Hostname: page-component-78c5997874-8bhkd Total loading time: 0 Render date: 2024-11-18T23:23:20.277Z Has data issue: false hasContentIssue false
  • English
  • Français

Malignant vagal paraganglioma

Published online by Cambridge University Press:  29 June 2007

R. M. Walsh ,
E. J. Leen ,
M. J. Gleeson  and
O. H. Shaheen
R. M. Walsh*
Affiliation:
Department of Otolaryngology and Head and Neck Surgery, Guys Hospital, St Thomas Street, London, UK
E. J. Leen
Affiliation:
Department of Otolaryngology and Histopathology, Guys Hospital, St Thomas Street, London, UK
M. J. Gleeson
Affiliation:
Department of Otolaryngology and Head and Neck Surgery, Guys Hospital, St Thomas Street, London, UK
O. H. Shaheen
Affiliation:
Department of Otolaryngology and Head and Neck Surgery, Guys Hospital, St Thomas Street, London, UK
*
Address for correspondence: Mr R. M. Walsh, F.R.C.S.(ORL), Department of Communication and Neuroscience, Keele University, Keele, Staffordshire sT5 5BG.
Get access Rights & Permissions [Opens in a new window]

Abstract

Vagal paraganglioma is a rare usually benign tumour of neural crest origin. The malignant form of this tumour i s very uncommon and the diagnosis is made on the basis of its clinical behaviour rather than its histological appearance. We report a case of vagal paraganglioma metastatic to adjacent cervical nodes and discuss the diagnosis and management of this tumour.

Keywords

ParagangliomaGlomus tumourVagus nerveNeoplasm metastasis
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 111 , Issue 1 , January 1997 , pp. 83 - 88
Copyright
Copyright © JLO (1984) Limited 1997

