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Changes in the pattern of rhinoscleroma in Egypt: updated experience

Published online by Cambridge University Press:  19 September 2019

A M Gamea ,
F A Y El Tatawi  and
M A Gamea
A M Gamea*
Affiliation:
Department of Otolaryngology, Tanta University, Egypt
F A Y El Tatawi
Affiliation:
Department of Pathology, Tanta University, Egypt
M A Gamea
Affiliation:
Department of Otolaryngology, Misr University for Science and Technology, Giza, Egypt
*
Author for correspondence: Prof Ahmed M Gamea, Department of Otolaryngology, Tanta University, Al-Geish St., Tanta 31512, Egypt E-mail: ahmgama@yahoo.com
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Abstract

Objective

This study aimed to record recent changes in the incidence and clinical and histopathological patterns of rhinoscleroma in the middle of Nile Delta in Egypt.

Method

Twenty-eight patients with rhinoscleroma were included in this study. Patients who were attending the Department of Otolaryngology at Tanta University Hospitals from January 2014 to January 2019 were included. Cases were diagnosed by clinical, bacteriological and histopathological data. Nasal biopsies were taken for histopathological and electron microscopy studies. All patients received a twelve-week course of 500 mg ciprofloxacin tablets twice daily.

Results

The rate of rhinoscleroma was shown to be decreasing compared with previous studies. In this study, the disease mainly affected the nose without involvement of the palate, lips, Eustachian tube or bronchi. Histopathological and electron microscopy analyses showed that most cases were in the atrophic and fibrotic stages rather than the granulomatous stage of disease.

Conclusion

The incidence of rhinoscleroma in Egypt is decreasing and its clinical and histopathological patterns are changing to less advanced forms. This may be explained by the improvement in socioeconomic conditions and methods of treatment.

Keywords

RhinoscleromaCiprofloxacinIncidenceEgyptGranulomaNose DiseasesMicroscopy, Electron
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 133 , Issue 10 , October 2019 , pp. 879 - 883
Copyright
Copyright © JLO (1984) Limited, 2019 

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Footnotes

Prof A M Gamea takes responsibility for the integrity of the content of the paper

References

1Gonzalez-Angulo, A, Marques-Monter, H, Greenberg, SD, Cerbon, J. Ultrastructure of nasal scleroma. Ann Otol Rhinol Laryngol 1965;74:1022–7Google Scholar
2Hoffman, EO, Loose, LD, Harkin, JC. The Mikulicz cell in rhinoscleroma. Am J Pathol 1973;73:47–58Google Scholar
3Gadomski, CF. Rhinoscleroma. Arch Otolaryng 1939;29:681–94Google Scholar
4Hara, HJ. Scleroma. Laryngoscope 1957;67:695–708Google Scholar
5Fisher, ER, Dimling, C. Rhinoscleroma. Arch Pathol 1964;78:501–12Google Scholar
6Gamea, AM, El-Tatawi, FAY. Ethmoidal scleroma: endoscopic diagnosis and treatment. J Laryngol Otol 1992;106:807–9Google Scholar
7Hara, HJ, Pratt, OB, Levine, MG, Hoyt, RE. Scleroma: a clinico-pathological study of seven cases in one family. Ann Otol Rhinol Laryngol 1947;56:769–83Google Scholar
8Botros, G, Hamilton, PK, Floyd, TM, Mufti, A, Imam, A. Scleroma in Egypt. Ann Otol Rhinol Laryngol 1954;63:1031–55Google Scholar
9Gamea, AM, El-Tatawi, FAY. The effect of rifampicin on rhinoscleroma: an electron microscopic study. J Laryngol Otol 1990;104:772–7Google Scholar
10Gamea, AM. Local rifampicin in treatment of rhinoscleroma. J Laryngol Otol 1988;102:319–21Google Scholar
11Eltatawi, F. Effect of ciprofloxacin on rhinoscleroma: an EM study. Otolaryngol-Head and Neck Surg 2010;143:273Google Scholar
12Gaafar, HA, Gaafar, AH, Nour, YA. Rhinoscleroma: an updated experience through the last 10 years. Acta Otolaryngol 2011;131:440–6Google Scholar
13El-Mofty, A. Histological examination of scleroma. Ann Otol Rhinol Laryngol 1962;71:377–81Google Scholar
14Gamea, AM. Role of endoscopy in diagnosing scleroma in its uncommon sites. J Laryngol Otol 1990;104:619–21Google Scholar