Hostname: page-component-cd9895bd7-gbm5v Total loading time: 0 Render date: 2024-12-22T21:15:18.904Z Has data issue: false hasContentIssue false
  • English
  • Français

Inverted papilloma with osteogenesis in the anterior ethmoid and frontal sinuses

Published online by Cambridge University Press:  16 July 2009

K Tsuzuki ,
T Nishigami ,
H Takebayashi ,
A Sakaguchi ,
H Oka ,
K Fukazawa  and
M Sakagami
K Tsuzuki*
Affiliation:
Department of Otolaryngology, Hyogo College of Medicine, Japan
T Nishigami
Affiliation:
Department of Pathology, Hyogo College of Medicine, Japan
H Takebayashi
Affiliation:
Department of Otolaryngology, Hyogo College of Medicine, Japan
A Sakaguchi
Affiliation:
Department of Otolaryngology, Hyogo College of Medicine, Japan
H Oka
Affiliation:
Department of Otolaryngology, Hyogo College of Medicine, Japan
K Fukazawa
Affiliation:
Fukazawa Ear, Nose and Throat Clinic, Kobe, Japan
M Sakagami
Affiliation:
Department of Otolaryngology, Hyogo College of Medicine, Japan
*
Address for correspondence: Dr Kenzo Tsuzuki, Department of Otolaryngology, Hyogo College of Medicine, 1-1 Mukogawa, Nishinomiya, Hyogo, 663-8501, Japan. Fax: +81 798 41 8976 E-mail: kenzo@hyo-med.ac.jp
Get access Rights & Permissions [Opens in a new window]

Abstract

Objective:

We report a rare case of new bone formation (osteogenesis) within an inverted papilloma, occurring in the ethmoid and frontal sinuses.

Method:

The histopathological and radiological findings, differential diagnosis, and treatment of tumour-induced osteogenesis are discussed.

Results:

A 68-year-old man complained of headache and left-sided, purulent rhinorrhoea of five years' duration. On nasal endoscopy, lesions similar to inflammatory nasal polyps were seen. Pre-operative radiological images demonstrated opacification of the left nasal cavity and anterior ethmoid and frontal sinuses, plus a bone-density lesion. The mass with bony lesion was completely removed endoscopically. The mass was histopathologically diagnosed as an inverted papilloma surrounding bony tissue. Furthermore, the histopathological findings (including immature bony tissue rimmed by osteoblasts) indicated an extremely rare case of inverted papilloma induced osteogenesis. Six months after surgery, no recurrence was detected.

Conclusion:

This case highlights the importance of clinical awareness of tumour-induced osteogenesis.

Keywords

Nasal CavityParanasal SinusesInverted PapillomaOsteogenesis
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 124 , Issue 2 , February 2010 , pp. 230 - 233
Copyright
Copyright © JLO (1984) Limited 2009

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1Ward, N. A mirror of the practice of medicine and surgery in the hospitals of London. London Hospital Lancet 1854;ii:480–2CrossRefGoogle Scholar
2Billroth, T. Tissue of the Mucosa of Polyps [in German]. Berlin: Reimer, 1855Google Scholar
3Lawson, W, Ho, BT, Shaari, AM, Biller, HF. Inverted papilloma: a report of 112 cases. Laryngoscope 1995;105:282–8CrossRefGoogle ScholarPubMed
4Unlu, HH, Songu, M, Ovali, GY, Nese, N. Inverted papilloma with new bone formation: report of three cases. Am J Rhinol 2007;21:607–10CrossRefGoogle ScholarPubMed
5Dadas, B, Ercan, I, Başak, T. Inverted papilloma with new bone formation in ethmoidofrontal region. Otolaryngol Head Neck Surg 2006;134:343–4CrossRefGoogle ScholarPubMed
6Krouşe, JH. Development of a staging system for inverted papilloma. Laryngoscope 2000;110:965–8CrossRefGoogle ScholarPubMed
7Krouşe, JH. Endoscopic treatment of inverted papilloma; safety and efficacy. Am J Otolaryngol 2001;22:87–99CrossRefGoogle ScholarPubMed
8Wormald, PJ, Ooi, E, van Hasselt, CA, Nair, S. Endoscopic removal of sinonasal inverted papilloma including endoscopic medial maxillectomy. Laryngoscope 2003;113:867–73CrossRefGoogle ScholarPubMed
9Eller, R, Sillers, M. Common fibro-osseous lesions of the paranasal sinuses. Otolaryngol Clin North Am 2006;39:585–600CrossRefGoogle ScholarPubMed
10Jacono, AA, Sclafani, AP, Van de Walter, T, McCormick, S, Frenz, D. Metaplastic bone formation in nasal polyps with histologic presence of transforming growth factor β-1 (TGFβ-1) and bone morphogenetic proteins (BMPs). Otolaryngol Head Neck Surg 2001;125:96–7CrossRefGoogle ScholarPubMed