Hostname: page-component-cd9895bd7-dzt6s Total loading time: 0 Render date: 2024-12-19T00:24:01.016Z Has data issue: false hasContentIssue false
  • English
  • Français

Incidence of neoplasia in patients with unilateral epiphora

Published online by Cambridge University Press:  15 July 2015

T Bewes ,
R Sacks ,
P L Sacks ,
D Chin ,
N Mrad ,
G Wilcsek ,
K Tumuluri  and
R Harvey
T Bewes*
Affiliation:
St Vincent's Clinical School, Faculty of Medicine, University of New South Wales, Sydney, Australia Rhinology and Skull Base Research Group, St Vincent's Centre for Applied Medical Research, University of New South Wales, Sydney, Australia
R Sacks
Affiliation:
Rhinology and Skull Base Research Group, St Vincent's Centre for Applied Medical Research, University of New South Wales, Sydney, Australia Australian School of Advanced Medicine, Macquarie University, Sydney, Australia
P L Sacks
Affiliation:
Rhinology and Skull Base Research Group, St Vincent's Centre for Applied Medical Research, University of New South Wales, Sydney, Australia
D Chin
Affiliation:
Rhinology and Skull Base Research Group, St Vincent's Centre for Applied Medical Research, University of New South Wales, Sydney, Australia
N Mrad
Affiliation:
Rhinology and Skull Base Research Group, St Vincent's Centre for Applied Medical Research, University of New South Wales, Sydney, Australia
G Wilcsek
Affiliation:
Rhinology and Skull Base Research Group, St Vincent's Centre for Applied Medical Research, University of New South Wales, Sydney, Australia
K Tumuluri
Affiliation:
Rhinology and Skull Base Research Group, St Vincent's Centre for Applied Medical Research, University of New South Wales, Sydney, Australia Australian School of Advanced Medicine, Macquarie University, Sydney, Australia
R Harvey
Affiliation:
St Vincent's Clinical School, Faculty of Medicine, University of New South Wales, Sydney, Australia Rhinology and Skull Base Research Group, St Vincent's Centre for Applied Medical Research, University of New South Wales, Sydney, Australia Australian School of Advanced Medicine, Macquarie University, Sydney, Australia
*
Address for correspondence: Dr Therese Bewes, St Vincent's Centre for Applied Medical Research, Level 4 Lowy Packer Building, 405 Liverpool Street, Darlinghurst, NSW 2010, Australia Fax: (+61) 2 8382 4901 E-mail: tessbewes@gmail.com
Get access Rights & Permissions [Opens in a new window]

Abstract

Background:

Nasolacrimal duct obstruction is common and is usually a result of benign stricture formation. Although neoplasia near or around the lacrimal system may produce epiphora, the incidence of neoplasia from within the lacrimal system as a cause of nasolacrimal duct obstruction is not well documented.

Methods:

A retrospective study was performed on all patients undergoing dacryocystorhinostomy with a history of epiphora. The incidence of patients with operative findings of intra-lacrimal neoplasm was sought. Histopathologically confirmed cases were included.

Results:

The study comprised 537 patients, who underwent a total of 631 endoscopic dacryocystorhinostomy procedures between January 1998 and July 2013. Non-stenotic causes of nasolacrimal duct obstruction were encountered in 3.01 per cent of dacryocystorhinostomy procedures, and included neoplastic, inflammatory and infectious pathologies. Inverted papilloma was the most common cause, encountered in 0.79 per cent of dacryocystorhinostomy operations.

Conclusion:

These findings suggest that neoplasia is an uncommon but not a rare cause of nasolacrimal duct obstruction. Surgical teams performing high numbers of dacryocystorhinostomy procedures should be aware of such pathology and patients counselled appropriately.

Keywords

DacryocystorhinostomyLacrimal Apparatus DiseasesNeoplasmsIncidencePapilloma, Inverted
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 129 , Supplement S3 , July 2015 , pp. S53 - S57
Copyright
Copyright © JLO (1984) Limited 2015 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Footnotes

Presented as a poster at the Australian Society of Otolaryngology Head and Neck Surgery 2014 Annual Scientific Meeting, 29 March – 1 April 2014, Brisbane, Australia.

