Hostname: page-component-78c5997874-s2hrs Total loading time: 0 Render date: 2024-11-20T04:24:02.171Z Has data issue: false hasContentIssue false
  • English
  • Français

Efficacy of eprinomectin pour-on treatment in sheep naturally infected with Dictyocaulus filaria and Cystocaulus ocreatus

Published online by Cambridge University Press:  07 January 2011

F. Kırcalı Sevimli ,
E. Kozan  and
N. Doğan
F. Kırcalı Sevimli*
Affiliation:
Department of Parasitology, Faculty of Veterinary Medicine, Afyon Kocatepe University, Afyonkarahisar, Turkey
E. Kozan
Affiliation:
Department of Parasitology, Faculty of Veterinary Medicine, Afyon Kocatepe University, Afyonkarahisar, Turkey
N. Doğan
Affiliation:
Department of Biostatistics, Faculty of Medicine, Afyon Kocatepe University, Afyonkarahisar, Turkey
*
*Fax: +90 272 2281349 E-mail: feridekircali@hotmail.com
Get access Rights & Permissions [Opens in a new window]

Abstract

The efficacy of eprinomectin on Dictyocaulus filaria and Cystocaulus ocreatus in naturally infected sheep was evaluated in the present study. In total, 30 infected sheep were randomly divided into two groups: treated (n = 15) and untreated (n = 15). A single pour-on dose of eprinomectin (0.5 mg/kg) was administered to the treated group. No medication was used in the untreated group. Faecal larval counts were performed on pre-treatment (day 0) and post-treatment (days 7, 14, 21 and 42) days. Eprinomectin was found to be 100% effective against D. filaria on day 7 post-treatment when compared with the untreated group and it maintained this effect on days 14, 21 and 42. However, the decrease in faecal larval count of C. ocreatus was found to be 86, 86 and 91%, on days 14, 21 and 42, respectively.

Type
Research Papers
Information
Journal of Helminthology , Volume 85 , Issue 4 , December 2011 , pp. 472 - 475
Copyright
Copyright © Cambridge University Press 2011

