. Washington DC, National Academy Press.Google Scholar
Vassilev, I., Ossikowski, E., Bozhkov, S., Kamburov, P., Bankov, I. & Rupova, L. (1973) On the pathogenesis of ascaridiosis in fowl. Bulletin of the Central Helminthological Laboratory, Sofia 16, 43–58.Google Scholar
Watkinson, J. (1966) Fluorometric determination of selenium in biological material with 2,3-diaminonaphthalene. Analytical Chemistry 38, 92–97.CrossRefGoogle ScholarPubMed
Yaroshenko, F.O., Dvorska, J.E., Suraj, P.F. & Sparks, N.H.C. (2003) Selenium-enriched eggs as a source of selenium for human consumption. Applied Biotechnology, Food Science and Policy 1, 13–23.Google Scholar