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Arts, H. A., Fagan, P. A. (1991) Vagal body tumours. Otolaryngology - Head and Neck Surgery 105: 78–85.CrossRefGoogle Scholar
Barnes, L., Taylor, S. R. (1991) Vagal paragangliomas: a clinical, pathological and DNA assessment. Clinical Otolaryngology 16: 376–382.CrossRefGoogle ScholarPubMed
Batsakis, J. G. (1974) Tumours of the Head and Neck. 1st Edition, Williams and Wilkins Co., Baltimore, MD, pp 280–288.Google Scholar
Birrell, J. H. W. (1953) The vagal body and its tumor. Australian and New Zealand Journal of Surgery 23: 48–54.CrossRefGoogle Scholar
Browne, J. D., Fisch, U., Valavanis, A. (1993) Surgical therapy of glomus vagale tumors. Skull Base Surgery 3; 182–192.CrossRefGoogle ScholarPubMed
Bogdasarian, R. S., Lotz, P. R. (1979) Multiple simultaneous paragangliomas of the head and neck in association with multiple retroperitoneal phaeochromocytomas. Otolaryngology - Head and Neck Surgery 87: 64–65.CrossRefGoogle Scholar
Burman, S. O. (1955) The vagal body tumor. Annals of Surgery 141: 488–489.CrossRefGoogle ScholarPubMed
Chaudry, A. P., Haar, J. G., Koul, A., Nickerson, P. A. (1979) A non-functioning paraganglioma of vagus nerve. An ultrastructural study.Cancer 43; 1689–1701.3.0.CO;2-5>CrossRefGoogle Scholar
Chen, E., DeSanto, L., Gaffey, T. (1985) Intravagal paragangliomas. Ear, Nose and Throat Journal 64: 190–195.Google Scholar
Cornford, E. J., Wastie, M. L., Morgan, D. A. (1992) Malignant paraganglioma of the mediastinum: a further diagnostic aid and therapeutic use of radiolabelled MIBG. British Journal of Radiology 65: 75–77.CrossRefGoogle Scholar
Davidson, J., Gullane, P. (1988) Glomus vagale tumours. Otolaryngology - Head and Neck Surgery 99: 66–70.CrossRefGoogle Scholar
Druck, N. S., Spector, G. J., Ciralsky, R. H., Ogura, R. H. (1976) Malignant glomus vagale. Report of a case and review of the literature. Archives of Otolaryngology 102: 634–636.CrossRefGoogle ScholarPubMed
Endicott, J. N., Maniglia, A. J. (1980) Glomus vagale. Laryngoscope 90: 1604–1611.CrossRefGoogle ScholarPubMed
Gee, M. S., Kliewer, K. E., Hinton, D. R. (1992) Nucleolar organizer regions in paragangliomas of the head and neck. Archives of Otolaryngology, Head and Neck Surgery 118: 380–383.CrossRefGoogle ScholarPubMed
Glenner, G. G., Grimley, P. M. (1974) Tumours of the extraadrenal paraganglion system (including chemoreceptors). Atlas of Tumor Pathology. 2nd series, Washington, Armed Forces Institute of Pathology, pp 1–90.Google Scholar
Heinrich, M. C., Harris, A. E., Bell, W. R. (1985) Metastatic intravagal paraganglioma. Case report and review of the literature. American Journal of Medicine 78: 1017–1024.CrossRefGoogle ScholarPubMed
Hesselink, J., Davis, K., Taveras, J. (1981) Selective arteriography of glomus typanicum and jugulare tumours. American Journal of Neuroradiology 2: 289–297.Google Scholar
Jackson, C. G., Glasscock, M. E., Harris, P. F. (1982) Glomus tumors - diagnosis, classification and management of large lesions. Archives of Otolaryngology 108: 401–406.CrossRefGoogle ScholarPubMed
Jackson, C. G. (1993) Neurotologic skull base surgery for glomus tumors, section III. Diagnosis for treatment planning and treatment options. Laryngoscope 103(11) (suppl. 60): 17–22.CrossRefGoogle Scholar
Johnstone, P. A. S., Foss, R. D., Desilets, D. J. (1990) Malignant jugulotympanic paragangliomas. Archives of Pathology and Laboratory Medicine 114: 976–979.Google Scholar
Kahn, L. B. (1976) Vagal body tumor (non-chromaffin paraganglioma, chemodectoma and carotid body-like tumor) with cervical node metastasis and familial association. Ultrastructural study and review. Cancer 38: 2367–2377.3.0.CO;2-3>CrossRefGoogle Scholar
Karusseit, V. O., Lodder, J. V. (1987) Functioning vagal body tumour. British Journal of Surgery 74: 1184.CrossRefGoogle ScholarPubMed
Kissel, P., Floquet, J., Andre, J. M., Picard, L., Frisch, R. (1976) Les chemodectomes due vague: hypotheses pathogeniques a partir d'une revue du cent cas. Revue Neurologique (Paris) 132: 391–404.Google Scholar
Kliewer, K. E., Cochran, A. J. (1989) A review of the histology, ultrastructure, immunohistology and molecular biology of extra-adrenal paragangliomas. Archives of Pathology and Laboratory Medicine 113; 1209–1218.Google ScholarPubMed
Konefal, J. B., Pilepich, M. V., Spector, G. J., Perez, C. A. (1987) Radiaton therapy in the treatment of chemodectomas. Laryngoscope 97: 1331–1335.CrossRefGoogle Scholar
