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Serum enzymes in head and neck cancer. IV: 5-nucleotidase

Published online by Cambridge University Press:  29 June 2007

H. Lal*
Affiliation:
Department of Biochemistry, Medical College, Rohtak (India)
L. Kumar
Affiliation:
Department of E.N.T., Medical College, Rohtak (India)
G. S. Kohli
Affiliation:
Department of E.N.T., Medical College, Rohtak (India)
A. Sharma
Affiliation:
Department of Biochemistry, Medical College, Rohtak (India)
H. Goel
Affiliation:
Department of E.N.T., Medical College, Rohtak (India)
*
Dr. Harbans Lal, Department of Biochemistry, 12/9J Medical College, Rohtak-124001, India

Abstract

Serum 5-nucleotidase levels have been estimated in a group of 50 patients with head and neck cancer. The mean value was significantly higher in patients compared to the controls. In patients with non-malignant growths, the activity was comparable with the controls. The increase was higher in patients with proliferative lesions than those with ulcerative growths. Enzyme activity was found to be increased with the advancement in the stage of cancer. The rise was comparatively higher in patients with cervical metastasis. After radiotherapy, a gradual and significant reduction of serum 5-nucleotidase activity was observed.

Type
Main Articles
Copyright
Copyright © JLO (1984) Limited 1989

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