References

1Nemet, AY, Vinker, S. Associated morbidity of nasolacrimal duct obstruction–a large community based case–control study. Graefes Arch Clin Exp Ophthalmol 2014;252:125–30CrossRefGoogle ScholarPubMed
2Woog, JJ. The incidence of symptomatic acquired lacrimal outflow obstruction among residents of Olmsted County, Minnesota, 1976–2000 (an American Ophthalmological Society thesis). Trans Am Ophthalmol Soc 2007;105:649–66Google ScholarPubMed
3Shigeta, K, Takegoshi, H, Kikuchi, S. Sex and age differences in the bony nasolacrimal canal: an anatomical study. Arch Ophthalmol 2007;125:1677–81CrossRefGoogle ScholarPubMed
4Groessl, SA, Sires, BS, Lemke, BN. An anatomical basis for primary acquired nasolacrimal duct obstruction. Arch Ophthalmol 1997;115:71–4CrossRefGoogle ScholarPubMed
5Zolli, CL, Shannon, GM. Dacryocystorhinostomy: a review of 119 cases. Ophthalmic Surg 1982;13:905–10Google ScholarPubMed
6Anderson, NG, Wojno, TH, Grossniklaus, HE. Clinicopathologic findings from lacrimal sac biopsy specimens obtained during dacryocystorhinostomy. Ophthal Plast Reconstr Surg 2003;19:173–6CrossRefGoogle ScholarPubMed
7Amin, RM, Hussein, FA, Idriss, HF, Hanafy, NF, Abdallah, DM. Pathological, immunohistochemical and microbiological analysis of lacrimal sac biopsies in patients with chronic dacrocystitis. Int J Ophthalmol 2013;6:817–26Google ScholarPubMed
8Merkonidis, C, Brewis, C, Yung, M, Nussbaumer, M. Is routine biopsy of the lacrimal sac wall indicated at dacryocystorhinostomy? A prospective study and literature review. Br J Ophthalmol 2005;89:1589–91CrossRefGoogle ScholarPubMed
9Linberg, JV, McCormick, SA. Primary acquired nasolacrimal duct obstruction. A clinicopathologic report and biopsy technique. Ophthalmology 1986;93:1055–63CrossRefGoogle ScholarPubMed
10Mauriello, JA Jr, Palydowycz, S, DeLuca, J. Clinicopathologic study of lacrimal sac and nasal mucosa in 44 patients with complete acquired nasolacrimal duct obstruction. Ophthal Plast Reconstr Surg 1992;8:13–21CrossRefGoogle ScholarPubMed
11Tucker, N, Chow, D, Stockl, F, Codère, F, Burnier, M. Clinically suspected primary acquired nasolacrimal duct obstruction: clinicopathologic review of 150 patients. Ophthalmology 1997;104:1882–6CrossRefGoogle ScholarPubMed
12Lee-Wing, MW, Ashenhurst, ME. Clinicopathologic analysis of 166 patients with primary acquired nasolacrimal duct obstruction. Ophthalmology 2001;108:2038–40CrossRefGoogle ScholarPubMed
13Bernardini, FP, Moin, M, Kersten, RC, Reeves, D, Kulwin, DR. Routine histopathologic evaluation of the lacrimal sac during dacryocystorhinostomy: how useful is it? Ophthalmology 2002;109:1214–17CrossRefGoogle Scholar
14Knežević, M, Stojković, M, Jovanović, M, Stanković, Z, Rašić, DM. A 7-year prospective study of routine histopathological evaluation of the lacrimal sac wall incisional biopsy specimens obtained during external dacryocystorhinostomy in adults and a review of the literature. Med Oncol 2012;29:396–400CrossRefGoogle Scholar
15Sandison, A. Common head and neck cases in our consultation referrals: diagnostic dilemmas in inverted papilloma. Head Neck Pathol 2009;3:260–2CrossRefGoogle ScholarPubMed