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Increased susceptibility of Atlantic salmon Salmo salar to infections with Gyrodactylus derjavini induced by dexamethasone bath treatment

Published online by Cambridge University Press:  12 April 2024

C.V. Nielsen  and
K. Buchmann
C.V. Nielsen*
Affiliation:
Department of Veterinary Microbiology, Section of Fish Diseases, Royal Veterinary and Agricultural University, Stigbøjlen 4, DK-1870, Frederiksberg C, Denmark
K. Buchmann
Affiliation:
Department of Veterinary Microbiology, Section of Fish Diseases, Royal Veterinary and Agricultural University, Stigbøjlen 4, DK-1870, Frederiksberg C, Denmark
*
*Author for correspondence Fax: +45 35 28 27 11 Email: cvn@kvl.dk
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Abstract

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Dexamethasone, a known immunosuppressant, was administered by bath or injection to Atlantic salmon Salmo salar (Conon stock) to study if this treatment could affect the susceptibility of fish to infections with a Danish strain of Gyrodactylus derjavini (Monogenea). Three groups of S. salar (Conon stock) were immersion treated either with 10, 60 or 240 μg dexamethasone l-1 water, respectively. In addition, one group (positive control) was treated intraperitoneally with 200 μg dexamethasone per fish and one negative control group was kept untreated. A single G. derjavini parasite was placed on the anal fin of each fish and the infection was subsequently monitored weekly for 6 weeks. An increase in parasite populations on the salmon was positively correlated with the amount of immunosuppressant used. Infection levels in the group immersion treated with dexamethasone (240 μg l-1 water) and in the i.p. treated positive control group were significantly higher compared to the untreated control group.

Type
Review Article
Information
Journal of Helminthology , Volume 77 , Issue 1 , March 2003 , pp. 65 - 68
Copyright
Copyright © Cambridge University Press 2003

References

Anderson, D.P., Robertson, B.S. & Dixon, O.W. (1982) Immunosuppression induced by a corticosteroid or an alkylating agent in rainbow trout (Salmo gairdneri) administered a Yersinia ruckeri bacterin. Developmental and Comparative Immunology 2, 197–204.Google Scholar
Baker, I.J., Solar, I.I. & Donaldson, E.M. (1988) Masculinization of chinook salmon (Oncorhynchus tshawtscha) by immersion treatments using 17 α-methyltestosterone around the time of hatching. Aquaculture 72, 359–367.CrossRefGoogle Scholar
Bakke, T.A. & MacKenzie, K. (1993) Comparative susceptibility of native Scottish and Norwegian stocks of Atlantic salmon: laboratory experiments. Fisheries Research 17, 69–85.CrossRefGoogle Scholar
Bakke, T.A., Soleng, A. & Harris, P.D. (1999) The susceptibility of Atlantic salmon (Salmo salar L.) × brown trout (Salmo trutta L.) hybrids to Gyrodactylus salaris Malmberg and Gyrodactylus derjavini Mikailov. Parasitology 119, 467–481.CrossRefGoogle ScholarPubMed
Buchmann, K. (1997) Population increase of Gyrodactylus derjavini on rainbow trout induced by testosterone treatment of the host. Diseases of Aquatic Organisms 30, 145–150.CrossRefGoogle Scholar
Buchmann, K. & Uldal, A. (1997) Gyrodactylus derjavini infections in four salmonids: comparative host susceptibility and site selection of parasites. Diseases of Aquatic Organisms 28, 201–209.CrossRefGoogle Scholar
Cable, J., Harris, P.D. & Bakke, T.A. (2000) Population growth of Gyrodactylus salaris (Monogenea) on Norwegian and Baltic Atlantic salmon (Salmo salar) stocks. Parasitology 121, 621–629.CrossRefGoogle ScholarPubMed
Harris, P.D., Soleng, A. & Bakke, T.A. (2000) Increased susceptibility of salmonids to the monogenean Gyrodactylus salaris following administration of hydrocortisone acetate. Parasitology 120, 57–64.CrossRefGoogle Scholar
Houghton, G. & Matthews, R.A. (1990) Immunosuppression in the juvenile carp, Cyprinus carpio L.: The effect of the corticosteroids treamcinolone acetonide and hydrocortisone 21 hemisuccinate (cortisol) on acquired immunity and the humoral antibody response to Ichthyophthirius multifiliis Fouquet. Journal of Fish Diseases 13, 269–280.CrossRefGoogle Scholar
Larsen, A.H., Bresciani, J. & Buchmann, K. (2002) Interactions between ecto- and endoparasites in trout Salmo trutta . Veterinary Parasitology 103, 167–173.CrossRefGoogle ScholarPubMed
Lindenstrøm, T. & Buchmann, K. (1998) Dexamethasone treatment increases susceptibility of rainbow trout, Oncorhynchus mykiss (Walbaum), to infections with Gyrodactylus derjavini Mikailov. Journal of Fish Diseases 21, 29–38.CrossRefGoogle ScholarPubMed
Lindenstrøm, T & Buchmann, K. (2000) Acquired resistance in rainbow trout against Gyrodactylus derjavini . Journal of Helminthology 74, 155–160.CrossRefGoogle ScholarPubMed
Margolis, L., Esch, G.W., Holmes, J.C., Kuris, A.M. & Schad, G.A. (1982) The use of ecological terms in parasitology (report of an ad hoc committee of the American Society of Parasitologists). Journal of Parasitology 68, 131–133.CrossRefGoogle Scholar
Pickering, A.D. & Duston, J. (1983) Administration of cortisol to brown trout, Salmo trutta L., and its effects on the susceptibility to Saprolegnia infection and furunculosis. Journal of Fish Biology 23, 163–175.CrossRefGoogle Scholar