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Cochrane's Linked Data Project: How it Can Advance our Understanding of Surrogate Endpoints

Published online by Cambridge University Press:  01 January 2021

Abstract

Cochrane has developed a linked data infrastructure to make the evidence and data from its rich repositories more discoverable to facilitate evidence-based health decision-making. These annotated resources can enhance the study and understanding of biomarkers and surrogate endpoints.

Type
Symposium Articles
Copyright
Copyright © American Society of Law, Medicine and Ethics 2019

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References

See <https://linkeddata.cochrane.org/> (last visited July 9, 2019).+(last+visited+July+9,+2019).>Google Scholar
Effective Practice and Organization of Care Group and Public Health, see <https://www.cochrane.org/about-us/our-global-community/review-group-networks> (last visited July 9, 2019).+(last+visited+July+9,+2019).>Google Scholar
Sampson, A. L., Singer, R. F., and Walters, G. D., “Uric Acid Lowering Therapies for Preventing or Delaying the Progression of Chronic Kidney Disease,” Cochrane Database of Systematic Reviews 10 (2017): Art. No.: CD009460, doi: http://dx.doi.org/10.1002/14651858.CD009460.pub2.Google Scholar
Graudal, N. A., Hubeck-Graudal, T., and Jurgens, G., “Effects of Low Sodium Diet Versus High Sodium Diet on Blood Pressure, Renin, Aldosterone, Catecholamines, Cholesterol, and Triglyceride,” Cochrane Database of Systematic Reviews 4 (2017): Art. No.: CD004022, doi: http://dx.doi.org/10.1002/14651858.CD004022.pub4.Google Scholar
Schuetz, P., Wirz, Y., Sager, R., et al., “Procalcitonin to Initiate or Discontinue Antibiotics in Acute Respiratory Rract Infections,” Cochrane Database of Systematic Reviews 10 (2017): Art. No.: CD007498, doi: http://dx.doi.org/10.1002/14651858.CD007498.pub3.Google Scholar
Marteau, T. M., French, D. P., Griffin, S. J. et al., “Effects of Communicating DNA-Based Disease Risk Estimates on Risk-Reducing Hehaviours,” Cochrane Database of Systematic Reviews 10 (2010): Art. No.: CD007275, doi: http://dx.doi.org/10.1002/14651858.CD007275.pub2.Google Scholar
Southern, K. W., Patel, S., Sinha, I. P., and Nevitt, S. J., “Correctors (Specific Therapies for Class II CFTR Mutations) for Cystic Fibrosis,” Cochrane Database of Systematic Reviews 8 (2018): Art. No.: CD010966, doi: http://dx.doi.org/10.1002/14651858.CD010966.pub2.Google Scholar
Schuit, E., Panagiotou, O. A., Munafò, M. R., et al., “Pharmaco-therapy for Smoking Cessation: Effects by Subgroup Defined by Genetically Informed Biomarkers,” Cochrane Database of Systematic Reviews 9 (2017): Art. No.: CD011823, doi: http://dx.doi.org/10.1002/14651858.CD011823.pub2.Google Scholar
Aabenhus, R., Jensen, J. U. S., Jørgensen, K. J. et al., “Biomarkers as Point-of-Care Tests to Guide Prescription of Antibiotics in Patients with Acute Respiratory Infections in Primary Care,” Cochrane Database of Systematic Reviews 11 (2014): Art. No.: CD010130, doi: http://dx.doi.org/10.1002/14651858.CD010130.pub2.Google Scholar
Petsky, H. L., Cates, C. J., Li, A., et al., “Tailored Interventions Based on Exhaled Nitric Oxide Versus Clinical Symptoms for Asthma in Children and Adults,” Cochrane Database of Systematic Reviews 4 (2009): Art. No.: CD006340, doi: http://dx.doi.org/10.1002/14651858.CD006340.pub3.Google Scholar
Alldred, S. K., Takwoingi, Y., Guo, B., et al., “First Trimester Ultrasound Tests Alone or in Combination with First Trimester Serum Tests for Down's Syndrome Screening,” Cochrane Database of Systematic Reviews 3 (2017): Art. No.: CD012600, doi: http://dx.doi.org/10.1002/14651858.CD012600; Rompianesi, G., Hann, A., Komolafe, O., et al., “Serum Amylase and Lipase and Urinary Trypsinogen and Amylase for Diagnosis of Acute Pancreatitis,” Cochrane Database of Systematic Reviews 4 (2017): Art. No.: CD012010, doi: http://dx.doi.org/10.1002/14651858.CD012010.pub2; Gupta, D., Hull, M. L., Fraser, I., et al., “Endometrial Biomarkers for the Non-Invasive Diagnosis of Endometriosis,” Cochrane Database of Systematic Reviews 4 (2016); Art. No.: CD012165. doi: http://dx.doi.org/10.1002/14651858.CD012165; Shaikh, N., Borrell, J. L., Evron, J., and Leeflang, M. M. G., “Procalcitonin, C-Reactive Protein, and Erythrocyte Sedimentation Rate for the Diagnosis of Acute Pyelonephritis in Children,” Cochrane Database of Systematic Reviews 1 (2015): Art. No.: CD009185. doi: http://dx.doi.org/10.1002/14651858.CD009185.pub2.Google Scholar
Hey, S. P. et al., “Challenges and Opportunities for Biomarker Validation,” Journal of Law, Medicine & Ethics 47, no. 3 (2019): 357-361; Shrager, J., Shapiro, M., and Hoos, W., “Is Cancer Solvable? Towards Efficient and Ethical Biomedical Science,” Journal of Law, Medicine & Ethics 47, no. 3 (2019): 369-373; S.P. Hey et al., Surrogate Endpoints and Drug Regulation: What Is Needed to Clarify the Evidence, Journal of Law, Medicine & Ethics 47, no. 3 (2019): 381-387; L.M. McShane, Biomarker Validation: Context and Complexities, Journal of Law, Medicine & Ethics 47, no. 3 (2019): 388-392; A.D. Zhang and J.S. Ross, Biomarkers as Surrogate Endpoints: Ongoing Opportunities for Validation, Journal of Law, Medicine & Ethics 47, no. 3 (2019): 393-395; A.D. Stern, Managing the Use and Dissemination of Information about Biomarkers: The Importance of Incentive Structures, Journal of Law, Medicine & Ethics 47, no. 3 (2019): 396-397.CrossRefGoogle Scholar