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Aguirre, D.H., Gaido, A.B., Cafrune, M.M., Castelli, M.E., Mangold, A.J. & Guglielmone, A.A. (2005) Eprinomectin pour-on for control of Boophilus microplus (Canestrini) ticks (Acari: Ixodidae) on cattle. Veterinary Parasitology 127, 157–163.CrossRefGoogle ScholarPubMed
Akçapınar, H. (1994) Türkiye koyun ırkları. pp. 108–123in Akçapınar, H. (Ed.) Koyun yetiştiriciliği 1. Ankara, Baskı, Medisan yayınları.Google Scholar
Alvinerie, M., Lacoste, E., Sutra, J.F. & Chartier, C. (1999a) Some pharmacokinetics parameters of eprinomectin in goats following pour-on administration. Veterinary Research Communications 23, 449–455.CrossRefGoogle ScholarPubMed
Alvinerie, M., Sutra, J.F., Galtier, P. & Mage, C. (1999b) Pharmacokinetics of eprinomectin in plasma and milk following topical administration to lactating dairy cattle. Research in Veterinary Science 67, 229–232.CrossRefGoogle ScholarPubMed
Bliss, E.L. & Greiner, E.C. (1985) Efficacy of fenbendazole and cambendazole against Muellerius capillaris in dairy goats. American Journal of Veterinary Research 46, 1923–1925.Google ScholarPubMed
Bürger, H.J. (1992) Protostrongylidosen von Schaf und Ziege. pp. 307–314in Eckert, J., Kutzer, E., Rommel, M., Bürger, H.J. & Körting, W. (Eds) Veterinärmedinische Parasitologie. Berlin, Verlag P. Parey.Google Scholar
Cabaret, J. (1991) Efficacy of netobimin against Muellerius capillaris and resistant strain of digestive tract strongyles in dairy goats. American Journal of Veterinary Research 52, 1313–1315.CrossRefGoogle ScholarPubMed
Chartier, C., Etter, E., Pors, I. & Alvinerie, M. (1999) Activity of eprinomectin in goats against experimental infections with Haemonchus contortus, Teladorsagia circumcincta and Trichostrongylus colubriformis. Veterinary Record 23, 99–100.CrossRefGoogle Scholar
Cramer, L.G., Pitt, S.R., Rehbein, S., Gogolewski, R.P., Kunkle, B.N., Langholff, W.K., Bond, K.G. & Maciel, A.E. (2000) Persistent efficacy of topical eprinomectin against nematode parasites in cattle. Parasitology Research 86, 944–946.CrossRefGoogle ScholarPubMed
Cremers, H.J. (1983) Effectiveness of oxfendazole against Muellerius capillaris (Nematoda: Protostrongylidae) in goats. Tijdschrift voor Diergeneeskunde 108, 863–867.Google ScholarPubMed
Cringoli, G., Rinaldi, L., Veneziano, V. & Capelli, G. (2003) Efficacy of eprinomectin pour-on against gastrointestinal nematode infections in sheep. Veterinary Parasitology 102, 203–209.CrossRefGoogle Scholar
Cringoli, G., Rinaldi, L., Veneziano, V., Capelli, G. & Rubino, R. (2004) Effectiveness of eprinomectin pour-on against gastrointestinal nematodes of naturally infected goats. Small Ruminant Research 55, 209–213.CrossRefGoogle Scholar
Dupuy, J., Chartier, C., Sutra, J.F. & Alvinerie, M. (2001) Eprinomectin in dairy goats: dose influence on plasma levels and excretion in milk. Parasitology Research 87, 294–298.CrossRefGoogle Scholar
Geurden, T. & Vercruysse, J. (2007) Field efficacy of eprinomectin against a natural Muellerius capillaris infection in dairy goats. Veterinary Parasitology 147, 190–193.CrossRefGoogle ScholarPubMed
Gıcık, Y., Arslan, M.Ö., Sarı, B. & Umur, Ş. (2002) Doğal Enfekte Gebe Koyunlarda Mide-Bağırsak ve Akciğer Nematodlarına Doramectin'in Etkisi. Turkish Journal of Veterinary and Animal Sciences 26, 793–797.Google Scholar
Gogolewski, R.P., Allerton, G.R., Pitt, S.R., Thompson, D.R., Langholff, W.K., Hair, J.A., Folton, R.K. & Eagleson, J.S. (1997) Effect of simulated rain, coat length and exposure to natural climatic conditions on the efficacy of a topical formulation of eprinomectin against endoparasites of cattle. Veterinary parasitology 69, 95–102.CrossRefGoogle ScholarPubMed
Habela, M., Moreno, A., Gragera-Slikker, A., Gomez, J.M., Montes, G., Rodriguez, P. & Alvinerie, M. (2006) Efficacy of eprinomectin pour-on in naturally Oestrus ovis infested merino sheep in Extremadura, South-West Spain. Parasitology Research 99, 275–280.CrossRefGoogle ScholarPubMed
Hele, O. (1986) The efficacy of fenbendazole and albendazole against the lungworm Muellerius capillaris in goats. Veterinary Parasitology 22, 293–301.CrossRefGoogle Scholar
Hendrix, C.M. (1998) Diagnostic veterinary parasitology. 2nd edn. 262 pp. St. Louis, USA, Mosby Inc.Google Scholar
