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Ultrastructure of nasal mast cells in normal subjects and patients with perennial allergic rhinitis

Published online by Cambridge University Press:  29 June 2007

A. B. Drake-Lee  and
Jaqueline Price
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Abstract

The ultrastructure of mast cells from the nine normal inferior turbinates were compared with those found in eight patients with perennial allergic rhinitis due to house dust mite allergy. Forty-six mast cells from normal patients were found in forty blocks and eighty cells were found in thirty-three blocks in patients with perennial allergy suggesting an increase of mast cell numbers in perennial allergy. There were no basophils outside the blood vessels and whole mast cells were found only in the submucosa. There was no difference in the morphology of cells of different sizes. Mast cells were more degranulated in the allergic mucosa. Degranulation, irrespective of cell size was found at all depths of the mucosa. A review of the literature covered the in vivo and in vitro descriptions of the ultrastructural morphology of human mast cells in the respiratory tract.

Keywords

RhinitsallergicMast cellElectron microscopy
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 105 , Issue 12 , December 1991 , pp. 1006 - 1013
Copyright
Copyright © JLO (1984) Limited 1991

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