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DNA Patents and Human Dignity

Published online by Cambridge University Press:  01 January 2021

Extract

Those objecting to human DNA patenting frequently do so on the grounds that the practice violates or threatens human dignity. For example, from 1993 to 1994, more than thirty organizations representing indigenous peoples approved formal declarations objecting to the National Institutes of Health's (NIH) bid to patent viral DNA taken from subjects in Papua New Guinea and the Solomon Islands. Although these were not patents on human DNA, the organizations argued that the patents could harm and exploit indigenous peoples and violate their cultural values. NIH eventually dropped one of its patent applications.

On May 18, 1995, 180 religious leaders, led by biotechnology critic Jeremy Rifkin, held a press conference objecting to DNA patenting in Washington, D.C. In their “Joint Appeal against Human and Animal Patenting,” these leaders decried any attempt to patent nature. Some of the more outspoken members of the Joint Appeal likened DNA patenting to slavery, while others objected to treating human beings as marketable commodities. In his recent book, The Biotech Century, Rifkin rehashed the objections to DNA patenting voiced by members of the Joint Appeal.

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Article
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Copyright © American Society of Law, Medicine and Ethics 2001

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References

In this essay, I will use the phrase “human DNA patenting” instead of the more popular phrase “human gene patenting” because the more popular idiom is misleading. The patents that have been approved by patent offices do not mention “human genes,” but usually describe “isolated and purified DNA sequences.” This is not a trivial point: A gene is a functional unit that carries the information needed to make a protein, which includes DNA that codes for the primary structure of the protein (the coding region) as well as DNA that regulates translation and transcription of the coding region. Moreover, some DNA sequences, such as genetic markers, are much smaller than genes. Some patents, such as patents on expressed sequence tags (ESTs), apply to genetic markers. See Wong, D., The ABCs of Gene Cloning (New York: Chapman and Hall, 1997). I would also like to point out that the notion of “human” DNA is a bit ambiguous since human beings share a large percentage of their DNA with chimpanzees, a slightly lesser percentage with pigs, and a still fair percentage with yeast. To make sense of this biological fact, by “human” DNA, I mean “DNA that is a part of a genome of a member of the species Homo sapiens.” Although much of the DNA in human DNA is structurally similar to DNA that occurs in non-human species, DNA is “human” by virtue of its functional role in a human genome. By way of comparison, the same automotive part, such as a fan belt, may be present in many different vehicles, but a fan belt is a Ford Ranger fan belt by virtue of its functional role (turning the fan) in a Ford Ranger truck. See Resnik, D., “The Morality of Human Gene Patents,” Kennedy Institute of Ethics Journal, 7, no. 1 (1997): 43–61.Google Scholar
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