Hidalgo-Argüello, M.R., Díez-Baños, N. & Rojo-Vázquez, F.A. (2002) Efficacy of moxidectin 1% injectable and 0.2% oral drench against natural infection by Dictyocaulus filaria in sheep. Veterinary Parasitology 107, 95–101.CrossRefGoogle ScholarPubMed
Hodošček, L., Grabnar, I., Milčinski, L., Süssinger, A., Eržen, N.K., Zadnik, T., Pogačnik, M. & Cerkvenik-Flajs, V. (2008) Linearity of eprinomectin pharmacokinetics in lactating dairy sheep following pour-on administration: Excretion in milk and exposure of suckling lambs. Veterinary Parasitology 154, 129–136.CrossRefGoogle ScholarPubMed
Höglund, J., Ganheim, C. & Alenius, S. (2003) The effect of treatment with eprinomectin on lungworms at early patency on the development of immunity in young cattle. Veterinary Parasitology 114, 205–214.CrossRefGoogle ScholarPubMed
Jones, L.C. & Worley, D.E. (1997) Use of fenbendazole for long-term control of protostrongylid lungworms in free-ranging Rocky Mountain bighorn sheep. Journal of Wildlife Diseases 33, 365–367.CrossRefGoogle ScholarPubMed
Kassai, T. (1999) Veterinary helminthology. 1st edn. 88 pp. Oxford, UK, Butterworth-Heinemann.Google Scholar
Kulo, A., Chartier, C. & Cabaret, J. (1994) Variability in susceptibility to anthelmintics of the lungworm Muellerius capillaris first-stage larvae. Relationship to dairy-goat farms and previous exposure to febantel treatment. Veterinary Research 25, 537–543.Google ScholarPubMed
Malone, F.E. (2007) Parasitic bronchitis and pneumonia. pp. 236–238in Aitken, I.D. (Ed.) Diseases of sheep. 4th edn. Oxford, Blackwell Science.CrossRefGoogle Scholar
Panitz, E., Godfrey, R.W. & Dodson, R.E. (2002) Resistance to ivermectin and the effect of topical eprinomectin on faecal egg counts in St Croix white hair sheep. Veterinary Research Communications 26, 443–446.CrossRefGoogle Scholar
Papadopoulos, E., Sotiraki, S., Himonas, C. & Fthenakis, G.C. (2004) Treatment of small lungworm infestation in sheep by using moxidectin. Veterinary Parasitology 121, 329–336.CrossRefGoogle Scholar
Pitt, S.R., Langholff, W.K., Eagleson, J.S. & Rehbein, S. (1997) The efficacy of eprinomectin against induced infections of immature (fourth larval stage) and adult nematode parasites in cattle. Veterinary Parasitology 73, 119–128.CrossRefGoogle Scholar
Rehbein, S. & Visser, M. (2002) Efficacy of ivermectin delivered via a controlled-release capsule against small lungworms (Protostrongylidae) in sheep. Journal of Veterinary Medicine Series B 49, 313–316.CrossRefGoogle Scholar
Rehbein, S., Winter, R., Visser, M., Maciel, A.E. & Marley, S.E. (2005) Chorioptic mange in dairy cattle: treatment with eprinomectin pour-on. Parasitology Research 98, 21–25.CrossRefGoogle ScholarPubMed
Schnieder, T. (2000) Helminthosen der Wiederkäuer. pp. 192–295in Rommel, M., Eckert, O., Kutzer, E., Körting, W. & Schnieder, T. (Eds) Veterinärmedizinische Parasitologie 5. Berlin, Parey Buchverlag.Google Scholar
Shoop, W.L., Egerton, J.R., Eary, C.H., Haines, H.W., Michael, B.F., Mrozik, H., Eskola, P., Fisher, M.H., Slayton, L., Ostlind, D.A., Skelly, B.J., Fulton, R.K., Barth, D., Costa, S., Gregory, L.M., Campbell, W.C., Seward, R.L. & Turner, M.J. (1996) Eprinomectin: a novel avermectin for use as a topical endectocide for cattle. International Journal for Parasitology 26, 1237–1242.CrossRefGoogle ScholarPubMed
Soulsby, E.J.L. (1982) Helminths, arthropods and protozoa of domesticated animals. 7th edn. 149–155 pp. London, Bailliere Tindal.Google Scholar
Van Wyk, J.A., Cabaret, J. & Michael, L.M. (2004) Morphological identification of nematode larvae of small ruminants and cattle simplified. Veterinary Parasitology 119, 277–306.CrossRefGoogle ScholarPubMed
Williams, J.C., Stuedemann, J.A., Bairden, K., Kerbouf, D., Ciordia, H., Hubert, J., Broussard, S.D., Plue, R.E., Alva-Valdez, R., Baggott, D.G., Pinkall, N. & Eagleson, J.S. (1997) Efficacy of a pour-on formulation of eprinomectin (MK-397) against nematode parasites of cattle, with emphasis on inhibited early fourth-stage larvae of Ostertagia spp. American Journal of Veterinary Research 58, 379–383.CrossRefGoogle ScholarPubMed
Wood, I.B., Amaral, N.K., Bairde, K., Duncan, J.L., Kassai, T., Malone, J.B., Pankavich, J.A., Reinecke, R.K., Slocombe, O., Taylor, S.M. & Vercruysse, J. (1995) World Association for the Advancement of Veterinary Parasitology (W.A.A.V.P.) second edition of guidelines for evaluating the efficacy of anthelmintics in ruminants (bovine, ovine, caprine). Veterinary parasitology 58, 181–183.CrossRefGoogle ScholarPubMed