Lack, E. E., Cubilla, A. L., Woodruff, J. M., Fair, H. W. (1977) Paragangliomas of the head and neck region. A clinical study of 69 patients. Cancer 39: 397–409.3.0.CO;2-C>CrossRefGoogle ScholarPubMed
Lack, E. E., Cubilla, A. L., Woodruff, J. M. (1979) Paragangliomas of the head and neck region. A pathological study of tumours from 71 patients. Human Pathology 10: 191–218.CrossRefGoogle ScholarPubMed
Lattes, R., Waltner, J. G. (1949) Non-chromaffin paraganglioma of the middle ear. Cancer 2: 447.3.0.CO;2-E>CrossRefGoogle Scholar
Lattes, R. (1950) Non-chromaffin paragangliomas of the ganglion nodosum, carotid body and aortic arch-bodies. Cancer 3: 667–694.3.0.CO;2-I>CrossRefGoogle Scholar
Lawson, W. (1980) The neuroendocrine nature of the glomus cells: an experimental, ultrastructural and histochemical tissue culture study. Laryngoscope 90: 120–144.CrossRefGoogle ScholarPubMed
Levit, S. A., Sheps, S. G., Espinosa, R. E., Remine, W. H., Harrison, E. G. (1969) Catecholamine-secreting paraganglioma of the glomus-jugulare region resembling phaeochromocytoma. New England Journal of Medicine 281: 805–811.CrossRefGoogle Scholar
Linn, H., Proctor, B. (1956) Tumour of the ganglion nodosum of the vagus nerve. Laryngoscope 66: 1577–1581.CrossRefGoogle ScholarPubMed
Linnoila, R. I., Keiser, H. R., Steinberg, S. M., Lack, E. E. (1990) Histopathology of benign versus malignant sympathoadrenal paragangliomas: clinico-pathologic study of 120 cases including unusual histologic features. Human Pathology 21: 1168–1180.CrossRefGoogle Scholar
Mulligan, R. M. (1950) Chemodectoma in the dog. American Journal of Pathology 26: 680–681.Google Scholar
Nilssen, E., Wormald, P. J. (1996) The role of MIBG scintigraphy in the management of a case of metastatic glomus jugulare tumour. Journal of Laryngology and Otology 110: 373–375.CrossRefGoogle ScholarPubMed
Ogura, J. H., Spector, G. H., Gado, M. (1978) Glomus jugulare and vagale. Annals of Otolaryngology 87: 622–629.Google ScholarPubMed
Parkin, J. (1981) Familial multiple glomus tumours and phaeochromocytomas. Annals of Otolaryngology 90: 60–63.Google Scholar
Someren, A., Karcioglu, Z. (1977) Metastatic intravagal paraganglioma. Report of a case and review of the literature. American Journal of Clinical Practice 68; 400–408.Google Scholar
Som, P. M., Biller, H. F., Lawson, W., Sacher, M., Lanzieri, C. F. (1984) Parapharyngeal space masses: an updated protocol based upon 104 cases. Radiology 153: 149–156.CrossRefGoogle ScholarPubMed
Som, P. M., Braun, I. F., Shapiro, M. D., Reede, D. L., Curtin, H. D., Zimmerman, R. A. (1987) Tumors of the parapharyngeal space and upper neck: MR imaging characteristics. Radiology 164: 823–829.CrossRefGoogle ScholarPubMed
Spector, G. J., Compagno, J., Perez, C. A., Maisel, R. H., Ogura, J. H. (1975) Glomus jugulare tumors: effects of radiotherapy. Cancer 35: 1316–1321.3.0.CO;2-#>CrossRefGoogle ScholarPubMed
Stout, A. P. (1935) The malignant tumors of the peripheral nerves. American Journal of Cancer 25: 1–36.Google Scholar
Sundaram, M., Cope, M. (1976) Paragangliomas in the neck. British Journal of Surgery 63: 182–185.CrossRefGoogle ScholarPubMed
Tannir, N. M., Cortas, N., Allan, C. (1985) A functioning catecholamine-secreting vagal body tumor. Cancer 52: 932–935.3.0.CO;2-Y>CrossRefGoogle Scholar
Trail, M. L., Chambers, R. G. (1970) Chemodectomas of the vagal body. Laryngoscope 80: 568–577.Google ScholarPubMed
Urquhart, A. C., Johnson, J. T., Myers, E. N., Schechter, G. L. (1994) Glomus vagale: paraganglioma of the vagus nerve. Laryngoscope 104: 440–445.CrossRefGoogle ScholarPubMed
Van Barrs, F., VandenBroek, P., Cremers, C., Veldman, J. (1981) Familial nonchromafflnic paragangliomas. Laryngoscope 1: 988–996.Google Scholar
Van der Mey, A. G., Frijns, J. H., Cornelisse, C. J., Brons, E. N., Van Dulken, H., Terpstra, H. L., Schmidt, P. H. (1992) Does intervention improve the natural course of glomus tumors? A series of 108 patients seen in a 32-year-old period. Annals of Otology, Rhinology and Laryngology 101: 635–642.Google Scholar
White, E. G. (1935) Die struktur des glomus caroticum. Seine pathologies und physiologie und seine beziehung zum nerven system. Beitrage Zur Pathologie Und Anatomie 96: 177–227.Google Scholar
Wong, G. T. H., Stokes, B. A. R., Khangure, K. H., Apsimon, H. T., Sterrett, G. F. (1987) Glomus intravagale tumour: aspects of management. Australian and New Zealand Journal of Surgery 57: 199–204.CrossRefGoogle ScholarPubMed