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An unusual cutaneous presentation of Hodgkin's disease

Published online by Cambridge University Press:  29 June 2007

A. De Grip*
Affiliation:
Department of ENT Surgery, Kent County Ophthalmic and Aural Hospital, Maidstone, Kent
J. B. Schofield
Affiliation:
Cellular Pathology Department and Marilyne Welsh Research Unit, Preston Hall Hospital, Aylesford, Kent, UK.
J. C. Shotton
Affiliation:
Department of ENT Surgery, Kent County Ophthalmic and Aural Hospital, Maidstone, Kent
*
Address for correspondence: A. de Grip, Flat 14, Orchard Residences, Kent and Canterbury Hospital, Canterbury, Kent CT1 3NG.

Abstract

Hodgkin's disease is a neoplasm of lymphoid tissue defined histopathologically by the presence of Reed-Sternberg cells in an appropriate cellular background. Hodgkin's disease extends only rarely into the skin. Sinus and fistula formation has been reported in very occasional cases. We now report a case of a 34-year-old woman presenting with a cutaneous lesion surrounding a discharging blind-ending sinus in the neck, subsequently diagnosed as Hodgkin's disease. To our knowledge this form of presentation of Hodgkin's disease has not been reported in the English literature before, and at the same time we would like to outline the difficulties in diagnosis encountered with these cutaneous lymphoid lesions.

Type
Clinical Records
Copyright
Copyright © JLO (1984) Limited 1999

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References

Alba, D., Lobato, S. D., Alvarez-Sala, R., Villasante, C., Echevarria, C. (1994) Tracheooesophageal fistula as the presenting manifestation of Hodgkin's lymphoma. Post-graduate Medicine Journal 70: 4950.CrossRefGoogle ScholarPubMed
Benninghoff, D. L., Medina, A., Alexander, L. L., Camiel, M. R. (1970) The mode of spread of Hodgkin's disease to the skin. Cancer 26: 11351140.3.0.CO;2-J>CrossRefGoogle ScholarPubMed
Derrick, E. K., Price, M. L., Deutsch, G. P. (1991) Cutaneous extension of Hodgkin's disease. Journal of the Royal Society of Medicine 84: 684685.CrossRefGoogle ScholarPubMed
Glaser, S. L., Jarrett, R. F. (1996) The epidemiology of Hodgkin's disease. Ballière's Clinical Haematology 9: 3.Google ScholarPubMed
Dowd, P. M., Munro, D. D., Stansfeld, A. G. (1981) Lymphomatoid papulosis and primary cutaneous Hodgkin's disease. Journal of the Royal Society of Medicine 74: 6871.CrossRefGoogle ScholarPubMed
Dunphy, C. H., Saravia, O., Varvares, M. A. (1996) Hodgkin's disease primarily involving Waldeyer's ring. Archives of Pathology and Laboratory Medicine 120: 285287.Google ScholarPubMed
Greven, K. M., Evans, L. S. (1992) The occurrence and management of esophageal fistulas resulting from Hodgkin's disease. Cancer 69: 10311033.3.0.CO;2-Q>CrossRefGoogle ScholarPubMed
Hayes, T. G., Rabin, V. R., Rosen, T., Zubler, M. A. (1990) Hodgkin's disease presenting in the skin: Case report and review of the literature. Journal of the American Academy of Dermatology 22: 944947.CrossRefGoogle ScholarPubMed
Kadin, M. E. (1991) Ki-1-Positive Anaplastic large-cell lymphoma: A clinicopathologic entity? Journal of Clinical Oncology 9(4): 533536.CrossRefGoogle ScholarPubMed
Kaplan, H. S. (1980) Hodgkin's Disease. Harvard University Press Cambridge, MA. p 52.Google ScholarPubMed
Ozdemirli, M., Mankin, H. J., Aisenberg, A. C., Harris, N. L. (1996) Hodgkin's disease presenting as a solitary bone tumour; A report of four cases and review of the literature. American Cancer Society 77(1): 7988.Google ScholarPubMed
Rubins, J. (1978) Cutaneous Hodgkin's disease: Indolent course and control with chemotherapy. Cancer 42: 12191221.3.0.CO;2-3>CrossRefGoogle ScholarPubMed
Sioutos, N., Kerl, H., Murphy, S. B., Kadin, M. E. (1994) Primary cutaneous Hodgkin's disease: Unique clinical, morphologic, and immunophenotypic findings. American Journal of Dermatopathology 16(1): 28.CrossRefGoogle ScholarPubMed
Smith, J. L., Butler, J. J. (1980) Skin involvement in Hodgkin's disease. Cancer 45: 354361.3.0.CO;2-#>CrossRefGoogle ScholarPubMed
Tassies, D., Sierra, J., Montserrat, E., Marti, R., Estrach, T., Rozman, C. (1992) Specific cutaneous involvement in Hodgkin's disease. Hematological Oncology 10: 7579.CrossRefGoogle ScholarPubMed
Wang, H. H., Lach, L., Kadin, M. E. (1992) Epidemiology of lymphomatoid papulosis. Cancer 70: 29512957.3.0.CO;2-7>CrossRefGoogle ScholarPubMed
White, R. M., Patterson, J. W. (1985) Cutaneous involvement in Hodgkin's disease. Cancer 55: 11361145.3.0.CO;2-T>CrossRefGoogle ScholarPubMed
Williams, M. V. (1980) Spontaneous regression of cutaneous Hodgkin's disease. British Medical Journal 1: 903.CrossRefGoogle Scholar
Yuen, A. R., Horning, S. J. (1996) Recent advances in Hodgkin's disease. Current Opinions in Hematology 3: 273278.CrossRefGoogle ScholarPubMed