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Cross protection against Taenia taeniaeformis in rats vaccinated with non-viable oncospheres of Asian Taenia or T. saginata

Published online by Cambridge University Press:  05 June 2009

A. Ito ,
P.C. Fan ,
W.C. Chung  and
M. Suzuki
A. Ito
Affiliation:
Department of Parasitology, Gifu University School of Medicine, Gifu 500, Japan
P.C. Fan
Affiliation:
Department of Parasitology, National Yang-Ming Medical College, Taipei, Taiwan, Republic of China
W.C. Chung
Affiliation:
Department of Parasitology, Taipei Medical College, Taipei, Taiwan, Republic of China
M. Suzuki
Affiliation:
Department of Parasitology, Gumma University School of Medicine, Maebashi, Japan
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Abstract

It was determined to examine whether rats injected with non-viable oncospheres of Asian Taenia or Taenia saginata became resistant to challenge infection with eggs of Taenia taeniaeformis, since (a) metacestodes of Asian Taenia and T. taeniaeformis develop in the liver of pigs and rats, respectively, and (b) Asian Taenia and T. saginata have human origins. Rats injected intravenously or subcutaneously with complete Freund's adjuvant with non-viable oncospheres of Asian Taenia showed statistically significant resistance to challenge infection with eggs of T. taeniaeformis, whereas those injected with non-viable oncospheres of T. saginata did not show any resistance.

Type
Research Note
Information
Journal of Helminthology , Volume 68 , Issue 1 , March 1994 , pp. 83 - 85
Copyright
Copyright © Cambridge University Press 1994

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